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Emamectin benzoate nano capsule and preparation method thereof

A technology of methylamino abamectin and nano-capsules, applied in the field of pesticides, can solve the problems of harsh manufacturing conditions, inability to give full play to its own advantages, short efficacy of methylamino abamectin benzoate, etc. High coverage, improved photolysis resistance and utilization, improved efficacy and duration of efficacy

Inactive Publication Date: 2020-12-22
HUIZHOU YINNONG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, emamectin benzoate product formulations in the market are mainly emulsifiable concentrates, microemulsions and water-dispersible granules, but emamectin benzoate is prone to photolysis
During the use of the emamectin benzoate of the above dosage form, the emamectin benzoate will be exposed to the external environment, and the emamectin benzoate will be exposed to light, air, The influence of environmental factors such as rainwater will cause the problems of short efficacy and low utilization rate of emamectin benzoate
At the same time, emamectin benzoate is insoluble in water, resulting in its own advantages cannot be fully utilized, which limits the wide application of emamectin benzoate to a certain extent
[0005] At this stage, there are many methods for emamectin benzoate to resist photolysis and improve drug efficacy, such as microencapsulation, anti-photolysis nano-preparation, use of protective materials such as hollow mesoporous materials, and the use of emamectin Modification and optimization of the structure of vermectin benzoate itself, etc., but most of them require harsh manufacturing conditions, complicated processes or high costs

Method used

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  • Emamectin benzoate nano capsule and preparation method thereof
  • Emamectin benzoate nano capsule and preparation method thereof
  • Emamectin benzoate nano capsule and preparation method thereof

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preparation example Construction

[0064] In order to better understand the emamectin benzoate nanocapsules of the present invention, the application also provides a preparation method of emamectin benzoate nanocapsules. The preparation method of above-mentioned emamectin benzoate nanocapsules comprises the steps: placing emamectin benzoate and emulsifier in a solvent and carrying out the first mixing operation to form an emulsion; The monobasic acid and the carrier material are placed in water for a second mixing operation to form a second-phase solution; the cross-linking agent is placed in water to form a third-phase solution; the first-phase solution and the second-phase solution are subjected to a fourth mixing operation, Obtain the mixed solution; carry out the fifth mixing operation to the mixed solution and the third phase solution to obtain emamectin benzoate nanocapsules.

[0065] The preparation method of above-mentioned emamectin benzoate nanocapsules is simple, easy to operate, preparation conditio...

Embodiment 1

[0089] Emamectin benzoate nanocapsules include:

[0090]The first phase solution: emamectin benzoate 10g, chain fatty alcohol polyoxyethylene ether 10g and alcohol ethers 40g;

[0091] Second phase solution: hydrochloric acid 10g, chitosan 0.5g and water 7.0kg;

[0092] The third phase solution: Potassium polyphosphate 0.1g and water 2.8kg.

Embodiment 2

[0094] Emamectin benzoate nanocapsules include:

[0095] The first phase solution: emamectin benzoate 50g, polyoxyethylene fatty acid ester 40g, calcium dodecylbenzenesulfonate 10g and ketone solvent 200g;

[0096] Second phase solution: hydrochloric acid 10g, potassium chloride 1g, chitosan 2g and water 6.9kg;

[0097] The third phase solution: potassium tripolyphosphate 0.1g, potassium chloride 1g and water 2.7kg

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Abstract

The invention provides an emamectin benzoate nano-capsule and a preparation method of the emamectin benzoate nano-capsule. The emamectin benzoate nano-capsule is prepared from the following componentsin parts by weight: 0.1 to 6 parts of emamectin benzoate, 0.1 to 18 parts of emulsifier, 0.4 to 25 parts of solvent, 0.1 to 1 part of monobasic acid, 0.005 to 2 parts of carrier material, 0.001 to 1part of cross-linking agent and 45 to 98 parts of water. The emamectin benzoate nano-capsule is lasting in drug effect, and the utilization rate of emamectin benzoate is increased.

Description

technical field [0001] The invention relates to the technical field of pesticides, in particular to a emamectin benzoate nanocapsule and a preparation method thereof. Background technique [0002] In the context of growing and diversifying food demand, my country's Ministry of Agriculture and Rural Affairs has proposed the ambitious goal of "zero growth in pesticide use". The key to achieving this goal is to improve the efficacy and utilization of pesticides. [0003] Emamectin benzoate is a biological pesticide ingredient, a new type of high-efficiency semi-synthetic antibiotic insecticide synthesized from the fermented product abamectin B1. Emamectin benzoate is used to kill insects by means of contact and stomach poisoning, and is now widely used on vegetables, fruit trees, cotton and other crops, and has good insecticidal activity on crops, especially for Lepidoptera Insect larvae and mite pests. [0004] Currently on the market, emamectin benzoate product formulation...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N25/28A01N25/32A01N43/90A01P7/04
CPCA01N25/28A01N25/32A01N43/90
Inventor 刘润儒吴丽文廖联安
Owner HUIZHOU YINNONG TECH
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