The present invention discloses a method for preparing a postoperative wound intelligent healing patch based on
nanomaterials, comprising the following steps: S1, preparing a
temperature response layer, using PNIPAM and surface-modified
zinc oxide nanoparticles for compounding; S2, preparing a pH response layer, compounding
chitosan with surface-modified
titanium dioxide nanoparticles; S3, preparing a
humidity response layer, using PEGDA and
silver nanoparticle composite materials to optimize the release of silver ions; S4, assembling each layer layer by layer through
electrospinning technology or lamination technology, and combining meta-learning and transfer learning to control process parameters to complete the overall structure preparation of the patch; S5, embedding temperature, pH and
humidity sensors to construct a sensor
data set; S6, dynamically adjusting the
drug release rate and material
phase change behavior to achieve accurate response; S7, after the patch is prepared, combining Bayesian and multi-objective evolutionary algorithms to optimize sterilization parameters. The present invention combines
nanomaterials with
intelligent algorithms to prepare intelligent healing patches and achieve real-time environmental response.