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Composition for dispelling effects of alcohol and protecting liver and application thereof

A technology of anti-alcoholic and liver-protecting and composition, which is applied in the direction of application, drug combination, and active ingredients of heterocyclic compounds, etc. It can solve the problems of inability to protect the liver and protect the liver, cure the symptoms but not the root cause, and can not be taken for a long time for conditioning. Aldehyde dehydrogenase activity, increase antioxidant active ingredients, reduce the effect of damage to the body

Pending Publication Date: 2021-03-30
SHANGHAI JIAODA ONLLY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] For excessive drinking or alcoholism, there are related chemical drugs and traditional Chinese medicines, but the chemical drugs themselves also need to be metabolized by the liver, and the metabolic process is also toxic to the liver. Therefore, western chemical drugs can only solve the adverse reactions of drunkenness immediately. It must not be used as a liver-protecting drug for long-term conditioning
The same traditional Chinese medicine for hangover is mostly based on the records of traditional Chinese medicine or ancient prescriptions, as well as modern pharmacology. Although it can temporarily relieve symptoms such as dizziness and nausea, many of them contain exciting active ingredients. , can only treat the symptoms but not the root cause
[0004] Although there are so-called TCM theories that treat both the symptoms and root causes of spleen-qi movement and transformation, liver-qi dredging and kidney-qi storage, there are few modern pharmacological experiments to prove it, and these compound Chinese medicines all contain traditional Chinese medicines that are not used for medicine and food. The taste of the medicine belongs to the therapeutic type, and cannot be taken for a long time for conditioning

Method used

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  • Composition for dispelling effects of alcohol and protecting liver and application thereof
  • Composition for dispelling effects of alcohol and protecting liver and application thereof
  • Composition for dispelling effects of alcohol and protecting liver and application thereof

Examples

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Effect test

preparation example Construction

[0021] The preparation method of the water extract (also known as crude drug extract) is not particularly limited in the present invention. The traditional Chinese medicines can be extracted separately and then mixed, or mixed and then jointly extracted, or any two or more kinds can be used. The traditional Chinese medicines are mixed and extracted; when they are extracted separately, the extraction method of each crude drug is the same. Taking Hovenia dulcis as an example, the following steps are included: put the crude drug Hovenia dulcis in the extraction tank, use 8 to 12 times the quality of drinking Slightly boil the water for the first extraction, and pass through a 60-100 mesh sieve; the filter residue is then subjected to 6-10 times the quality of drinking water for 1-2 times of slight boiling extraction, and pass through a 60-100 mesh sieve; discard the filter residue, combine the filtrate, Let it stand overnight, take the supernatant and concentrate it in vacuum to o...

Embodiment 1

[0038] 1, prepare crude drug as shown in Table 1;

[0039] Table 1 Crude drug composition

[0040] crude drug name Proportion of Crude Drug % Hovenia dulcis 47 Pueraria 25 hawthorn 8 nutmeg 8 ginseng 3 chrysanthemum 4 Galangal 4 Cinnamon 1 total 100

[0041] 2. Extraction of crude drug raw materials (mixed extraction)

[0042] Mix the crude drugs described in Table 1 and place them in the extraction tank, add up to 10 times the weight of the crude drugs in drinking water, heat to boiling, keep boiling slightly for 2 hours, filter through 80 mesh, and collect the filtrate; continue to add water to the filter residue 8 times, heat to boiling, Keep boiling slightly for 1.5 hours, filter at 80 mesh, discard the filter residue, combine the filtrate with the above filtrate, let it stand overnight, take the supernatant and concentrate it in vacuum until the solid content is about 20% (or the specific gravity is abo...

Embodiment 2

[0059] 1. Configure the crude drug according to the ratio shown in Table 3

[0060] Table 3 Crude drug preparation ratio

[0061] crude drug name Proportion of Crude Drug % Hovenia dulcis 40 Pueraria 19 hawthorn 10 nutmeg 11 ginseng 6 chrysanthemum 6 Galangal 6 Cinnamon 2 total 100

[0062] 2. Extraction of crude drug raw materials (mixed extraction)

[0063] Except that the crude drug preparation ratio is different, all the other operations are the same as in Example 1.

[0064] 3. Product preparation (capsules)

[0065] Table 4 product formula

[0066]

[0067]

[0068] 1) Formulation weighing

[0069] Take by weighing total crude drug extract, probiotic (Lactobacillus rhamnosus 0.8%, Bifidobacterium lactis 0.8%, Bifidobacterium longum 0.8%, Bifidobacterium breve 0.8%, Bacillus coagulans 0.8% by weighing total crude drug extract by formula shown in Table 4 ), taurine, vitamin B1, vitamin B2, vita...

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Abstract

The invention provides a composition for dispelling the effects of alcohol and protecting the liver and application thereof, and relates to the technical field of health care products. The compositioncomprises a water extract of medicinal and edible traditional Chinese medicines, probiotics, taurine, vitamin B and vitamin C. The composition is prepared from medicinal and edible crude drug raw materials specified by Ministry of Health and nutrition enhancer raw materials conforming to national standards of national food raw materials, has both treatment and health care effects, can be preparedinto health care products which have corresponding functions and can be eaten for a long time, and has the effects of dispelling the effects of alcohol immediately and protecting the liver after being taken for a long time.

Description

technical field [0001] The invention belongs to the technical field of health products, and in particular relates to a composition for relieving alcohol and protecting the liver and an application thereof. Background technique [0002] The World Health Organization (WHO) pointed out that alcoholism is still one of the public hazards in the world today. Excessive drinking and the diseases and problems caused by alcohol are also increasing, and most of the ethanol entering the body is metabolized by the liver, which has strong toxicity to the liver, such as lipid peroxidation on the surface of liver cell membranes and damage to liver cell membranes. Long-term drinking will also damage the microtubules and mitochondria in the liver cells, disturb the metabolism in the cells, produce cytotoxic metabolites, and cause swelling and necrosis of liver cells. [0003] For excessive drinking or alcoholism, there are related chemical drugs and traditional Chinese medicines, but the che...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P1/16A61P39/00A23L33/105A23L33/135A23L33/15A23L33/175A61K31/185A61K31/375A61K31/4415A61K31/51A61K31/525A61K35/744A61K35/745A61K35/747
CPCA23V2002/00A61K31/185A61K31/375A61K31/4415A61K31/51A61K31/525A61K35/744A61K35/745A61K35/747A61K36/185A61K36/258A61K36/287A61K36/488A61K36/54A61K36/72A61K36/734A61K36/9062A23L33/105A23L33/135A23L33/15A23L33/175A61P1/16A61P39/00A61K2300/00A23V2200/3204A23V2200/32A23V2250/0644A23V2250/206
Inventor 邵卫樑夏祎稚贾素中施云孙兆骐
Owner SHANGHAI JIAODA ONLLY CO LTD
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