A kind of method for continuously preparing cyclopropylamine
A technology for cyclopropylamine and cyclopropylformamide, which is applied in the field of continuous preparation of cyclopropylamine, can solve the problems of difficult effective control of the reaction process, slow reaction rate, high equipment requirements, etc., and achieve high product yield, short reaction cycle, and low equipment investment Effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0029] as per figure 1 Shown process continuously prepares cyclopropylamine:
[0030] (1) Preparation of solution A: Add 75g of water to 22g of cyclopropanamide, and dissolve it in a water bath at 40°C under temperature control and stirring, then dilute to 100mL with water to prepare a solution with a density of cyclopropanamide solution close to 1 A;
[0031] (2) Prepare solution B: under temperature control and stirring in a water bath at 10-20°C, slowly add 23.5g of sodium hydroxide solid to 186g of sodium hypochlorite solution with an available chlorine content of 10.1%, add a small amount of water, dissolve it, and then add water Dilute to 160mL, prepare solution B;
[0032] (3) The solution A obtained in step (1) and the solution B obtained in step (2) are continuously passed into the micro-reaction equipment at a flow rate of 5mL / min and 8mL / min respectively, and the micro-reaction equipment mainly consists of a 40°C micro-sieve reactor and Composed of 90°C temperatu...
Embodiment 2
[0035] as per figure 1 Shown process continuously prepares cyclopropylamine:
[0036] (1) Preparation of solution A: add 70 g of water to 25 g of cyclopropanamide, dissolve in a water bath at 40°C with temperature control and stirring, and then dilute to 100 mL with water to prepare solution A;
[0037] (2) Prepare solution B: under temperature control and stirring in a water bath at 10-20°C, slowly add 25.9g of sodium hydroxide solid to 175g of sodium hypochlorite solution with an available chlorine content of 12.5%, and add a small amount of water to dissolve it, then water Dilute the volume to 200mL, and prepare solution B;
[0038] (3) The solution A obtained in step (1) and the solution B obtained in step (2) are continuously passed into the micro-reaction equipment at a flow rate of 5mL / min and 10mL / min respectively, and the micro-reaction equipment mainly consists of a 40°C membrane dispersion microreactor and Composed of 80°C temperature-controlled coils; the two sol...
Embodiment 3
[0041] as per figure 1 Shown process continuously prepares cyclopropylamine:
[0042] (1) Preparation of solution A: add 68 g of water to 30 g of cyclopropanamide, dissolve in a water bath at 50°C under temperature control and stirring, and then dilute to 100 mL with water to prepare solution A;
[0043] (2) Prepare solution B: under temperature control and stirring in a water bath at 20-30°C, slowly add 36.7g of sodium hydroxide solid to 216g of sodium hypochlorite solution with an available chlorine content of 12.5%, and add a small amount of water to dissolve it, and then add water Dilute to 250mL, prepare solution B;
[0044] (3) The solution A obtained in step (1) and the solution B obtained in step (2) are continuously passed into the micro-reaction equipment at a flow rate of 5mL / min and 12.5mL / min respectively, and the micro-reaction equipment is mainly composed of a 60°C membrane dispersion microreactor and 70°C temperature control coil; the two solutions are quickl...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More