Use of pefloxacin in preparation of drugs for treatment and prevention of hyperlipidemia or atherosclerosis

A technology for atherosclerosis and pefloxacin, which is applied in the field of preparation of drugs for treating and preventing hyperlipidemia or atherosclerosis, and pefloxacin, can solve the problems of poor clostridium effect and the like, and achieve safety High, strong pharmacological effects, wide-ranging effects
CN110327340AInactive Publication Date: 2019-10-15CHENZHOU NO 1 PEOPLES HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHENZHOU NO 1 PEOPLES HOSPITAL
Publication Date
2019-10-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the field of biomedicine, and discloses a use of pefloxacin in the preparation of drugs for treatment and prevention of hyperlipemia or atherosclerosis. The pefloxacin can beprepared into any pharmaceutically acceptable preparation, and a new medical use of pefloxacin compounds is opened up, the current deficiencies in the drugs for the treatment and prevention of the hyperlipemia or the atherosclerosis are overcome, and a therapeutic role is achieved from anti-inflammatory and lipid-lowering ways; and meanwhile, the pefloxacin is a clinically verified broad-spectrumantibacterial drug, wide in source, low in price, high in pharmacological effect and high in safety, and belongs to the new use of old drugs, and an economical and safe drug choice is provided for themajority of patients with cardiovascular disease.
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Description

Technical field

[0001] The invention belongs to the field of biomedicine, and particularly relates to the use of pefloxacin in the preparation of drugs for treating and preventing hyperlipidemia or atherosclerosis. Background technique

[0002] Atherosclerosis (AS) is a common cardiovascular disease in modern society. It is mainly manifested as lipid deposition in the arterial intima, intimal fibrosis, and atherosclerotic plaque formation, which leads to hardening of the tube wall and lumen Stenosis, in turn, causes a series of secondary lesions, especially ischemic diseases in the cardiovascular and cerebrovascular areas, and is the number one killer of human beings in today's society.

[0003] The pathogenesis of atherosclerosis is complex, and hyperlipidemia and inflammation are considered to be the two most important pathogenic factors. The current main strategy for preventing and treating atherosclerosis is lipid-lowering. There are five commonly used lipid-lowering drugs: st...

Claims

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