Traditional Chinese medicine premix for preventing and treating diarrhea of rhizomyidae and preparation method of traditional Chinese medicine premix
A technology of premix and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine premix and its preparation for preventing and treating diarrhea in bamboo rats, which can solve problems such as health and safety hazards, antibiotic residues, drug resistance, etc., and achieve absorption promotion, low cost, and improved quality effect
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[0023] Such as figure 1 As shown, the preparation method of the traditional Chinese medicine premix for preventing and treating bamboo rat diarrhea provided by the embodiments of the present invention comprises the following steps:
[0024] S101: crush oregano, pass through a 100-mesh sieve, and place in supercritical CO 2 Extraction kettle; add 70%-80% ethanol and an equal volume of acetone that are 4 times the mass of oregano, the extraction temperature is 35°C-45°C, the pressure of the extraction kettle is 15MPa-20MPa, supercritical CO 2 The fluid flow rate is 20L / h, and the cycle extraction time is 1h to obtain oregano ointment, which is ready for use;
[0025] S102: Pulverize Pulsatillae, pass through a 80-mesh sieve; add chloroform with a volume fraction 8 times the mass of Pulsatillae, place in an ultrasonic cleaner for 30 minutes of ultrasonication; then transfer to a rotary evaporator, heat and reflux for extraction 3 times, and combine the 3 extractions solution, e...
Embodiment 1
[0031] The traditional Chinese medicine premix for preventing and treating bamboo rat diarrhea provided by the embodiment of the present invention consists of 8 parts by weight of oregano, 6 parts of striga, 8 parts of pulsatilla, 3 parts of Atractylodes macrocephala, 6 parts of gallinaceous root, and 6 parts of licorice And 0.5 parts of calcium bicarbonate.
[0032] The preparation method of the traditional Chinese medicine premix for preventing and treating bamboo rat diarrhea provided by the embodiments of the present invention comprises the following steps:
[0033] In the first step, the oregano is crushed, passed through a 100-mesh sieve, and placed in supercritical CO 2 Extraction kettle; add 70%-80% ethanol and an equal volume of acetone with 4 times the mass of oregano, the extraction temperature is 35°C, the pressure of the extraction kettle is 20MPa, supercritical CO 2 The fluid flow rate is 20L / h, and the cycle extraction time is 1h to obtain oregano ointment, whi...
Embodiment 2
[0038] According to the parts by weight, the traditional Chinese medicine premix for preventing and treating bamboo rat diarrhea is composed of 10 parts of oregano, 5 parts of striga, 6 parts of pulsatilla, 5 parts of Atractylodes macrocephala, 4 parts of gallinaceous root, and 4 parts of licorice and 1 part of calcium bicarbonate.
[0039] The preparation method of the traditional Chinese medicine premix for preventing and treating bamboo rat diarrhea provided by the embodiments of the present invention comprises the following steps:
[0040] In the first step, the oregano is crushed, passed through a 100-mesh sieve, and placed in supercritical CO 2 Extraction kettle; add 70%-80% ethanol and an equal volume of acetone with 4 times the mass of oregano, the extraction temperature is 45°C, the pressure of the extraction kettle is 15MPa, supercritical CO 2 The fluid flow rate is 20L / h, and the cycle extraction time is 1h to obtain oregano ointment, which is ready for use;
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