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A dry chemical reagent strip for the detection of calcium, magnesium, zinc in breast milk

A technology for detecting reagents and dry chemistry, which is applied in the direction of material analysis by observing the influence of chemical indicators, analysis by making materials undergo chemical reactions, and measuring devices, which can solve complex production processes, high equipment prices, and testing time. Long and other problems, to achieve the effect of simple and convenient operation, low cost and short detection time

Active Publication Date: 2022-04-12
山东瑞思康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, ultrasonic infrared spectroscopy and liquid biochemical reagent method have problems such as high equipment price, professional operation, long test time and cumbersome test process, while dry chemical reagent method has the advantages of rapid detection, low cost and simple operation. , flexible, less test samples, accurate test results, short test time, etc.
[0004] At present, foreign companies use dry chemical reagents to detect many products (such as German MN company, ARKRAY Co., Ltd., and American Johnson & Johnson Group Co., Ltd.), which have complex production processes, high requirements for materials and equipment, and samples need Pretreatment requires professionals to operate, etc.
[0005] In addition, U.S. Patent US5968833 discloses a dry chemical test paper for measuring magnesium concentration in biological fluids, Chinese Patent CN98109147.4 discloses a breast milk calcium eye test strip and Chinese Patent CN20120130424.0 discloses a dry chemical test paper for calcium determination. The methods in these patents of the experimental piece are qualitative or quantitative to detect one item alone, and the detection item is single, and it is impossible to detect multiple items at the same time
U.S. Patent US3511608 discloses a method for preparing a multi-parameter rapid detection card for dairy products. This method has a relatively cumbersome test process, and the test sample needs to be pretreated once during the test. After the pretreatment, the test can be carried out, and the required sample high volume problem
At present, there is no dry chemical reagent strip that can be used for rapid detection of calcium ions, magnesium ions and zinc ions in breast milk at the same time

Method used

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  • A dry chemical reagent strip for the detection of calcium, magnesium, zinc in breast milk
  • A dry chemical reagent strip for the detection of calcium, magnesium, zinc in breast milk
  • A dry chemical reagent strip for the detection of calcium, magnesium, zinc in breast milk

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preparation example Construction

[0028] Preparation of the reaction layer: The reaction layer uses whatman filter paper as a carrier, with a pore size of 5um and a thickness of 50um. Take three whatman filter papers with a length*width of 20*20cm and immerse them in the calcium, magnesium, and zinc detection test paper reagents respectively. After 10 minutes, take it out immediately and put it in an oven at 60°C for drying. After 90 minutes, take it out, cut it into 5mm*5mm square pieces with a distance of 2mm, align and glue them together with double-sided tape, put them in an aluminum foil bag and seal them.

[0029] The formula of the calcium reaction reagent is as follows: oxalic acid 20g, 8-hydroxyquinoline 1.5g, arsenazo-III 1g, ethanol 8ml, polyethylene glycol 3g, glycerin 8ml, polyvinylpyrrolidone 0.5g, triton 0.1g, hydrochloric acid 0.5ml, purified water 600ml.

[0030] The formula of the magnesium reaction reagent is as follows: citric acid 15g, xylidine blue 2.1g, methanol 8.2ml, mannitol 6.5g, gly...

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Abstract

The invention provides a dry chemical reagent strip for simultaneous determination of calcium, magnesium, and zinc in breast milk, specifically, it is composed of a support layer and a detection reagent block; the detection reagent block is whatman filter paper that absorbs and detects calcium, magnesium, or zinc detection reagents , the detection reagent block is directly bonded to one end of the strip support layer. For specific use, hold the other end of the support layer, completely soak the detection reagent block in the sample to be tested (breast milk), take it out, and compare it with the standard color card after the color is stable. The dry chemical reagent strip provided by the invention can simultaneously detect the contents of calcium, magnesium and zinc without mutual influence or contamination of samples. The inspection process is efficient and simple, and the result data is reliable.

Description

technical field [0001] The invention relates to a technical field for rapid detection of calcium, magnesium and zinc, in particular to a detection reagent for breast milk calcium, magnesium and zinc and a dry chemical reagent strip for detection. Background technique [0002] Breast milk is the baby's natural nutrition. The composition of its milk directly affects the baby's growth and development, intellectual development and digestion ability, and it cannot be replaced by formula milk. The calcium, magnesium, and zinc content of breast milk nutrients are crucial to the growth and development of infants. Among them, calcium plays an important role in forming baby's bones and teeth, maintaining normal functions of nerves, blood, glands and heart. Zinc is an essential trace element for the human body. It is a component of various enzymes in the human body and has important physiological functions. It participates in protein synthesis in the body and promotes cell division, g...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/78
CPCG01N21/78G01N2021/7793G01N2021/7759
Inventor 毕世胤孙京花
Owner 山东瑞思康生物科技有限公司
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