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A kind of cream for removing stretch marks and preparation method thereof

A technology for stretch marks and creams, which is applied to skin care preparations, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve the problem of poor activity of bioactive molecules, difficult absorption of macromolecules, and poor stability of plant extracts. and other problems to achieve the effect of improving elasticity and reducing the effect

Active Publication Date: 2022-08-05
广州雅纯化妆品制造有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to overcome the above problems and provide a cream for removing stretch marks and a preparation method thereof. In the prior art, the biologically active molecules have poor activity, the stability of plant extracts is not good, and macromolecules are not easily absorbed. Analysis of traditional microneedle types and their characteristics and factors affecting drug transdermal penetration through microneedles, and selecting a safer and better biodegradable sponge microneedle as the basis of the present invention

Method used

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  • A kind of cream for removing stretch marks and preparation method thereof
  • A kind of cream for removing stretch marks and preparation method thereof
  • A kind of cream for removing stretch marks and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 to 7 is an embodiment of a cream that removes stretch marks. The composition and weight percentage content of the embodiment 1 to 7 are shown in Table 2:

[0042] Table 2

[0043]

[0044]

[0045] Example 1 ~ 7 The preparation method of removing stretch marks, including the following steps:

[0046] (1) Removed ionic water, biophilic TM S. Total Cera stir up to 80 ± 2 ° C, stir and stir for 10 to 20 minutes to get a mixture A, and add the dispersed sodium hyaluronic acid, Huangyuan, glycerin, glycol, ilogenin, seaweed sugar to the above mixtures to the above mixtures. A mix in A to 80 ± 2 ℃, and the insulation continues to stir for 15-30 minutes to get a mixture B.

[0047] (2) Stir the mountain alcohol, horned sharkane, avocado fruit lipid oil, sunflower seed oil, nacilitic phenol, oatmeal oil, sweet tonsil oil, sucrose hard fatty lipate, nicheol ethyl, heating and heating to 80 ± 2 ° C, 5-15 minutes insulation; get a mixture C, then add a mixture C to a mix...

Embodiment 8

[0056] Safety tests for embodiments 1 ~ 7 and a cream prepared 1 to 11.

[0057] Test method: Chicken embryos, culvert cashmere membrane vascular test

[0058] Test results: Examples 1 ~ 7 and the proportion of 1 ~ 11 in CAMVA, the NC score is 1.5, the product is manifested as non -damage stimulation. At this time, the capillaries have no hemorrhage damage.

Embodiment 9

[0060] Example 1 ~ 7 and the effectiveness test of the proportion 1 ~ 11:

[0061] 1. Test method

[0062] test instrument:

[0063] Cutometer (Courage & Khazaka, Germany)

[0064] Skin texture tester VC98 (Courage & Khazaka, Germany)

[0065] Skin image analyzer Visia-CR (Canfield, the United States)

[0066] Libra, sensing 0.01g (Yingheng)

[0067] How to use samples: Apply it in an appropriate amount to the need, mollifies slightly, absorb absorption

[0068] Test person:

[0069] (1) Selected criteria:

[0070] ① Chinese women;

[0071] ② Age 22 to 50 years old (at the beginning of the test);

[0072] ③ Within 4 years after production;

[0073] ④ There are stretch marks;

[0074] ⑤ The subject should not be sensitive to commonly used cosmetics;

[0075] ⑥ The subject has not participated in other clinical studies in the past three months.

[0076] (2) The subject eliminates the standard

[0077] ① Use antihistamine or immunosuppressive agent for nearly a month;

[0078] ② Use an...

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Abstract

The invention discloses a cream for removing stretch marks and a preparation method thereof. The cream includes a skin conditioning agent, and the weight percentage of the skin conditioning agent in the cream is: 1-5% of hydroxyproline silanol , Complex ceramide Total Cera 0.1-0.5%, oligopeptide-1 0.1-1%, complex composed of asiaticoside and madecassoside 0.1-0.3%, palmitoyl pentapeptide-4, palmitoyl The complex composed of tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tripeptide-1, hexapeptide-9, composed of caffeine, siloxane triol alginate, 3-6% of the complex composed of butanediol, 1-5% of shea butter oil, 0.1-1% of the complex composed of red algae extracts and brown algae extracts, and 0.1-1% of sponge microneedles. The cream can significantly improve stretch mark elasticity, stretch mark uniformity, stretch mark roughness, reduce stretch marks and fade stretch marks.

Description

Technical field [0001] The invention involves the field of cosmetics technology, which is specifically involved a cream and preparation method that removes stretch marks. Background technique [0002] In recent years, with the release of the full second child policy, the peak of fertility has also arrived. For the mothers during pregnancy, a big trouble will also face stretch marks. According to reports, 60 % -90 % of pregnant women have stretch marks in the abdomen, chest, thighs, waist, and hips during pregnancy. [0003] Stretch marks are a type of expansion (also known as atrophy and white lines). During the pregnancy, pregnant women, the expression of hormone receptors and hormone levels in the body will change huge changes. Double skin, the receptor expression of therogens and glucocorticoids will also increase. Increased glucocorticoids can inhibit the activity and proliferation of fibroblasts, reduce the number of fibroblast synthetic elastic fibers and collagen, which hi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/9717A61K8/9711A61K8/92A61K8/73A61K8/68A61K8/64A61K8/63A61K8/55A61K8/49A61K8/41A61K8/36A61K8/34A61K8/02A61Q19/08
CPCA61K8/9789A61K8/9717A61K8/9711A61K8/922A61K8/733A61K8/73A61K8/68A61K8/64A61K8/63A61K8/553A61K8/4953A61K8/41A61K8/361A61K8/345A61K8/342A61K8/0295A61Q19/08A61K2800/5922A61K2800/592A61K2800/782
Inventor 刘山肖雄尹全尹向文浩
Owner 广州雅纯化妆品制造有限公司
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