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Euryale ferox salisb extract for controlling postprandial blood sugar, and preparation method and application of euryale ferox salisb extract

A postprandial blood sugar and extract technology, applied in the field of extraction of natural plant active components, to achieve the effect of high active components, high activity, and simple extraction methods

Active Publication Date: 2019-08-06
JIANGXI AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is: aiming at the defects and deficiencies of the existing α-glucosidase inhibitors, to provide a Gorgon fruit extract, preparation method and application for postprandial blood sugar control

Method used

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  • Euryale ferox salisb extract for controlling postprandial blood sugar, and preparation method and application of euryale ferox salisb extract
  • Euryale ferox salisb extract for controlling postprandial blood sugar, and preparation method and application of euryale ferox salisb extract
  • Euryale ferox salisb extract for controlling postprandial blood sugar, and preparation method and application of euryale ferox salisb extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1: Preparation of Gorgon fruit extract

[0028] (1) Gorgon powder grinding: remove impurities such as stones and shells in the Gorgon raw material, use a pulverizer to pulverize, and sieve with a 60-mesh sieve to obtain Gorgon dry powder;

[0029] (2) Solvent extraction: according to the solid-liquid ratio (g / ml) of Gorgon dry powder / 60% acetone solution as 1 / 50, weigh 1000 g of Gorgon dry powder, add 50000 ml of 60% acetone solution, and place it in an ultrasonic-assisted extractor The extraction temperature is 55°C, and the extraction time is 50 minutes; after the extraction, centrifuge at 3000rmp / min for 10 minutes, and take the supernatant; repeat the extraction once for the precipitated part according to the above steps, and combine the two extractions;

[0030] (3) Concentration under reduced pressure: Carry out vacuum reduction and concentration treatment to the above-mentioned extract, remove the acetone therein, and obtain the aqueous solution of Gor...

Embodiment 2

[0033] Embodiment 2: Preparation of Gorgon fruit extract

[0034] (1) Gorgon powder grinding: remove impurities such as stones and shells in the Gorgon raw material, use a pulverizer to pulverize, and sieve with a 50-mesh sieve to obtain Gorgon dry powder;

[0035] (2) Solvent extraction: according to the solid-liquid ratio (g / ml) of Gorgon dry powder / 90% ethanol solution as 1 / 80, weigh 1000 g of Gorgon dry powder, add 80000 ml of 90% ethanol solution, and place it in an ultrasonic-assisted extractor The extraction temperature was 50°C, and the extraction time was 40 minutes; after the extraction, centrifuged at 2500rmp / min for 15 minutes, and the supernatant was taken; the precipitated part was extracted once again according to the above steps, and the two extractions were combined;

[0036] (3) Concentration under reduced pressure: Carry out vacuum reduction and concentration treatment to the above-mentioned extract, remove the ethanol therein, and obtain the aqueous solution ...

Embodiment 3

[0038] Embodiment 3: Preparation of Gorgon fruit extract

[0039] (1) Gorgon powder grinding: remove impurities such as stones and shells in the Gorgon raw material, use a pulverizer to pulverize, and sieve with a 60-mesh sieve to obtain Gorgon dry powder;

[0040] (2) Solvent extraction: according to the solid-liquid ratio (g / ml) of Gorgon fruit dry powder / ethyl acetate as 1 / 20, weigh 1000 grams of Gorgon fruit dry powder, add 20000 ml of ethyl acetate, and place it in an ultrasonic-assisted extractor For extraction, the extraction temperature is 60°C, and the extraction time is 60 minutes; after the extraction is completed, centrifuge at 3500rmp / min for 5 minutes, and take the supernatant; repeat the extraction once for the precipitated part according to the above steps, and combine the two extractions;

[0041] (3) Concentration under reduced pressure: Carry out vacuum reduction and concentration treatment to the above-mentioned extract, remove the ethyl acetate therein, an...

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Abstract

The invention relates to the technical field of extraction of a natural plant active component, and particularly discloses a euryale ferox salisb extract for controlling postprandial blood sugar, anda preparation method and application of the euryale ferox salisb extract. The euryale ferox salisb extract contains active components for restraining alpha-glucosidases. The preparation method comprises the steps of S1, grinding euryale ferox salisb to obtain euryale ferox salisb powder; S2, performing solvent extraction; S3, performing decompressed concentration; S4, performing freeze drying andthe like. The euryale ferox salisb extract contains phenol substances of gallic acid, digallic acid hexoside, (-)-epicatechin gallate ester, proanthocyanidins, catechin, gallic acid derivatives and the like, and the phenol substances are important ingredients for restraining digestion and absorption of starch, and have excellent restraining effects on the vitality of alpha-glucosidases and alpha-amylases. The euryale ferox salisb extract disclosed by the invention has the advantages that the raw materials are medicinal and edible, and extensive and easy to obtain, the extraction method is simple, the extraction condition is mild, the obtained euryale ferox salisb extract is high in active component, the euryale ferox salisb extract is prepared into medicines for reducing blood sugar or foods low in glycemic index through a preparation for controlling the postprandial blood sugar, the blood sugar controlling effects are notable, and the euryale ferox salisb extract is safe and does nothave any side effects.

Description

technical field [0001] The invention belongs to the technical field of extracting natural plant active components, and in particular relates to a Gorgon fruit extract used for postprandial blood sugar control, a preparation method and an application. Background technique [0002] In recent years, patients with hyperglycemia and diabetes have been increasing continuously and rapidly, and have become one of the major health problems of human beings. Studies have shown that the main feature of such patients is high blood sugar concentration, and high blood sugar is an important cause of diabetic complications. Therefore, controlling blood sugar concentration is very important for the prevention and treatment of this type of disease. In the early stage of type 2 diabetes, the first thing patients show is postprandial hyperglycemia, so how to control postprandial blood glucose has become the focus of attention. Carbohydrates such as starch are one of the main components in the h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/62A61P3/10A23L33/105A61K131/00
CPCA23V2002/00A61K36/62A61K2236/333A23L33/105A61P3/10A23V2200/328A23V2250/21
Inventor 尹忠平张丽陈继光上官新晨张清峰王梦曾嘉程刘媛沈倍韵周香菊
Owner JIANGXI AGRICULTURAL UNIVERSITY