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Dressing for promoting wound healing of burns and scalds and preparation method thereof

A wound healing, burn and scald technology, applied in the direction of medical science, bandages, etc., can solve the problems of not being able to effectively promote wound healing, not having wound healing, and affecting the appearance of the skin, so as to promote scab healing, promote wound healing, improve The effect of osmosis

Active Publication Date: 2021-02-12
问兰药业(苏州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many problems in the use of current medical dressings
[0003] Wound healing is a complex process, but general dressings do not have the effect of promoting wound healing
In the process of use, it cannot effectively promote the healing of the wound surface, resulting in a long course of disease for the patient, increasing the burden on the patient, and prone to scarring, which affects the appearance of the skin, or easily adheres to the wound to cause secondary trauma, and damages the new tissue when it is removed. patients in great pain
A large number of various burn and scald dressings are emerging on the market at present, such as animal collagen, chitosan, and hyaluronic acid are all commonly used raw materials for burn and scald dressings, and the prepared burn and scald dressings cannot solve the above problems well

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A dressing for promoting the healing of burns and scalds, which is composed of the following raw materials in parts by weight: 20 parts of polyvinylpyrrolidone, 5 parts of caffeic acid-4-3-hydroxypropylmorpholine ester, 7 parts of glutathione, and chlorella 0.7 parts of extract, 0.2 parts of L-lactic acid, 1 part of asiaticoside, 0.5 parts of nicotinic acid inositol, 0.8 parts of hydroxyethyl urea, 0.5 parts of laurocapram, 2 parts of cellulose nitrate, 3 parts of borneol, hydrogenated 3 parts of lecithin, 45 parts of purified water.

[0027] The preparation method of the above-mentioned dressing for promoting burn and scald wound healing may further comprise the steps:

[0028] (1) Take purified water accounting for half of the total amount, and dissolve polyvinylpyrrolidone in purified water with a temperature ≥ 90°C;

[0029] (2) Take the remaining purified water, add caffeic acid-4-3-hydroxypropyl morpholine ester, glutathione, chlorella extract, L-lactic acid, asi...

Embodiment 2

[0032] A dressing for promoting the healing of burns and scald wounds, which consists of the following raw materials in parts by weight: 17 parts of polyvinylpyrrolidone, 2 parts of caffeic acid-4-3-hydroxypropylmorpholine ester, 5 parts of glutathione, and chlorella 0.5 parts of extract, 0.3 parts of L-lactic acid, 0.5 parts of asiaticoside, 0.4 parts of nicotinic acid inositol, 0.5 parts of hydroxyethyl urea, 0.35 parts of laurocapram, 1.5 parts of cellulose nitrate, 2 parts of borneol, hydrogenated 1 part of lecithin, 40 parts of purified water.

[0033] The preparation method of the above-mentioned dressing for promoting burn and scald wound healing may further comprise the steps:

[0034] (1) Take purified water accounting for half of the total amount, and dissolve polyvinylpyrrolidone in purified water with a temperature ≥ 90°C;

[0035] (2) Take the remaining purified water, add caffeic acid-4-3-hydroxypropyl morpholine ester, glutathione, chlorella extract, L-lactic a...

Embodiment 3

[0038] A dressing for promoting the healing of burns and scalds, which is composed of the following raw materials in parts by weight: 23 parts of polyvinylpyrrolidone, 8 parts of caffeic acid-4-3-hydroxypropylmorpholine ester, 10 parts of glutathione, and chlorella 0.8 parts of extract, 0.5 parts of L-lactic acid, 1.2 parts of asiaticoside, 0.8 parts of nicotinic acid inositol, 1 part of hydroxyethyl, 0.7 parts of laurocapram, 3 parts of cellulose nitrate, 5 parts of borneol, hydrogenated eggs 4 parts of phospholipids, 50 parts of purified water.

[0039] The preparation method of the above-mentioned dressing for promoting burn and scald wound healing may further comprise the steps:

[0040] (1) Take purified water accounting for half of the total amount, and dissolve polyvinylpyrrolidone in purified water with a temperature ≥ 90°C;

[0041] (2) Take the remaining purified water, add caffeic acid-4-3-hydroxypropyl morpholine ester, glutathione, chlorella extract, L-lactic aci...

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PUM

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Abstract

The invention discloses a dressing for promoting wound healing of burns and scalds. The composition is prepared from the following raw materials in parts by weight: 17-23 parts of polyvinylpyrrolidone, 2-8 parts of caffeic acid-4-3-hydroxypropyl morpholine ester, 5-10 parts of glutathione, 0.5-0.8 part of chlorella extract, 0.3-0.5 part of L-lactic acid, 0.5-1.2 parts of asiaticoside, 0.4-0.8 partof inositol nicotinate, 0.5-0.7 part of hydroxyethyl urea, 0.35-0.7 part of laurocapram, 1.5-3 parts of a film-forming agent, 2-5 parts of borneol, 1-4 parts of hydrogenated lecithin and 40-50 partsof purified water. According to the dressing provided by the invention, polyvinylpyrrolidone is used as a matrix, and caffeic acid-4-3-hydroxypropyl morpholine ester and glutathione are added to promote rapid healing of burn and scald wounds. The chlorella extract and the L-lactic acid can regulate and control synthesis of collagen at the wound surface, the inositol nicotinate can relieve edema atthe burn and scald wound surface, and the asiaticoside and the hydroxyethyl urea can prevent the dressing and the wound surface from adhering to damage new tissues. The invention also provides a preparation method of the dressing for promoting wound healing of burns and scalds, the preparation process is simple and easy to operate, and commercial production and application are facilitated.

Description

technical field [0001] The invention relates to the field of medical dressings, in particular to a dressing for promoting burn and scald wound healing and a preparation method thereof. Background technique [0002] Burns and scalds are a kind of injury that people encounter in work and life. In real life, burns and scalds occur from time to time. After being burned or scalded, the skin of the burned or scalded area will become red and blistered, and the edema will be severe. fester. Improper treatment of wounds often leads to scarring, affecting the appearance, and even causing lifelong physical and mental damage. Typically, burn ointment or dressings are applied to the wound. Medical dressing is a kind of medical material used to temporarily cover the surface of various burns and scald wounds, which can protect the wound from bacterial infection and other external factors, and play a role in protecting the wound and the wound surface. A traditional dressing is generally ...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0057A61L26/0061A61L26/0066A61L2300/216A61L2300/252A61L2300/30A61L2300/412C08L39/06
Inventor 李晓鹏
Owner 问兰药业(苏州)有限公司
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