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Vitamin E emulsion and preparation method thereof

A technology of vitamins and allantoin, applied in pharmaceutical formulas, cosmetic preparations, dressing preparations, etc., can solve problems such as difficult absorption of EGF, uncontrollable skin growth, and hyperplasia of nodules, so as to reduce pollution and relieve skin dryness , improve the effect of lipid metabolism

Active Publication Date: 2019-07-23
北京科学城日化有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the large molecular weight of human oligopeptide-1 (EGF), EGF is difficult to be absorbed under normal skin barrier conditions. If EGF is abused, it may lead to uncontrollable skin growth and the formation of "tumor"-like nodular hyperplasia. Oligopeptide-1 (EGF) cosmetics may have certain risks

Method used

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  • Vitamin E emulsion and preparation method thereof
  • Vitamin E emulsion and preparation method thereof

Examples

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preparation example 1

[0043] Preparation Example 1: ① Take fresh pig gallbladder, ligate its bile duct opening, rinse the surface, drain the water on the surface; then place the ligated pig gallbladder at -15°C and freeze for 6 hours to obtain frozen pork gallbladder;

[0044] ②Put the frozen pig gall at 20°C for 15 minutes; wipe the surface of the frozen pig gall with alcohol with a volume fraction of 75%, and then use a sterilized knife to cut a "ten" incision on the skin of the frozen pig gall , to ensure the integrity of the interior of the gallbladder and remove the gallbladder;

[0045] ③Place the gallbladder after removing the gall skin in a centrifuge tube and melt it at room temperature to obtain bile;

[0046] ④Centrifuge the bile at a speed of 4000r / min for 40min, remove the supernatant, take the precipitate, put the precipitate in a vacuum freeze dryer, lower the temperature to -20°C at a rate of 2°C / min, and keep it warm for 1h ; then cool down to -30°C at a speed of 0.3°C / min, and k...

preparation example 2

[0047] Preparation Example 2: ① Take fresh pig gallbladder, ligate its bile duct opening, rinse the surface, drain the water on the surface; then place the ligated pig gallbladder at -18°C for 7 hours to obtain frozen pork gallbladder;

[0048] ②Place the frozen pig gall at 23°C for 18 minutes; wipe the surface of the frozen pig gall with alcohol with a volume fraction of 75%, and then use a sterilized knife to cut a "ten" incision on the skin of the frozen pig gall , to ensure the integrity of the interior of the gallbladder and remove the gallbladder;

[0049] ③Place the gallbladder after removing the gall skin in a centrifuge tube and melt it at room temperature to obtain bile;

[0050] ④Centrifuge the bile at a speed of 5000r / min for 50min, remove the supernatant, take the precipitate, put the precipitate in a vacuum freeze dryer, cool the temperature to -22°C at a rate of 3°C / min, and keep warm for 1.3 h; then cool down to -33°C at a speed of 0.4°C / min, and keep warm fo...

preparation example 3

[0051] Preparation example 3: ① Take fresh pig gallbladder, ligate its bile duct opening, rinse the surface, and drain the water on the surface; then place the ligated pig gallbladder at -20°C for 8 hours to obtain frozen pork gallbladder;

[0052] ②Place the frozen pig gall at 25°C for 20 minutes; wipe the surface of the frozen pig gall with alcohol with a volume fraction of 75%, and then use a sterilized knife to cut a "ten" incision on the skin of the frozen pig gall , to ensure the integrity of the interior of the gallbladder and remove the gallbladder;

[0053] ③Place the gallbladder after removing the gall skin in a centrifuge tube and melt it at room temperature to obtain bile;

[0054] ④Centrifuge the bile at a speed of 6000r / min for 60min, remove the supernatant, take the precipitate, put the precipitate in a vacuum freeze dryer, lower the temperature to -25°C at a rate of 4°C / min, and keep warm for 1.5 h; then cool down to -35°C at a speed of 0.5°C / min, and keep wa...

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Abstract

The invention discloses a vitamin E emulsion and a preparation method thereof, and belongs to the technical field of cosmetics. The vitamin E emulsion comprises phase A, phase B and phase C. The phaseA comprises the following components in parts by weight: 60-70 parts of water, 15-20 parts of glycerol, 2-3 parts of Potassiam polyoxyethylene laurylether phosphate and 0.2-0.3 part of allantoin; thephase B comprises the following components in parts by weight: 10-12 parts of mineral oil, 2-3 parts of vitamin E and 2-3 parts of polydimethylsiloxane; and the phase C comprises the following components in parts by weight: 1-2 parts of glycoprotein freeze-dried powder. According to the invention, the cooperation of the glycoprotein freeze-dried powder, the vitamin E and the allantoin has a synergistic repair effect, and can effectively relieve the problem of dryness and pruritus of skin, and improve the lipid metabolism condition of the skin.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a vitamin E milk and a preparation method thereof. Background technique [0002] The main component of vitamin E milk is vitamin E (tocopherol), and the excipients are glycerin, ethanol, Pinga O, polysorbate 80, and Span 80, etc. It is suitable for dry skin and skin pruritus caused by seasonal changes; Vitamin E has excellent anti-oxidation, emollient, antipruritic and anti-acne scar effects. Therefore, vitamin E milk obtained by compounding traditional vitamin E with other raw materials can also be used in the field of cosmetics. [0003] In the prior art, the patent application document with the application number CN108904448A discloses a vitamin E milk spray and its preparation process. The weight ratio between its raw material components is: vitamin E 0.5-1.5, anhydrous Ethanol 5-15, glycerin 4-10, butanediol 0.5-5, polysorbate-80 0.3-1, sorbitan oleate 0.2-1, purified wat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/67A61K8/49A61Q19/00
CPCA61K8/4946A61K8/64A61K8/678A61Q19/00
Inventor 程贵昇
Owner 北京科学城日化有限公司
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