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Functional material digital design, preparation and evaluation automation platform

A functional material and platform technology, applied in the field of "island" and its overall platform, can solve problems such as method and step error, ambiguity, lack of digital normative, etc., to save time, improve accuracy, save cost and time-consuming Effect

Pending Publication Date: 2021-04-23
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide an automatic platform for digital design, preparation and evaluation of functional materials, which solves the problems of labor-intensive biochemical synthesis and preparation of high-performance materials, errors or ambiguities in methods and steps, and lack of Digitization normative issues, to realize the iterative innovation of digital "design-test-representation-learning-redesign" new functional materials

Method used

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  • Functional material digital design, preparation and evaluation automation platform
  • Functional material digital design, preparation and evaluation automation platform
  • Functional material digital design, preparation and evaluation automation platform

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Use the present invention for the preparation of MOFs protein

[0068] The first step: use the first manipulator 4 to place 1000 μl of ligand A, B and C solutions, five kinds of metal ions (Cu 2+ , Zn 2+ ,Co 2+ , Ni 2+ and Cd 2+ ) and 500 μl of the enzyme solution were transferred to a 96-well deep-well plate in storage area 14 of the raw material box as the mother solution in the raw material area.

[0069] Second step: utilize the second manipulator 7 to absorb and transfer five kinds of metal ions (Cu 2+ , Zn 2+ ,Co 2+ , Ni 2+ and Cd 2+ ) were placed in a 96-well plate in preparation zone 9, and repeated 3 times.

[0070] Step 3: Use the second manipulator 7 to suck up and transfer 50 μl of the enzyme solution to the same hole position as that in the preparation area of ​​the second step.

[0071] Step 4: Use the second manipulator 7 to absorb and transfer 50 μl of the solutions of ligands A, B, and C into the 96-well plate in the preparation area 9, and mi...

Embodiment 2

[0080] 1. The second manipulator 7 operates the pipette gun 36 to absorb 1-10ml of PbX in the substrate box 15 respectively 2 A saturated DMF solution of CsX and CsX (X=F, Cl or Br) is added to the precursor solution sample tank in the raw material box 14 .

[0081] 2. The second manipulator 7 operates the pipette gun 36 to absorb the long carbon chain organic acid (10-20 carbon content) and the long carbon chain small molecule amine (10-20 carbon content) in the substrate box 15, and the suction volume is 0.1 Between -2ml, add in the precursor solution sample groove in the raw material box 14.

[0082] 3. The second manipulator 7 operates the pipette gun 36 to repeatedly suck-release the precursor solution sample in the raw material box 15 to make it evenly mixed.

[0083] 4. The second manipulator 7 operates the pipette gun 36 to absorb solvents (including but not limited to toluene, chloroform, n-hexane, ethyl acetate, etc.) and add them to the 96-orifice plate in the vibr...

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Abstract

The invention belongs to the field of high-end equipment manufacturing, new materials, intelligent manufacturing, new-generation information technologies and biotechnologies and relates to a functional material digital design, preparation and evaluation automation platform. The platform comprises a first operation area, a second operation area, a third operation area, a first manipulator, a second manipulator and a third manipulator; the first manipulator transfers materials among the three operation areas; the second manipulator is used for extracting, transferring and mixing the materials in the second operation area; and the third manipulator is used for extracting, transferring and mixing the materials in the third operation area. The manipulators are adopted to replace an operator; material extraction, functional material formula screening, design, preparation and evaluation are carried out through person-human artificial intelligence-robot cooperation, and therefore, the labor intensity is reduced, time is saved, the experiment accuracy can be improved, and design, test, characterization, learning and redesign are completed; and digital manufacturing and iterative innovation of a novel functional material are realized.

Description

technical field [0001] The present invention relates to the fields of high-end equipment manufacturing, new materials, intelligent manufacturing, new generation information technology and biotechnology, and especially relates to a new type of high-performance energy, environmental protection, biomedicine and electronic information-related functional material structure design combined with robots and digital manufacturing , Preparation and evaluation of "islands" of different functional areas and their overall platforms. Background technique [0002] At present, the biochemical synthesis and preparation of high-performance materials in the fields of energy, environmental protection, biomedicine and electronic information are still labor-intensive, and some preparation methods and steps have errors or ambiguities. Therefore, it is necessary to develop new materials by "scientific intuition". The traditional model of "trial and error" has been transformed into a new model of "t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/01C07K1/00B65G47/90
CPCG01N21/01C07K1/00B65G47/902
Inventor 赵海涛喻学锋王本正康翼鸿李龙何睿
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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