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Antibacterial gel with inactivation effect on HPV (Human Papillomavirus)

A technology of HPV virus and gel, which is applied in the field of HPV virus drugs, can solve the problems of short local action time, skin aging, and inability to cover the range of medication, and achieve the effect of treating HPV virus infection

Inactive Publication Date: 2021-09-17
上海艾普愈生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment techniques for gynecological diseases caused by HPV virus include: injection intramuscular injection, oral medicine, surgery, etc. These methods have relatively large side effects on the human body; some medicines are mainly administered through the vagina, and the formulations of vaginal administration preparations are commonly used There are mainly suppositories, gels, effervescent tablets, vaginal tablets, lotions, capsules, films, etc., but these dosage forms have more or less defects that affect the function of drugs, such as suppositories, vaginal tablets, and effervescent tablets , capsules and films are used as solid preparations, which gradually release drugs to act on the vagina at body temperature. The contact area is small, and the drug effect is slow. Although the solid preparation has good local retention capacity, the drug range cannot cover the entire vagina; washing Although lotion is used as a medicine for cleaning the vagina, it can quickly clean and moisten the vagina and improve the speed of drug efficacy, but the local action time is too short and the lotion is easy to overflow the body, so the nursing and bactericidal effects are poor, and a large amount of lotion is often used Cleaning the reproductive tract will destroy the natural defense mechanism and ecological balance of the vagina
[0004] The Chinese patent with the existing application number 201410798607.9 discloses an anti-HPV virus gel dressing and a preparation method thereof. In the gel dressing, the main antibacterial / bacteriostatic agent is chlorhexidine, which is a chemical Synthetic drugs, long-term use is not good for the body, and the tea acid protein AP in the gel dressing needs to be combined with the positively charged virus coat protein, based on the blocking principle to prevent HPV virus infection, but only in the cervical epithelial mucosa. It can only be realized at the time of innovation, resulting in a small scope of application of the gel dressing; another example is the patent application number 201710033007.7 which discloses a pure Chinese medicine gel for the treatment of HPV-infected cervical cancer and its preparation method. Meridians, anti-inflammatory and sterilizing, dissipating stagnation and blood stasis can relieve most of the symptoms of patients with HPV virus. However, the vagina and other parts of patients infected with HPV virus also have skin tissue damage, itching, dryness and other problems due to the virus, and are prone to produce a large number of symptoms. Lipid peroxidation leads to symptoms such as skin aging, dullness, collapse, and relaxation. The existing patents cannot solve the above problems. Therefore, there are still room for improvement

Method used

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  • Antibacterial gel with inactivation effect on HPV (Human Papillomavirus)
  • Antibacterial gel with inactivation effect on HPV (Human Papillomavirus)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Horsetail Extract 3 parts

[0054] 115 parts of safflower extract

[0055] Romo extract 25 parts

[0056] 3 parts pectin

[0057] Carbomer 23 servings

[0058] 3 parts tea tree essential oil

[0059] 8 servings of probiotic ferments

[0060] 680 parts of purified water.

Embodiment 2

[0062] Horsetail extract 7 parts

[0063] 125 parts of safflower extract

[0064] Romo extract 75 parts

[0065] 7 parts pectin

[0066] Carbomer 27 servings

[0067] 7 servings of tea tree essential oil

[0068] 12 servings of probiotic ferments

[0069] 720 parts of purified water.

Embodiment 3

[0071] Horsetail Extract 5 parts

[0072] 120 parts of safflower extract

[0073] Romo extract 50 parts

[0074] 5 parts pectin

[0075] Carbomer 25 parts

[0076] Tea tree essential oil 5 parts

[0077] 10 servings of probiotic ferment

[0078] 700 parts of purified water.

[0079] In addition, in the present invention, the preparation method of the corresponding antibacterial gel is proposed for embodiments 1-3, specifically refer to the following:

[0080] Put the purified water into a vacuum emulsification tank and heat up to 85-95°C, add carbomer and stir for 40 minutes, then cool down to 35-40°C, then add horsetail extract, safflower extract, radish extract, fruit Put the gelatin and probiotic fermented product into the vacuum emulsification tank in turn, stir for 35 minutes, then add tea tree essential oil and stir for 30 minutes to obtain the finished HPV antibacterial gel.

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PUM

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Abstract

An antibacterial gel with an inactivation effect on HPV (Human Papillomavirus) relates to the technical field of HPV drugs; and the formula of the antibacterial gel comprises the following components: 3-7 parts of an equisetum extract, 115-125 parts of a safflower extract, 25-75 parts of a metaplexis japonica extract, 3-7 parts of pectin, 23-27 parts of carbomer, 3-7 parts of tea tree essential oil, 8-12 parts of a probiotic fermentation product, and 680-720 parts of purified water. The antibacterial gel disclosed by the invention is a gel product with medicinal and edible extracts, probiotic fermentation products and the like as active ingredients, can treat hpv infection, is non-irritant to vagina, is safe and free of side effects, carries antiviral, antibacterial, blood-activating, stasis-removing and pain-relieving ingredients, can rapidly permeate skin, protects mucous membrane cells from being damaged by viruses, also can improve the body immunity, has a good antiviral effect, and meanwhile, achieves the effects of diminishing inflammation, relieving pain, relieving itching and moistening the skin.

Description

technical field [0001] The invention relates to the technical field of HPV virus drugs, in particular to an antibacterial gel capable of inactivating HPV viruses. Background technique [0002] Human Papilloma Virus (HPV) is an epitheliophilic virus with high specificity. Known HPV can cause human benign tumors and warts, such as human common warts, condyloma acuminata, and papillomas that grow on the skin and mucous membranes near the reproductive organs. HPV is a DNA virus, which is a general term for a group of viruses. Clinically, it can be divided into many subtypes, and different subtypes can cause different diseases. According to the different types of HPV and the risk of tumor occurrence, HPV can be divided into low-risk types and high-risk types. Low-risk HPVs include HPV6, 11, 42, 43, 44, etc., which often cause benign lesions such as genital warts, including cervical low-grade intraepithelial lesions (CINI). High-risk HPV types include HPV16, 18, 31, 33, 35, 39,...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K9/06A61K47/32A61P15/02A61P17/04A61P17/18A61P29/00A61P31/20
CPCA61K36/11A61K36/286A61K36/27A61K36/61A61K9/06A61K9/0034A61K47/32A61K36/064A61P15/02A61P31/20A61P29/00A61P17/04A61P17/18A61K2300/00
Inventor 周水明
Owner 上海艾普愈生物医药科技有限公司
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