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Pharmaceutical composition for treating atrophic gastritis and preparation method

A technology for atrophic gastritis and a composition is applied in the field of pharmaceutical compositions and preparations for the treatment of atrophic gastritis, and can solve the problems of atrophic gastritis and the like

Inactive Publication Date: 2021-12-17
刘兰英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a pharmaceutical composition for treating atrophic gastritis. This formula has the functions of nourishing spleen and stomach qi and yin, treating deficiency of spleen and kidney yang, stagnation of dampness and heat in the stomach, and spleen soil counteracting liver wood, and solving the problem of atrophic gastritis. Gastritis is a problem that cannot be cured for a long time
[0004] The purpose of the present invention is to provide a pharmaceutical composition for treating atrophic gastritis. This formula has the functions of nourishing spleen and stomach qi and yin, treating deficiency of spleen and kidney yang, stagnation of dampness and heat in the stomach, and spleen soil counteracting liver wood, and solving the problem of atrophic gastritis. Gastritis is a problem that cannot be cured for a long time
[0005] Another object of the present invention is to provide a method for preparing a pharmaceutical composition for treating atrophic gastritis. The prepared honeyed pill has better nourishing spleen and stomach qi and yin, and can treat deficiency of spleen and kidney yang, accumulation of dampness and heat in the stomach and spleen soil. The effect of rebelling against liver wood has solved the problem of atrophic gastritis that cannot be cured for a long time

Method used

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preparation example Construction

[0077] On the other hand, the embodiment of the present application provides a preparation method of a pharmaceutical composition for treating atrophic gastritis, which includes the following steps: after pulverizing all raw materials, according to the mass ratio of raw materials and ethanol of 1:10-12, through 78-80wt% ethanol alcohol extraction for 2-4 hours to prepare the ethanol extract, and the solid obtained after filtering the above ethanol extract is vacuum-dried to obtain the first medicinal powder, the drying temperature is 70-80°C, and the vacuum degree is 1.05-1.3Mpa; The liquid obtained after filtering the above-mentioned ethanol extract is subjected to high-speed centrifugation, precipitated until solid-liquid separation, extracts the sinking organic matter and concentrates the organic matter into a slurry by vacuum distillation, and prepares the second medicinal powder after drying; Wuhuo will finely sieve The final honey is boiled and then simmered for 2-6 hours...

Embodiment 1

[0108] The embodiment of the present application provides a pharmaceutical composition for treating atrophic gastritis. Accurately weigh 9g of Radix Polygonatum, 9g of Polygonatum Polygonatum, 9g of Scutellariae Radix, 9g of Coptidis Rhizoma, 9g of Phellodendron Phellodendri, 10g of Codonopsis Codonopsis, 10g of Atractylodes Rhizome, 10g of Poria cocos, 6g of licorice, and 9g of Qinpi , Galangal 6g, Evodia 10g, nutmeg 5g, Toosendan 15g and Yuanhu 10g. The above-mentioned raw materials are processed into small honeyed pills after powdering, so as to make a medicine for treating atrophic gastritis. The preparation method of the above-mentioned honeyed pills is any conventional method, and will not be described in detail here. Optionally, the conventional specifications for making small honeyed pills can be set through the pill making machine, for example, the weight of each pill is 0.15-0.25g.

Embodiment 2

[0110] The difference between this example and the raw materials in Example 1 is that the above-mentioned pharmaceutical composition for treating atrophic gastritis also includes Pinellia 10g, Galangal 6g, Radix Paeoniae Alba 9g, Chinese yam 15g, Jiao Sanxian 30g, Angelica 10g, Danpi 10g, white cardamom 10g, cuttlefish bone 15g, zedoary 10g and Magnolia officinalis 10g.

[0111] Accurately weigh 9g of Radix Ginseng, 9g of Polygonatum Polygonatum, 9g of Scutellaria, 9g of Coptidis, 9g of Phellodendron, 10g of Codonopsis, 10g of Atractylodes macrocephala, 10g of Poria cocos, 6g of licorice, 9g of Qinpi, 6g of ginger, 10g of evodia, 5g of nutmeg, 15g of toosendan , Yuanhu 10g, raw white peony root 9g, yam 15g, Jiao Sanxian 30g, angelica 10g, paeonol 10g, white cardamom 10g, cuttlefish bone 15g, curcuma 10g and Magnolia officinalis 10g, make honeyed pills after powdering, the preparation of the above honeyed pills The method is any conventional means, and will not be described in ...

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PUM

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Abstract

The invention provides a pharmaceutical composition for treating atrophic gastritis and a preparation method, and relates to the field of atrophic gastritis. The pharmaceutical composition for treating the atrophic gastritis is prepared from the following components in parts by weight of 9 parts of radix adenophorae, 9 parts of radix polygonati officinalis, 9 parts of radix scutellariae, 9 parts of rhizoma coptidis, 9 parts of cortex phellodendri, 10 parts of radix codonopsis, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of poria cocos, 6 parts of radix glycyrrhizae, 9 parts of cortex fraxini, 6 parts of galangal, 10 parts of fructus evodiae, 5 parts of semen myristicae, 15 parts of fructus toosendan and 10 parts of rhizoma corydalis. In addition, the invention discloses a preparation method of the pharmaceutical composition. The method comprises the following steps of pulverizing all the raw materials, carrying out alcohol extraction for 2-4 hours by using 78-80wt% of ethanol according to a mass ratio of the raw materials to the ethanol of 1: (10-12) to obtain an ethanol extract, filtering the ethanol extract, and carrying out vacuum drying on obtained solid medicine residues. The pharmaceutical composition has the effects of tonifying qi and yin in the spleen and stomach, and treating spleen-kidney yang deficiency, damp-heat accumulation in the stomach and insulting of the liver by the spleen.

Description

technical field [0001] The invention relates to the field of atrophic gastritis, in particular to a pharmaceutical composition for treating atrophic gastritis and a preparation method. Background technique [0002] Chronic atrophic gastritis, referred to as (CAG), is a common disease, and the World Health Organization lists it as a precancerous state of the stomach, especially those with intestinal metaplasia or atypical hyperplasia, which are more likely to become cancerous. Its onset is slow, the condition is lingering, protracted and difficult to heal, and the treatment is difficult. There is no name of atrophic gastritis in the medical literature of the motherland. Spleen fullness and pain in the epigastrium are common, or full spleen without pain, and a small number of patients have no obvious symptoms. Therefore, the third Spleen and Stomach Academic Conference of the National Association of Traditional Chinese Medicine believes that chronic atrophic gastritis can be a...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P1/04A61K36/9066
CPCA61K36/342A61K36/34A61K36/23A61K36/8969A61K36/539A61K36/718A61K36/756A61K36/344A61K36/284A61K36/076A61K36/484A61K36/63A61K36/9062A61K36/754A61K36/185A61K36/58A61K36/66A61K36/8888A61K36/71A61K36/65A61K36/8945A61K36/8998A61K36/734A61K36/00A61K36/232A61K36/9064A61K35/618A61K36/9066A61K36/575A61K9/2068A61P1/04A61K2236/333A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 刘兰英
Owner 刘兰英
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