Automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics

Abstract

The invention belongs to the field of medical image processing and application, and relates to a medical image follow-up processing analysis technology, in particular to an automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics, in particular to a three-dimensional hemodynamics automatic calculation process. A calculation program of the system comprises a model preprocessing module, a tracer particle module, a track statistics module, a skeleton extraction module, a griding sub-module and a fluid solving module. A main program of the calculation program is based on a python language, and a complex function module is packaged into a dynamic library based on C++ to be called by the main program. According to the process, a user only needs to provide a blood vessel stl model and designate the inlet and outlet surfaces of blood flow in the model and corresponding boundary conditions, and then the blood flow field quantity result can be automatically output. Blood flow simulation calculation can be completed through interaction with clinicians as little as possible, the aneurysm rupture risks are judged to be an extremely high risk group, a high risk group, a medium risk group and a low risk group, a physical simulation technology can be conveniently used for assisting an operation scheme, and clinical application is facilitated.

Description

technical field [0001] The invention belongs to the field of medical image processing and application, and relates to medical image follow-up processing analysis technology, in particular to an automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics, especially a three-dimensional hemodynamics automatic calculation process , its calculation program includes model preprocessing module, tracer particle module, track statistics module, skeleton extraction module, grid sub-module and fluid solution module to design a program that can automatically execute the output of blood flow field results. It can complete the simulation calculation of blood flow, judge the risk of aneurysm rupture, and facilitate the use of physical simulation technology to assist surgical planning, which is helpful for clinical application. Background technique [0002] Studies have reported that the exact cause of intracranial aneurysms is not very clear, and studies have s...

AI Technical Summary

Problems solved by technology

[0005] In clinical practice, for simple intracranial aneurysms that have been ruptured, the corresponding surgical treatment can be directly selected. Clinical diagnosis and treatment can provide great help, helping doctors to better understand the hemodynamic characteristics of the aneurysm, helping to judge the maximum stress position and possible rupture position of the aneurysm wall, the doctor refers to the calculation results, combined with the anatomy of nearby blood vessels structure, you can choose the appropriate surgical method (interventional embolization, craniotomy aneurysm clipping); for example, if the numerical simulation predicts that the Von Mises stress at the bottom of the saccular aneurysm increases significantly, the choice of interventional embolization may increase the chance of spring embolism puncturing the artery The risk of intracranial hemorrhage caused by the aneurysm wall, it is best to choose craniotomy and clipping in this case; of course, the best surgical method to choose based on the results of numerical simulation research has not yet reached a conclusion, and further research on a large number of intracranial aneurysms is needed. Numerical simulation research, and research on the relationship between the results of numerical simulation research and the choice of surgical methods and prognosis

[0006] Numerical calculation of intracranial aneurysm is an interdisciplinary research. The calculation of blood flow is based on CFD program, and the mechanical analysis of blood vessel wall is based on CAE program. The whole analysis process involves fluid mechanics, mathematics, computer software, computer simulation, finite element method, material science, Topology, medicine, etc., the process of using commercial software analysis is also more specialized in mechanics. At present, there are few people who have fully mastered the above research methods, and the methods have not been widely promoted in clinical work.

Images