Protamine-PDRN complex, composition and application thereof in preparation of skincare products
A technology of PDRN and protamine, applied in the field of functional skin care products, can solve the problems of reducing curative effect, prone to allergies, cumbersome steps, etc., and achieve the effect of enhancing transdermal absorption effect, improving bioavailability, and clear active ingredients
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Embodiment 1
[0052] The construction of embodiment 1 protamine-PDRN complex
[0053] (1) First, mix 20mg / L protamine solution and 20mg / L PDRN solution according to the N / P ratio of 1.5:1, and stir at room temperature for 1h; (2) then let the mixture stand at room temperature for 1h; (3 ) Finally, the mixture was freeze-dried to obtain the protamine-PDRN complex.
Embodiment 2
[0054] The construction of embodiment 2 protamine-PDRN complex
[0055] (1) First, mix 20mg / L protamine solution and 20mg / L PDRN solution according to the N / P ratio of 2.0:1, and stir at room temperature for 1h; (2) Then let the mixture stand at room temperature for 1h; (3 ) Finally, the mixture was freeze-dried to obtain the protamine-PDRN complex.
Embodiment 3
[0056] Example 3 Construction of protamine-PDRN complex
[0057] (1) First, mix 20mg / L protamine solution and 20mg / L PDRN solution according to the N / P ratio of 2.5:1, and stir at room temperature for 1h; (2) Then let the mixture stand at room temperature for 1h; (3 ) Finally, the mixture was freeze-dried to obtain the protamine-PDRN complex.
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