Novel PTCA balloon catheter

A balloon catheter, a new type of technology, applied in balloon catheters, catheters, coatings, etc., can solve the problems of poor hydrophilicity, insufficient biocompatibility and stability, poor comfort, etc., to improve compatibility, Improve biocompatibility and improve hydrophilicity

Inactive Publication Date: 2020-12-01
浙江桐轩医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing balloon catheter has insufficient biocompatibility and stability, and the existing

Method used

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  • Novel PTCA balloon catheter
  • Novel PTCA balloon catheter
  • Novel PTCA balloon catheter

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0069] As a preferred technical scheme, the preparation method of the hydrophilic coating at least includes the following steps:

[0070] (1) placing the balloon with a compatible layer and an antiproliferative drug layer in the mold;

[0071] (2) Add antibacterial agent and solvent in mold and stir to obtain composite liquid A;

[0072] (3) Adding the hydrophilic agent and the modified cellulose into the mold and mixing them with the composite liquid A, and performing repeated freeze-thaw treatments to form a hydrophilic coating and then dry it.

[0073] As a preferred technical solution, the material of the balloon 3 is at least one selected from nylon, polyvinyl chloride, ethylene, polyurethane, polyether block amide copolymer and polyethylene terephthalate.

[0074] As a preferred technical solution, the material of the balloon 3 is polyethylene terephthalate.

[0075] In addition, all raw materials used are commercially available unless otherwise stated.

Embodiment 1

[0077] see Figure 1-3 , a PTCA balloon catheter is provided in this embodiment, comprising a distal tube 1, a proximal tube 2 and a balloon 3, the bottom end of the distal tube 1 is provided with a proximal tube 2, and the proximal tube The outside of the balloon 2 is covered with a balloon 3, and the balloon 3 is provided with three layers from the inside to the outside, including a compatible layer 6, an anti-proliferation drug layer 5 and a hydrophilic coating 4.

[0078]The balloon 3 is formed in the shape of a hollow bag, the middle portion thereof is formed in a cylindrical shape, and both ends thereof are tapered to form a tapered shape. The balloon 3 does not have to be made of a single material, but can be a double layer comprising different materials between the inner and outer layers. A bilayer balloon can be manufactured by forming a tube produced by bilayer extrusion.

[0079] In this embodiment, the inner wall of the balloon 3 is provided with an inner flow la...

Embodiment 2

[0082] This embodiment provides a new type of balloon catheter, which differs from Embodiment 2 in that the mass ratio among the compatible layer, the anti-proliferative drug layer and the hydrophilic coating is 1:1:1. The material of the compatible layer is biocompatible material. The compatibility layer is a mixture of ethylene-vinyl acetate copolymer and polyethylene. The weight ratio of the ethylene-vinyl acetate copolymer to polyethylene is 5:1, and the melt index of the ethylene-vinyl acetate is 25g / 10min. D1238 test method is obtained, and the trade mark of described ethylene-vinyl acetate copolymer is: Beijing Organic Y3200. The melt index of the polyethylene is 1.9g / 10min. The melt index is obtained by the ISO1133 test method at 190°C and 2.16kg. The grade of the polyethylene is: China Sea Shell 2420H.

[0083] The preparation method of the compatible layer is that the mixture of ethylene-vinyl acetate copolymer and polyethylene is melted, and then coated on the sur...

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Abstract

The invention provides a novel PTCA balloon catheter. The catheter comprises a far-end tube, a near-end tube and a balloon, a near-end tube is arranged at the bottom end of the far-end tube, the balloon sleeves the outside of the near-end tube, the balloon is provided with three layers and comprises a hydrophilic coating, a compatibility layer and an anti-proliferative drug layer, an inner flow layer and an outer flow layer are arranged on the inner wall of the balloon, the inner flow layer is attached to the outer flow layer, the inner flow layer is formed by staggered limiting slim tubes, and the outer flow layer is formed by a fine hair structure. The PTCA balloon catheter adopts the hydrophilic coating, the compatibility layer and the anti-proliferative drug layer to improved the intermiscibility of organisms; and during the flow process, a liquid flows into the inner flow layer from the outer flow layer, the fusion of the liquid is improved by a plurality of groups of the limitingslim tubes, so that the biocompatibility of organisms can be greatly improved; the biological liquid flows to the outer flow layer after being dissolved, and the liquid tends to be stable after beingfused due to the action of a plurality of fine hairs; and in addition, the compatibility of the liquid can be further improved due to the action of the fine hairs.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a novel PTCA balloon catheter. Background technique [0002] PTCA is the abbreviation for Percutaneous Transluminal Coronary Angioplasty. The term PTCA broadly covers all interventional methods for coronary heart disease. However, in a narrow sense, people often refer to traditional balloon dilation of coronary artery. Balloon dilation is the basis of all interventional treatment techniques for coronary heart disease. Use antiplatelet drugs. The existing balloon catheter has insufficient biocompatibility and stability, and the existing balloon catheter has poor hydrophilicity, which will lead to poor comfort of the human body when used in the body. [0003] Therefore, how to design a new type of PTCA balloon catheter has become a problem to be solved at present. Contents of the invention [0004] In order to solve the above-mentioned technical problems, the present ...

Claims

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Application Information

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IPC IPC(8): A61L29/08A61L29/16A61L29/14A61L29/06A61M25/10
CPCA61L29/06A61L29/085A61L29/14A61L29/16A61L2300/23A61L2300/416A61L2300/602A61L2300/606A61L2400/18A61L2420/08A61M25/104A61M2025/105A61M2025/1075C08L23/12C08L1/284C08L23/06C08L29/04C08L31/04C08L67/04
Inventor 沈坤
Owner 浙江桐轩医疗科技有限公司
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