Tibetan medicine toothpaste and preparation method thereof
A technology of Tibetan medicine and toothpaste, applied in the fields of pharmaceutical formulation, dentistry, medical science, etc., can solve the problems of insignificant improvement of oral microbial environment, unfavorable oral self-repair and maintenance, etc., to achieve self-repair and balance, double layer The effect of repairing and maintaining oral health and improving results
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Embodiment 1
[0024] Embodiment 1: a kind of Tibetan medicine toothpaste includes Tibetan medicine water extract, cold water stone and auxiliary agent; Said Tibetan medicine water extract is Saffron, ginger, Cordyceps sinensis, Tibetan snow lotus, Tangut rhubarb combined in proportion, carried out in water water extraction, and then filter the Tibetan medicine aqueous extract;
[0025] Preferably, saffron 10-15g, ginger 8-12g, cordyceps sinensis 1-3g, Tibetan snow lotus 1-5g, Tangut rhubarb 1-4g, cold water stone 5-10g; the auxiliary agent includes 15-40g of friction agent , Adhesive 1-4g, preservative 0.05-0.3g, surfactant 0.5-5g, wetting agent 7-45g, flavor enhancer 0.05-1.3g;
[0026] Preferably, the friction agent is one or a combination of calcium carbonate and hydrated silicic acid;
[0027] Preferably, the binder is one or a combination of sodium alginate and guar gum;
[0028] Preferably, the preservative is potassium sorbate;
[0029] Preferably, the surfactant is sodium lauryl ...
Embodiment 2
[0040] Embodiment 2: antibacterial experiment
[0041] Experimental group 1: The preparation method in Example 1 was used to prepare Tibetan medicine toothpaste, wherein the contents of each component were: 10g of saffron, 9g of ginger, 1.2g of Cordyceps sinensis, 2.5g of Tibetan snow lotus, 1g of Tangut rhubarb, 7.5g of Hanshui stone, hydration Silica 20g, sodium alginate 2.5g, potassium sorbate 0.05g, sodium lauryl sulfate 1g, sorbitol 10g, menthol 0.08g, peppermint oil 0.03g.
[0042]Experimental group 2: Tibetan medicine toothpaste was prepared by the same preparation method as experimental group 1, wherein the contents of each component were: 12g of saffron, 8g of ginger, 1g of Cordyceps sinensis, 2g of Tibetan snow lotus, 1g of Tangut rhubarb, 6g of cold water stone, and 15g of hydrated silica , sodium alginate 2g, potassium sorbate 0.05g, sodium lauryl sulfate 1.5g, sorbitol 21g, menthol 0.03g, peppermint oil 0.03g.
[0043] Experimental group 3: Tibetan medicine tooth...
Embodiment 3
[0050] Embodiment 3: experiment of treating periodontitis
[0051] Experimental groups 1, 2, 3, control groups 1, 2 and embodiment 2 are all the same.
[0052] The effect of the traditional Chinese medicine toothpaste prepared by experimental groups 1, 2, 3 and control group 1, 2 in treating periodontitis is measured by gingival index. The method is as follows: 300 volunteers are checked for oral cavity and scored. The scoring criteria are as follows: 1-no inflammation; 2-mild inflammation, slight changes in the color and texture of the gums; 3-moderate inflammation, the gums are bright, red, swollen, and hyperplastic; 4-severe inflammation, the gums are obviously red, hyperplastic, and spontaneous bleeding , weighted as mean value, use toothpaste of the present invention after 8 weeks, calculate weighted mean value again. Its therapeutic effect on periodontitis is shown in Table 2.
[0053] Table 2 Treatment effect of periodontitis in experimental group 1, 2, 3 and control ...
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