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Near-infrared super-vision flexible artificial retina and manufacturing method thereof

A near-infrared and retinal technology, applied in artificial respiration, electrotherapy, treatment and other directions, can solve the problems of no major breakthrough in results, inability to achieve night vision function, and high difficulty in surgery, achieving low cost of material sources, easy implementation, and flexibility. good effect

Inactive Publication Date: 2021-04-13
NANJING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Whether it is a supraretinal prosthesis or a subretinal prosthesis, it basically recognizes the visible light band with a wavelength of 400-700nm, and cannot realize the night vision function. For the artificial retina with an infrared band greater than 800nm, it is often due to complex equipment and high heat production. There are many problems, such as difficulty in encapsulation and high difficulty in operation, and the results obtained have not made any major breakthroughs.

Method used

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  • Near-infrared super-vision flexible artificial retina and manufacturing method thereof
  • Near-infrared super-vision flexible artificial retina and manufacturing method thereof
  • Near-infrared super-vision flexible artificial retina and manufacturing method thereof

Examples

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Embodiment 1

[0032] Embodiment 1: see figure 1 , a flexible artificial retina for near-infrared super vision, which uses a flexible ferroelectric composite film with near-infrared photoelectric response to realize visual nerve stimulation and visual signal generation. The artificial retina includes photothermal materials for light absorption and iron for electrical signal output Electrical polymer materials and surfaces obtained by processing technology micro-nano-scale periodic lattice arrays. The artificial retina has a periodic array structure at the micro-nano scale, uses photothermal materials as light absorbers, and at the same time absorbs light to generate electrical signals "in situ", and uses the coupling of photothermal effect and pyroelectric response to realize artificial retina for near The problem of infrared light response, the photothermal material includes one or more of carbon materials, black scale, hexagonal boron nitride, transition metal sulfide, transition metal car...

Embodiment 2

[0033] Example 2: see figure 1 , a kind of manufacture method of near-infrared super vision flexible artificial retina, described method comprises the steps:

[0034] Step 1, cleaning of the "concave" array silicon template;

[0035] Step 2, configure the mixed solution of photothermal material and ferroelectric polymer material; dissolve the ferroelectric polymer powder in N,N-dimethylformamide under the action of magnetic stirring, and then mix the ferroelectric polymer and photothermal The N,N-dimethylformamide dispersion of the material is mixed, magnetically stirred and ultrasonically dispersed to obtain a uniformly distributed mixed solution. The ratio of photothermal material to ferroelectric polymer is between 1‰-10%, and their concentration in N,N-dimethylformamide is about 4wt%.

[0036] Step 3: using the silicon template solution pouring process, drop-coating the mixed solution of photothermal material and ferroelectric polymer on the "concave" array silicon templat...

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Abstract

The invention relates to a near-infrared super-vision flexible artificial retina. The artificial retina comprises a photo-thermal material for light absorption, a ferroelectric polymer material for electric signal output and a micro-nano-scale periodic dot matrix array obtained on the surface with a processing technology. The artificial retina has a micro-nano-scale periodic array structure, the photo-thermal material is used as a light absorber, meanwhile, an electric signal is generated in situ through light absorption, and the problem that the artificial retina responds to near-infrared light in a photo-thermal effect and pyroelectric response coupling mode is solved.

Description

technical field [0001] The invention relates to an artificial retina, in particular to a near-infrared super vision flexible artificial retina and a manufacturing method thereof, belonging to the technical field of implantable bioelectronic devices. Background technique [0002] Vision is one of the essential senses of human beings. Normally, the photosensitive wavelength band of the human visual nervous system is between 400-700nm, that is, the visible light band. For mammals, the photosensitive pigments in the retina fail to detect longer-wavelength light, such as near-infrared light, and bioelectronic devices can improve the photosensitive pigment's insufficient perception of infrared light. [0003] The prior art includes various forms of retinal implants. According to the location of the retinal implant device, it can be divided into two types, one is the retinal prosthesis, which generally consists of implanted devices (electrode arrays, batteries and wireless antenn...

Claims

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Application Information

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IPC IPC(8): A61F2/14A61N1/36A61L27/02A61L27/08A61L27/12A61L27/16A61L27/50
CPCA61F2/14A61N1/36046A61N1/36057A61N1/36103A61L27/02A61L27/08A61L27/12A61L27/16A61L27/50A61L2430/16C08L27/12
Inventor 沈群东沈小泉祁瑜聪
Owner NANJING UNIV
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