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Polymer gel flexible film and visual detection method based on film for sweat glucose

A polymer gel flexible and flexible film technology, applied in analytical materials, measurement devices, chitin polysaccharide coatings, etc. The effect of health management, good biocompatibility, avoiding the fingertip blood collection process

Active Publication Date: 2020-02-07
杭州高斯博医疗用品有限公司 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, the most commonly used glucose sensors are mainly electrochemical systems, but electrochemical systems require complex circuits and signal conversion systems, and cannot achieve visual sensing effects. Horizontal continuous, visual, continuous monitoring, the present invention solves such problems

Method used

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  • Polymer gel flexible film and visual detection method based on film for sweat glucose
  • Polymer gel flexible film and visual detection method based on film for sweat glucose
  • Polymer gel flexible film and visual detection method based on film for sweat glucose

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Embodiment Construction

[0054] The present invention will be specifically introduced below in conjunction with the accompanying drawings and specific embodiments.

[0055] A polymer gel flexible film, the production process includes: preparing porous silicon / carbon quantum dot composite particles, and then preparing a chitosan film loaded with porous silicon / carbon quantum dot composite particles.

[0056] The preparation process of porous silicon / carbon quantum dot composite particles is as follows:

[0057] (1) Porous silicon particles with red fluorescent properties are obtained by electrochemically etching, electrochemically stripping, and weakly oxidizing the monocrystalline silicon wafer after surface washing and pretreatment;

[0058] The specific steps of electrochemical preparation of porous silicon particles are as follows: fix the P-type boron-doped silicon wafer in the electrolytic cell, add the organic solvent ethanol and hydrofluoric acid with a mass concentration of 40% as the electrol...

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Abstract

The invention discloses a polymer gel flexible film and a visual detection method based on the film for sweat glucose. A manufacturing process of the polymer gel flexible film includes the following steps: preparing porous silicon / carbon quantum dot composite particles, and preparing the porous silicon / carbon quantum dot composite particle-supported chitosan film to obtain the flexible film with two-color fluorescence properties. According to the method, the two-color fluorescence characteristics of the biological non-toxic porous silicon / carbon quantum dot composite material are used, the sensitivity of the fluorescent color of the particles in a glucose oxidase reaction system to a glucose concentration is used, a flexible natural polymer gel is used as a carrier to prepare the wearablesweat glucose detection film, the fluorescent color change of the material is used to continuously monitor the glucose level in sweat, so that the cumulative amount of the sweat glucose within a longperiod of time can be tested, timely early warning of high blood sugar is realized, the risk of missing changes in blood glucose peak values in a traditional blood glucose test is avoided, and the self-health management of patients with diabetes is facilitated.

Description

technical field [0001] The invention relates to the field of medical auxiliary detection, in particular to a polymer gel flexible film and a visual detection method for sweat glucose based on the film. Background technique [0002] Diabetes is the third chronic disease that seriously threatens human health after tumors and vascular lesions. If the blood sugar of diabetics exceeds the normal level, it will cause various complications and threaten the lives of patients. Therefore, in order to avoid the occurrence of hyperglycemia, frequent Blood glucose testing is an essential process in the daily life of people with diabetes. At present, most commercial blood glucose meters use acupuncture to take a 50 μL blood sample from the fingertip. The blood sample is inhaled by the disposable test strip on the blood glucose meter through chemical suction, and the blood glucose concentration is measured by the glucose electrochemical sensor. One blood glucose is measured each time. val...

Claims

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Application Information

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IPC IPC(8): C08J7/04C09D105/08C09D5/22C09D7/62G01N21/64C08L75/04
CPCC08J2375/04C08J2405/08C09D5/22C09D105/08C09D7/62C09D7/70G01N21/6428C08K9/02C08K7/26C08K3/04
Inventor 邬建敏崔瑶轩郑乐回
Owner 杭州高斯博医疗用品有限公司
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