Oral rehydration salt and preparation method thereof

Abstract

The invention discloses oral rehydration salt. The oral rehydration salt comprises 20-60 mM of sodium ions, 5-20 mM of potassium ions, 20-50 mM of chloride ions, 75-190 mM of glucose, 0-10 mM of calcium ions, 0-5 mM of magnesium ions, 0-10 mM of bicarbonate ions, and 2-10 mM of citrate ions. A preparation method of the oral rehydration salt comprises the following steps of: S1, respectively weighing the components including sodium chloride, potassium chloride, magnesium citrate, sodium citrate and calcium bicarbonate; S2, grinding the components, and filtering to ensure that the particle sizeof each component is 130-160 meshes; and S3, mixing the components, adding a dark berry extract, uniformly mixing, and packaging. The oral rehydration salt is suitable for Chinese physique, can quickly and effectively supplement water and electrolyte lost in the body under different mild and moderate dehydration conditions, can supplement several ions essential for the human body, and ensures thenormal electrolyte.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an oral rehydration salt and a preparation method thereof. Background technique [0002] 60% of the weight of the human body is water, and the normal physiological functions of the human body depend on the balance of water and its electrolytes (including sodium, potassium, chloride, magnesium, calcium, etc.). People can feel dry mouth when the water shortage reaches about 2% of body weight, and dehydration symptoms will appear if the water shortage reaches about 10%. If it continues, it will be life-threatening. In addition, human cell functions have certain requirements on electrolyte concentration, and severe electrolyte imbalance may lead to blood pressure drop, coma, circulatory failure and even death. The human body will lose a lot of body fluids (including water and electrolytes) in the case of diarrhea, vomiting and profuse sweating (in a high temperature environment or ...

AI Technical Summary

Problems solved by technology

However, this formula is mainly for acute dehydration caused by diseases (such as cholera), for dehydration caused by other reasons, it may cause hypernatremia

In addition, this formula is a single basic formula for the whole world, without taking into account the actual situation of each country

[0004] At present, there are 27 patents on oral rehydration salts or electrolyte beverages in China, among which 8 patents are developed on the basis of oral rehydration salt ORS III. Among them, CN102824362B has slightly changed the formula of ORS III, but the sodium and The proportion of potassium is too high; the formula of CN103610692B is exactly the same as that of ORS III; CN104258370A added zinc gluconate and protein tannin to the formula of ORS III in an attempt to repair the intestinal mucosa while replenishing water and electrolytes, and added artificial pigments Carmine and sweetener sucralose, these ingredients may have an impact on the absorption of electrolytes, while carmine and sucralose are potentially harmful; CN108597801A added vitamin C and probiotics on the basis of the ORS III formula, But these two components are not necessary to replenish water and electrolytes; CN1089045294A has changed the formula of ORSIII, the result is that the ratio of sodium to potassium is too low, the ratio of glucose to sodium is lower than 1:1, and the addition of zinc ions is not necessary electrolyte; CN109805236A added zinc ions on the basis of ORS III formula; CN109965172A added stachyose, lactic acid bacteria and fruit powder on the basis of ORS III formula, these are not necessary to replenish water and electrolytes, and may hinder Absorption of moisture and electrolytes; the formula of CN110496137A is completely consistent with ORSIII