Unlock instant, AI-driven research and patent intelligence for your innovation.

Isovitexin-2'-O-beta-D-glucopyranoside, preparation method and application thereof

A technology of glucopyranoside and isovitexin, which is applied in the field of isovitexin-2″-O-β-D-glucopyranoside, achieves the advantages of less environmental pollution, cheap and easily available raw materials, and broad application prospects. Effect

Active Publication Date: 2020-09-04
广西资源黄精生物科技有限公司
View PDF6 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, there is currently no report of isovitexin-2″-O-β-D-glucopyranoside isolated from the aerial or underground parts of Rhizoma Polygonatum

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Isovitexin-2'-O-beta-D-glucopyranoside, preparation method and application thereof
  • Isovitexin-2'-O-beta-D-glucopyranoside, preparation method and application thereof
  • Isovitexin-2'-O-beta-D-glucopyranoside, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] The preparation method of the isovitexin-2″-O-β-D-glucopyranoside of the present embodiment comprises the following steps:

[0082] Step 1: Prepare the Water Extraction Solution

[0083] Take 1.5kg of fresh Rhizoma Rhizoma Polygonatum as a raw material, wash it, and chop it into 2cm-3cm.

[0084] Add 8 times the weight of the raw material in an aqueous ethanol solution with a volume concentration of 80%, extract at 50°C for 4 hours, and filter for the first time to obtain the first filtrate and the first filter residue; add 8 times the weight of the raw material in the first filter residue Concentration is 80% ethanol aqueous solution, extract 4h at 50 ℃, filter for the second time, get the second filtrate and the second filter residue; add raw material 8 times weight in the second filter residue and the volume concentration is 80% ethanol aqueous solution , Extracted at 50°C for 4h, and filtered for the third time to obtain the third filtrate.

[0085] The first filt...

Embodiment 2

[0109] The preparation method of the isovitexin-2″-O-β-D-glucopyranoside of the present embodiment comprises the following steps:

[0110] Step 1: Prepare the Water Extraction Solution

[0111] Take 1.5kg of fresh Rhizoma Polygonatum Diannian aboveground stems and leaves as raw materials, wash and chop into 2cm-3cm.

[0112] Add 10 times the weight of the raw material in a methanol aqueous solution with a volume concentration of 60%, extract at room temperature for 3 days, and filter for the first time to obtain the first filtrate and the first filter residue; add 10 times the volume concentration of the raw material to the first filter residue It is 60% aqueous methanol solution, extracted at room temperature for 3 days, and filtered for the second time to obtain the second filtrate and the second filter residue; in the second filter residue, add 10 times the weight of the raw material in the methanol aqueous solution with a volume concentration of 60%. Extract at room tempe...

Embodiment 3

[0132]The preparation method of the isovitexin-2″-O-β-D-glucopyranoside of the present embodiment comprises the following steps:

[0133] Step 1: Prepare the Water Extraction Solution

[0134] Take 1.5Kg fresh leaves of Polygonatum polyflora above the ground as raw material, wash and chop into 2cm-3cm.

[0135] Add 15 times the weight of the raw material in an aqueous ethanol solution with a volume concentration of 10%, use a power of 100W, and a frequency of 40kHz for ultrasonic extraction for 0.5h, and filter for the first time to obtain the first filtrate and the first filter residue; in the first filter residue Add 15 times the weight of the raw material in an aqueous acetone solution with a volume concentration of 10%, use a power of 100W, and a frequency of 40kHz for ultrasonic extraction for 0.5h, and filter for the second time to obtain the second filtrate and the second filter residue; in the second filter residue Add 15 times the weight of the raw material in an aqu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses an isovitexin-2'-O-beta-D-glucopyranoside, a preparation method and application thereof, and belongs to the technical field of extraction, separation and purification of traditional Chinese medicine components. The preparation method of the isovitexin-2'-O-beta-D-glucopyranoside comprises the following steps: step 1: preparing water extraction solution; step 2: preparing C-glycosylflavone fraction; step 3: preparing isovitexin-2'-O-beta-D-glucopyranoside monomer fraction; and step 4: preparing isovitexin-2'-O-beta-D-glucopyranoside. The invention also discloses the isovitexin-2'-O-beta-D-glucopyranoside and application. According to the present invention, the aerial parts of polygonatum are used as raw materials for the first time, high-content and high-purity isovitexin-2'-O-beta-D-glucopyranoside is obtained quickly, and a new way is provided for comprehensive development and deep utilization of polygonatum plant resources.

Description

technical field [0001] The invention relates to isovitexin-2″-O-β-D-glucopyranoside, its preparation method and application, and belongs to the technical field of extraction, separation and purification of traditional Chinese medicine components. Background technique [0002] Carbon glycoside flavonoids refer to the sugar groups directly connected to the flavonoid aglycone by C-C bond, the structure is stable and not easy to be hydrolyzed. These compounds have strong biological activities such as anti-oxidation, anti-radiation, hypoglycemic, antibacterial and antiviral. Such compounds are naturally low-toxic and have a wide range of pharmacological activities, and have attracted more and more attention. [0003] Isovitexin-2″-O-β-D-glucopyranoside is a carbon glycoside flavonoid compound. There is no hydroxyl group on the C ring of this compound and the hydrogen at the 6th position on the A ring is replaced by glucose to form C-flavone glycosides This compound has a strong...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07H17/04C07H1/08A61K31/7048A61P3/04A61K8/60A61Q19/06A23L33/105A23L33/125
CPCA23V2002/00A61K8/602A61Q19/06A23L33/105A23L33/125A61P3/04C07H1/08C07H17/04A23V2200/332A23V2250/21A23V2300/14
Inventor 王亚凤黄永林何瑞杰阳丙媛
Owner 广西资源黄精生物科技有限公司