Double-wall porous microcapsule probiotic sphere and preparation method thereof

Abstract

The invention relates to a double-wall porous microcapsule probiotic sphere and a preparation method thereof. A double wall layer self-assembled surface modification core material is adopted, an innerwall material is based on nano calcium carbonate and combined with ultrasonic oscillation to prepare porous hydrogel to increase capacity, so that a small part of the contiguous calcium carbonate isdispersed and loosened, agglomeration is avoided, and the probiotic load is significantly improved; an outer wall is coated with protein-polysaccharide compound gel, charge neutralization is driven byelectrostatic force to generate condensation, a compound with superior functional properties than proteins and polysaccharides is formed, thus the adsorption behavior of the proteins on an interfaceand rheological properties of an interfacial adsorption film are changed, microencapsulation of the wrapped core material is realized, and stability of a microcapsule is improved.

Description

technical field [0001] The invention belongs to the technical field of microcapsules, in particular to a double-wall porous microcapsule probiotic ball and a preparation method thereof. Background technique [0002] Bifidobacteria are the most important beneficial bacteria in the human intestinal tract, which is of great significance to maintaining the micro-ecological balance and normal physiological functions of the human intestinal tract and promoting human health. However, bifidobacteria are anaerobic bacteria and are not tolerant to strong acid environments. When they are taken orally into the human stomach, most of them are inactivated by gastric acid, bile and digestive enzymes, so it is difficult to effectively treat the human body. Therapeutic or health effects. [0003] Microencapsulated probiotics embedding technology is relatively practical at this stage, but there are still many difficult problems to overcome. Most of the microencapsulated probiotics on the ma...

AI Technical Summary

Problems solved by technology

Disadvantages: ①The nutritional environment of the core material is poor, and the reproduction rate of bifidobacteria is low; ②The single-layer wall is easily destroyed in the low-acid environment of the stomach, and a large number of probiotics are inactivated; ③The load of probiotics is small

Disadvantages: ①The nutritional environment of the core material is poor, and the reproduction rate of bifidobacteria is low; ②The single-layer wall is easily destroyed in the low-acid environment of the stomach, and a large number of probiotics are inactivated; ③The load of probiotics is small

Disadvantages: ① The elements and species of the bacterial culture solution are single, the bacterial flora has poor stress resistance, and the survival rate is low; ② The bacterial load in the capsule is small, and the effectiveness is reduced; ③ When the environmental pH changes, the gap between the wall gel and the gastrointestinal fluid The dissociation balance of the

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