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Compound medicine for improving gynecological reproductive endocrine diseases and preparation method of compound medicine

A technology for endocrine diseases and medicines, applied in the direction of medical preparations containing active ingredients, diseases, pharmaceutical formulas, etc., can solve the problems of unsatisfactory prevention or treatment effects, lack of improvement, etc., to avoid decoction and easy deterioration , Improve ovarian function and promote ovulation

Active Publication Date: 2020-08-28
THE OBSTETRICS & GYNECOLOGY HOSPITAL OF FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, Western medical treatment drugs lack the overall improvement effect on women's own reproductive system. Based on traditional Chinese medicine; , the kidney stores the essence, the essence can generate blood, the blood can transform the essence, the theory of "liver and kidney are of the same origin", the treatment can better regulate the internal environment of the body, thereby improving the development of the ovary and uterus
[0003] Based on the current situation that the current traditional Chinese medicine treatment is mostly limited to nourishing the kidney, and the effect of prevention or treatment is not satisfactory, the inventor of the present application intends to provide a Chinese medicine compound preparation that mainly focuses on nourishing the kidney, supplemented by soothing the liver, invigorating the spleen, and promoting blood circulation. A traditional Chinese medicine compound medicine for improving gynecological reproductive endocrine diseases and a preparation method thereof, the traditional Chinese medicine compound medicine is suitable for improving gynecological diseases caused by low endometrial receptivity, such as recurrent miscarriage, infertility, etc., and its curative effect is better

Method used

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  • Compound medicine for improving gynecological reproductive endocrine diseases and preparation method of compound medicine
  • Compound medicine for improving gynecological reproductive endocrine diseases and preparation method of compound medicine
  • Compound medicine for improving gynecological reproductive endocrine diseases and preparation method of compound medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030]Weigh the following raw materials: Cimicifuga 9g, Codonopsis 9g, Bupleurum 9g, Chishao 9g, Paeoniae Alba 9g, Raw Astragalus 15g, Salvia miltiorrhiza 15g, Rhizoma Chuanxiong 10g, Cortex paeonol 10g, Pueraria 10g, Cyperus cyperi 9g, Yanhu 9g, Toosendan 9g, Dodder 10g, Lingpi 10g, Chuan Duan or Eucommia 10g, Calamus 10g, Citrus aurantium 9g. After the raw materials are washed, add 6-8 times of the total amount of raw materials in distilled water, soak for 5-6 hours, after boiling with strong fire, switch to slow fire for 3-4 hours, and separate the decocted liquid; add 4-6 times of distilled water for the second time Distilled water, after boiling with strong fire, switch to slow fire for 2-3 hours, separate the decoction; add 2-3 times of distilled water for the third time, after strong fire boil, switch to slow fire for 1-2 hours, separate the decoction ; The three decoctions were combined, filtered, and concentrated to an extract with a relative density of 1.30-1.35g / ml....

Embodiment 2

[0032] Weigh the following raw materials: Cimicifuga 10g, Codonopsis 10g, Bupleurum 10g, Chishao 10g, Paeoniae Alba 10g, Raw Astragalus 23g, Salvia miltiorrhiza 23g, Chuanxiong 11g, Danpi 11g, Pueraria 11g, Rhizoma Cyperi 10g, Yanhu 10g, Toosendan 10g, Dodder 11g, Lingpi 11g, Chuan Duan or Eucommia 11g, Calamus 11g, Citrus aurantium 10g. After the raw materials are washed, add 6-8 times of the total amount of raw materials in distilled water, soak for 5-6 hours, after boiling with strong fire, switch to slow fire for 3-4 hours, and separate the decocted liquid; add 4-6 times of distilled water for the second time Distilled water, after boiling with strong fire, switch to slow fire for 2-3 hours, separate the decoction; add 2-3 times of distilled water for the third time, after strong fire boil, switch to slow fire for 1-2 hours, separate the decoction ; The three decoctions were combined, filtered, and concentrated to an extract with a relative density of 1.30-1.35g / ml. Add d...

Embodiment 3

[0034] Weigh the following raw materials: Cimicifuga 12g, Codonopsis 12g, Bupleurum 12g, Chishao 12g, Baishao 12g, Raw Astragalus 30g, Salvia miltiorrhiza 30g, Chuanxiong 12g, Danpi 12g, Pueraria 12g, Rhizoma Cyperi 12g, Yanhu 12g, Toosendan 12g, Dodder 12g, Lingpi 12g, Chuan Duan or Eucommia 12g, Calamus 12g, Citrus aurantium 12g. After the raw materials are washed, add 6-8 times of the total amount of raw materials in distilled water, soak for 5-6 hours, after boiling with strong fire, switch to slow fire for 3-4 hours, and separate the decocted liquid; add 4-6 times of distilled water for the second time Distilled water, after boiling with strong fire, switch to slow fire for 2-3 hours, separate the decoction; add 2-3 times of distilled water for the third time, after strong fire boil, switch to slow fire for 1-2 hours, separate the decoction ; The three decoctions were combined, filtered, and concentrated to an extract with a relative density of 1.30-1.35g / ml. Add dextrin...

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Abstract

The invention belongs to the field of traditional Chinese medicines and relates to a compound medicine for improving gynecological reproductive endocrine diseases. The compound medicine is prepared from active ingredients and medicinal auxiliary materials, wherein the active ingredients consist of raw material cimicifuga rhizome, codonopsis pilosula, radix bupleuri, radix paeoniae rubrathe, radixpaeoniae alba, raw radix astragali, radix salviae miltiorrhizae, rhizoma ligustici wallichii, cortex moutan, radix puerariae, rhizoma cyperi, rhizoma corydalis, fructus toosendan, semen cuscutae, herba epimedii, dipsacus root or eucommia bark, acorus calamus and fructus aurantii. The compound medicine is prepared into granules, and animal experiments prove that the compound medicine can improve the thickness of endometrium and gland development of the mouse, improve the endometrial receptivity and regulate the HPO axis, and is suitable for improving gynecological diseases, such as recurrent abortion, infertility and the like, caused by low endometrial receptivity. The compound medicine can avoid inconvenience of temporary decoction and easy deterioration before the traditional Chinese medicine decoction is taken, and is convenient for patients.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and specifically relates to a compound traditional Chinese medicine for improving gynecological reproductive endocrine diseases and a preparation method thereof. The compound traditional Chinese medicine is suitable for improving gynecological diseases caused by low endometrial receptivity, such as recurrent miscarriage, infertility etc. Background technique [0002] The prior art discloses that in the 21st century, human beings have increasing demands on health, especially reproductive health, and reproductive health has increasingly become a focus of international attention. According to statistics, the probability of a woman of normal childbearing age successfully conceiving in one menstrual cycle is only about 30%. Although the global population is still increasing rapidly and is expected to exceed 9 billion by 2050, there are still couples unable to conceive due...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P15/00A61P15/06A61P15/08
CPCA61K36/71A61K36/344A61K36/233A61K36/65A61K36/481A61K36/537A61K36/236A61K36/488A61K36/8905A61K36/66A61K36/58A61K36/39A61K36/43A61K36/296A61K36/185A61K36/46A61K36/888A61K36/752A61P15/00A61P15/06A61P15/08A61K2300/00
Inventor 王凌张娜李丽莎邱学敏潘心瑶陈力嘉周璟李楚宇黄锃恕梁颖婷
Owner THE OBSTETRICS & GYNECOLOGY HOSPITAL OF FUDAN UNIV
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