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Composition used for tooth protection

A composition and tooth technology, applied in the field of tooth protection composition, can solve the problems of tooth surface contamination, insufficient acid etching, high personnel operation requirements, etc., to achieve the effect of protecting teeth and overcoming the loss of sealant

Active Publication Date: 2019-07-05
赵云峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The disadvantages of the existing pit and fissure sealant are high requirements for personnel operation, insufficient acid etching, and no chalky appearance after the tooth surface is dried. At the same time, water / oil is easily mixed in saliva or air gun compressed air during operation, Contamination of the etched tooth surface, causing the sealant to fall off

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0013] Example 1: Compositions for tooth protection

[0014] A composition for tooth protection, the fullerene C 60 and calcium fluoride are completely dissolved in ethyl acetate solvent according to the mass ratio of 60:1, and the fullerene C 60 and calcium fluoride in ethyl acetate. As other embodiments, the fullerene of the present invention can also use fullerene C 50 , fullerene C 70 , fullerene C 76 , fullerene C 78 , fullerene C 84 , fullerene C 90 and a combination of one or more of the embedded structure fullerenes. As another embodiment, the fullerene C 60 And calcium fluoride can be selected in (60-120):1 according to the mass ratio.

Embodiment 2

[0015] Embodiment 2: composition is used for the animal test of tooth protection

[0016] 1. Experimental method

[0017] Select 80 SPF-SD rats, half male and half female, all were weaned on the 18th day after birth, their body weight was recorded, and they were fed with Keyes cariogenic feed 2000# and 5% sucrose aqueous solution. During the 19-21d period, the mice were given antibacterial containing broad-spectrum antibiotics (2000g feed plus 2g ampicillin, 1000g 5% sucrose aqueous solution plus cephradine 1g), and no antibiotics were added to the feed at other times. Rat saliva was taken from rats aged 22 days with a sterile cotton swab and spread on a plate to detect the inhibition of endogenous Streptococcus mutans. Streptococcus mutans (1ml / rat) was inoculated in the oral cavity of rats at the age of 23-26 days for 4 consecutive days, and 10 rats were randomly selected at the age of 24-26 days for calibration. Under ether inhalation anesthesia, intraperitoneal injection ...

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Abstract

The present invention provides a composition used for tooth protection. The composition can be combined with a pit and fissure sealing technology to effectively prevent and treat caries. After the pitand fissure sealing technology is implemented, the tooth protection agent is coated on tooth surfaces to form a fullerene calcium fluoride protection layer. The composition can overcome a problem offalling off of a sealing agent on the one hand and can more effectively protect teeth for a long time on the other hand.

Description

technical field [0001] The invention relates to the technical field of tooth protection, in particular to a composition for tooth protection. Background technique [0002] Caries is a chronic and progressive disease in which cariogenic microorganisms and carbohydrates in dental plaque produce acids, which cause demineralization of dental hard tissues and disintegration of inorganic substances. According to the triple factor theory of caries occurrence, the prevention of caries is mainly to enhance the anti-caries ability of teeth, control plaque, especially inhibit the growth of cariogenic bacteria, and limit the intake of carbohydrates or find sugar substitutes. As far as anti-caries drugs are concerned, the main function is to enhance the anti-caries ability of teeth (such as fluoride, etc.) and control plaque to inhibit bacterial growth (such as chlorhexidine, etc.). [0003] At present, pit and fissure sealing is an effective method to prevent and treat dental caries. P...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/44A61P1/02A61P31/04A61K33/16
CPCA61K33/16A61K33/44A61P1/02A61P31/04A61K2300/00
Inventor 赵云峰
Owner 赵云峰
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