Fatty acid sustained-release composition for injection and preparation method and application thereof
A sustained-release composition and fatty acid technology, applied in the field of medicine, can solve problems affecting the stability of drug release of long-acting preparations, inability to adapt to clinical drug administration, unfavorable product quality control, etc., to improve burst release phenomenon, solid gel Dense structure, effect of promoting drug absorption
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[0025] Example 1
[0026] Ionophysterone 100 mg, dissolved in 700 mg of NMP, filtered through a 0.22 μm microporous filter film to obtain a drug solution, and then 200 mg of stearic acid, the magnetic force under sterile conditions was stirred for about 1 hour under sterile conditions, and was completely dissolved. Received clear transparent liquid, dispensing, sealed, and
Example Embodiment
[0027] Example 2
[0028] Odophil 100 mg, dissolved in an NMP of 700 mg, filtered through a 0.22 μm microporous filter film to obtain a drug solution, and then adding PLGA200 mg to sterile conditions, magnetic force under sterile conditions for about 1 hour, until completely dissolved, to be clarified Transparent liquid, dispensing, sealed,
Example Embodiment
[0029] Example 3
[0030] A hemolidone is 100 mg, dissolved in 800 mg of NMP, filtered through a 0.22 μm microporous filter film to obtain a drug solution, then in sterile conditions, 200 mg of peracate, magnetic force under sterile conditions for about 1 hour, completely dissolved Received clear transparent liquid, dispensing, sealed, and
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