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Whitening anti-inflammatory composition, and application and preparation method thereof

An anti-inflammatory composition and whitening technology, applied in the field of skin care products, can solve the problems of damaged skin stratum corneum, limited whitening effect, prone to redness, swelling, allergies, etc., and achieve excellent whitening, brightening, and good mechanical stability effects

Inactive Publication Date: 2020-09-08
烟台仙瑟商贸有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the current whitening products on the market are difficult to penetrate into the basal layer of the skin epidermis, and the whitening effect is limited. It is often necessary to add a large amount of penetrating agent to promote skin absorption, or add fruit acid and keratinase to accelerate the exfoliation of the stratum corneum to improve the whitening effect of the product
However, the use of excessive chemical penetrants, fruit acids, and keratinases often damages the stratum corneum of the skin, making the skin sensitive and fragile, and prone to redness, swelling, allergies and other skin inflammations

Method used

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  • Whitening anti-inflammatory composition, and application and preparation method thereof
  • Whitening anti-inflammatory composition, and application and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0096] Example 1 provides an essence prepared from a whitening and anti-inflammatory composition, which includes, by weight, 0.6 parts of Siberia chinensis extract, 3.0 parts of tranexamic acid, 5.66 parts of skin conditioning agents, 1.0 parts of moisturizing agents, 0.1 part of Carbomer U20, 0.02 part of disodium EDTA, 0.11 part of sodium citrate, 1.5 parts of dimethyl isosorbide, 70.0 parts of water, 6.0 parts of methylpropanediol, 12.0 parts of 1,3-propanediol.

[0097] The skin conditioning agent is a combination of arginine, acetyl tetrapeptide-11, nicotinamide and 1,2-hexanediol, and the weight ratio of the four is 1:0.55:20:35. The moisturizing agent is a combination of mannitol, sodium hyaluronate, and hydrolyzed hyaluronic acid, and the weight ratio of the three is 1:0.6:0.4; the sodium hyaluronate is purchased from HA-LQSH of Kewpie Corp., Japan, The molecular weight is 1.2 to 2.2 million (the average molecular weight is 1.7 million); the hydrolyzed hyaluronic acid ...

Embodiment 2

[0101] Example 2 provides an essence prepared from a whitening and anti-inflammatory composition, which includes, by weight, 0.33 parts of Radix chinensis extract, 0.67 parts of tranexamic acid, 2 parts of skin conditioning agents, 0.5 parts of moisturizing agents, 0.05 parts of Carbomer U20, 0.01 parts of disodium EDTA, 0.05 parts of sodium citrate, 1 part of dimethyl isosorbide, 62.0 parts of water, 6.0 parts of methylpropanediol, 12.0 parts of 1,3-propanediol.

[0102] The skin conditioning agent is a combination of arginine, acetyl tetrapeptide-11, nicotinamide and 1,2-hexanediol, and the weight ratio of the four is 1:0.1:15:30. The moisturizing agent is a combination of mannitol, sodium hyaluronate, and hydrolyzed hyaluronic acid, and the weight ratio of the three is 1:0.4:0.2; the sodium hyaluronate is purchased from HA-LQSH of Kewpie Corp. in Japan, The molecular weight is 1.2 to 2.2 million (the average molecular weight is 1.7 million); the hydrolyzed hyaluronic acid i...

Embodiment 3

[0105] Example 3 provides an essence prepared from a whitening and anti-inflammatory composition, which includes, by weight, 0.4 parts of Siberia chinensis extract, 4.6 parts of tranexamic acid, 8 parts of skin conditioning agents, 2 parts of moisturizing agents, 0.2 parts of Carbomer U20, 0.05 parts of disodium EDTA, 0.2 parts of sodium citrate, 2 parts of dimethyl isosorbide, 82.0 parts of water, 6.0 parts of methyl propylene glycol, 12.0 parts of 1,3-propanediol.

[0106] The skin conditioning agent is a combination of arginine, acetyl tetrapeptide-11, nicotinamide and 1,2-hexanediol, and the weight ratio of the four is 1:1:25:40. The moisturizing agent is a combination of mannitol, sodium hyaluronate, and hydrolyzed hyaluronic acid, and the weight ratio of the three is 1:0.8:0.4; the sodium hyaluronate is purchased from HA-LQSH of Kewpie Corp., Japan, The molecular weight is 1.2 to 2.2 million (the average molecular weight is 1.7 million); the hydrolyzed hyaluronic acid is...

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Abstract

The invention discloses a whitening anti-inflammatory composition. The whitening anti-inflammatory composition comprises a siegesbeckia orientalis extract and tranexamic acid, wherein the weight ratioof the siegesbeckia orientalis extract to the tranexamic acid is 1:(2-12). Essence prepared from the whitening anti-inflammatory composition meets the requirements on the content of microorganisms and the content of lead, mercury, cadmium, arsenic, phenol, hydroquinone and dioxane in (Safety and Technical Standards for Cosmetics 2015). Through a skin closed type photopatch test, no adverse skin reaction is caused, and whitening anti-inflammatory composition has good mechanical stability, has excellent whitening, brightening, anti-inflammatory, soothing and repairing functions, and does not cause adverse reactions such as redness, swelling and allergy.

Description

technical field [0001] The invention belongs to the field of skin care products, and more specifically, the invention relates to a whitening and anti-inflammatory composition and its application and preparation method. Background technique [0002] Melanin is a protein that exists in the basal layer of everyone's skin. After being irradiated by ultraviolet rays, it will change and produce a substance that protects the skin; then melanin moves to the epidermis layer by layer through cell metabolism, resulting in dark complexion, Skin problems such as dark spots and uneven skin tone. With the improvement of people's consumption level, more and more consumers begin to apply whitening skin care products daily to inhibit the generation and migration of melanin. [0003] However, the current whitening products on the market are difficult to penetrate into the basal layer of the skin epidermis, and the whitening effect is limited. It is often necessary to add a large amount of pen...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/44A61K8/34A61K8/73A61Q19/02A61P29/00
CPCA61K8/345A61K8/44A61K8/735A61K2800/592A61K2800/72A61Q19/02A61K8/9789A61P29/00
Inventor 薛永红
Owner 烟台仙瑟商贸有限公司
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