Plant composition for reducing content of inflammatory cytokines TNF-alpha and IL-6 in tumor dyscrasia stage

Abstract

The invention relates to a plant composition, in particular to a plant composition for reducing the content of inflammatory cytokines tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) in a tumor dyscrasia stage and assisting in treating tumor dyscrasia. The plant composition comprises the following raw materials in parts by weight: 50 to 180 parts of germanium-rich barley seedlings,20 to 80 parts of herba houttuyniae, 30 to 100 parts of herba taraxaci, 20 to 60 parts of lemon, 60 to 120 parts of rhizoma polygonati, 10 to 50 parts of fructus alpiniae oxyphyllae, 5 to 40 parts ofcortex cinnamomi and 20 to 60 parts of herba cistanche. The plant composition disclosed by the invention can effectively reduce the overhigh content of the TNF-alpha and the IL-6 in the tumor dyscrasia stage, and solve the problems of malnutrition absorption, anorexia and emaciation caused by an inflammatory state.

Description

technical field [0001] The invention relates to a plant composition, in particular to a plant composition for reducing the content of inflammatory cytokines TNF-α and IL-6 in the stage of tumor cachexia. Background technique [0002] Cachexia is an inevitable stage in the development of most malignant tumors to the advanced stage. The probability of dyscrasia in advanced cancer patients is as high as 80%. The main cause of death in patients with advanced malignant tumors is closely related to cachexia. The main clinical manifestations are anorexia, lethargy, weight loss, anemia, and metabolic disorders of the three major nutrients (proteins, lipids, carbohydrates) and electrolyte disorders. The pathogenesis of cachexia is complex, and the exact mechanism is still unclear. Therefore, there is a lack of targeted and effective solutions in the treatment of cachexia. [0003] The medical community currently recognizes that systemic chronic inflammation and metabolic disorders p...

AI Technical Summary

Problems solved by technology

[0006] Medroxyprogesterone acetate is currently the most commonly used representative drug for the treatment of dyscrasia. Its shortcoming is that it mostly targets solid tumors and has no advantages in improving body weight, increasing nutrient absorption capacity, and reducing excessively high cytokine levels.

[0007] From the above analysis, although the mechanism of dyscrasia is complex, the exact mechanism is still unclear, and there is no effective treatment plan. However, for patients with emaciation, malabsorption and high levels of inflammatory cytokines, by reducing TNF- α, IL-6 levels, improving the inflammatory state of cachexia and improving nutrient absorption are important measures to relieve cancer pain and improve the quality of life of patients. At present, there are no relevant reports on how to reduce the levels of TNF-α and IL-6

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