Pharmaceutical composition for treating metabolism-related fatty liver disease as well as preparation method and application thereof
A composition and drug technology, applied in the field of medicine, can solve the problems of inability to improve liver histological changes and side effects, and achieve the effects of clear dosage, convenient administration, and small molecular weight
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Embodiment 1
[0033] A pharmaceutical composition for treating metabolic-related fatty liver disease is prepared from the following raw materials in parts by weight: 10 g of ginseng extract, 10 g of sorbitol, 10 g of microcrystalline cellulose, 10 g of magnesium stearate, and 10 g of transparent coating agent .
[0034] The dosage form of the finished preparation of the pharmaceutical composition is an acceptable dosage form prepared by conventional technical methods in pharmacy. The dosage form is preferably a tablet.
[0035] The preparation method of above-mentioned pharmaceutical composition comprises the steps:
[0036]Dissolve 50 g of red ginseng extract in an appropriate amount of deionized water to dissolve completely, then extract with chloroform for 3 times, combine the upper layer solutions to obtain a crude extract, and set aside. Put the crude extract into the pretreated macroporous resin chromatography column, after static adsorption for 20min, first elute with 2000mL of wat...
Embodiment 2
[0039] A pharmaceutical composition for treating metabolic-related fatty liver disease is prepared from the following raw materials in parts by weight: 10 g of ginseng extract, 100 g of sorbitol, 20 g of microcrystalline cellulose, 5 g of magnesium stearate, and 5 g of transparent coating agent .
[0040] The preparation method of the above-mentioned pharmaceutical composition is the same as in Example 1.
Embodiment 3
[0042] A pharmaceutical composition for treating metabolic-related fatty liver disease is prepared from the following raw materials in parts by weight: 10 g of ginseng extract, 100 g of sorbitol, 15 g of microcrystalline cellulose, 2 g of magnesium stearate, and 2 g of transparent coating agent .
[0043] The preparation method of the above-mentioned pharmaceutical composition is the same as in Example 1.
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