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Polygonum multiflorum extract with functions of nourishing and strengthening eyebrows and preparation method

A technology for strengthening eyebrows and Polygonum multiflorum, which is applied in the directions of medical preparations containing active ingredients, hair care, drug combinations, etc., can solve the problems of users' health hazards, inconvenience to carry, and reduce convenience, so as to nourish and strengthen eyebrows and eyebrows. shedding, improving ease of use, reducing the effect of eyebrow shedding

Pending Publication Date: 2021-12-17
ZHEJIANG YIGE ENTERPRISE MANAGEMENT GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many defects in the use of the above-mentioned medicines: one is that the prescriptions of various medicines are complicated, and they need to be prescribed by a professional doctor, so daily personal maintenance cannot be realized; Poor, thereby reducing the user's compliance, and there will be certain side effects after taking the drug, which will cause hidden dangers to the user's health; the third is that the user needs to carry the above-mentioned drugs when going out, thereby reducing its convenience.
[0004] Therefore, the existing methods of using Radix Polygoni Multiflori to treat patients with sparse eyebrows have the problems of difficulty in daily use, poor compliance and inconvenient portability.

Method used

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  • Polygonum multiflorum extract with functions of nourishing and strengthening eyebrows and preparation method

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0022] Based on the preparation method of a Polygonum multiflorum extract with nourishing and strong eyebrows, it comprises the following steps:

[0023] ①Crush and sieve Polygonum multiflorum, add 10 times the amount of 70% ethanol, then ultrasonically extract 3 times and combine the extracts to obtain product A;

[0024] ② Concentrate and dry product A under reduced pressure in turn to obtain product B;

[0025] ③ Put product B into an enzyme reactor and add 4 times of water to dilute, then add compound enzyme and stir at 6.0pH and 60°C to obtain product C;

[0026] ④ Enzymolysis reaction of product C for 24 hours, and then passivation treatment at 80°C for 30 minutes to obtain product D;

[0027] ⑤ Inoculate Lactobacillus brevis into MRS medium, then place it in an anaerobic incubator and culture it at 37°C for 24 hours, and after microscopic inspection without any bacteria, carry out secondary expansion culture under the same conditions to obtain product e1. Centrifuge t...

experiment example 1

[0035] Experimental Example 1: Set up a sample group and a blank control group. In the sample group, the final product prepared in this example was dissolved in deionized water, and an appropriate amount of preservative was added to prepare an aqueous solution with a mass fraction of 1%, which was applied twice a day on For eyebrows, use for six weeks. The blank control group was not treated.

[0036] Then use the eyebrow density measurement method to detect the comparison ratio of the two groups, specifically: use a hair follicle analyzer, place the lens flat on the eyebrow peak, make the center point of the lens overlap with the midpoint of the eyebrow width at the eyebrow peak, and repeatedly shoot the left and right eyebrows Three times, a total of six pictures. The magnification is 75 times, each eyebrow is marked on the picture, and the 1cm of the eyebrow peak is automatically calculated by the system 2 The number of eyebrows contained is the eyebrow density, and the a...

experiment example 2

[0040] Experimental Example 2: Taking resveratrol as a reference substance, the Radix Polygoni Multiflori extract prepared by the present invention was measured by first-order derivative spectroscopy at a wavelength of 330nm. %above.

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Abstract

The invention discloses a polygonum multiflorum extract with the functions of nourishing and strengthening eyebrows. The content of total stilbene compounds in the extract is greater than or equal to 85%. Meanwhile, the invention discloses a preparation method of the extract. The method comprises the following steps of crushing and sieving polygonum multiflorum, then adding ethanol to obtain an extracting solution, then sequentially carrying out vacuum concentration and drying on the extracting solution, and then putting the extracting solution into an enzyme reactor to carry out enzymolysis reaction and passivating treatment with compound enzyme; inoculating a treated material with lactobacillus brevis, and fermenting to obtain a solid component; extracting and drying the solid component under reduced pressure, dissolving with water, performing standing and filtering, and adsorbing a filtrate by using AB-8 macroporous resin; and eluting the AB-8 macroporous resin, and carrying out vacuum concentration and drying on an eluent to obtain the finished product. The total stilbene compounds in the polygonum multiflorum can be extracted, so that the total stilbene compounds can be directly added into cosmetics and daily maintenance of a user is realized; and the polygonum multiflorum extract has the characteristics of good compliance and convenience in carrying.

Description

technical field [0001] The invention relates to an extraction method of Polygonum multiflorum, in particular to an extract of Polygonum multiflorum with the function of nourishing and strengthening eyebrows and a preparation method thereof. Background technique [0002] Sparse eyebrows means that the eyebrows cannot completely cover the skin of the eyebrow growth area, usually accompanied by dry eyebrows, easy to break, easy to fall off, itching and other symptoms. Traditional Chinese medicine believes that the etiology and pathogenesis of thin eyebrows include deficiency of qi and blood, blood stasis blocking collaterals, blood heat generating wind, blood dryness generating wind, insufficient liver blood, excessive fire in the liver meridian, deficiency of kidney essence, and insufficient lung qi, etc. Deficiency, wind, heat, and blood stasis caused by the imbalance of qi, blood, viscera, meridians and collaterals can all cause eyebrows to lose their nourishment and fall of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q7/00A61P17/00
CPCA61K8/9789A61Q7/00A61P17/00A61K2800/805A61K2800/82
Inventor 张大勇毕永贤周浩淼胡雪情唐萌陆雨清
Owner ZHEJIANG YIGE ENTERPRISE MANAGEMENT GRP CO LTD
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