Automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics

A flow dynamics and cerebral aneurysm technology, applied in the field of automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics, can solve the problems of adding spring plugs and increasing stress

Pending Publication Date: 2022-01-04
AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In clinical practice, for simple intracranial aneurysms that have been ruptured, the corresponding surgical treatment can be directly selected. Clinical diagnosis and treatment can provide great help, helping doctors to better understand the hemodynamic characteristics of the aneurysm, helping to judge the maximum stress position and possible rupture position of the aneurysm wall, the doctor refers to the calculation results, combined with the anatomy of nearby blood vessels structure, you can choose the appropriate surgical method (interventional embolization, craniotomy aneurysm clipping); for example, if the numerical simulation predicts that the Von Mises stress at the bottom of the saccular aneurysm increases significantly, the choice of interventional embolization may increase the chance of spring embolism puncturing the artery The risk of intracranial hemorrhage caused by the aneurysm wall, it is best to choose craniotomy and clipping in this case; of course, t

Method used

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  • Automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics
  • Automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics
  • Automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics

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Experimental program
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Effect test

Embodiment 1

[0027] The particle discrete element method (DEM) is used to calculate the movement of particles under the action of external force, the process is as follows figure 1 shown), the force between the particles and the particle-surface is equivalent to a spring-damper model, and the spring and damper are applied in the normal direction n and the tangential direction t respectively; for two contact particles i and j, the radii are Ri and Rj, the governing equation of particle i velocity angular velocity is:

[0028]

[0029]

[0030] Among them, mi and Ii respectively represent the mass and moment of inertia of particle i, and Nc is the number of neighbor particles in contact with particle i. The program uses the simplified Hertz–Mindlin–Deresiewicz contact model to calculate the contact force between particles:

[0031]

[0032]

[0033] where k and γ represent stiffness and damping coefficient; Represents the relative velocity between particles; μ represents the f...

Embodiment 2

[0058] Because the vortex area is often the area of ​​clinical concern, it is usually the key position that affects the grid quality. Traditionally, it is difficult to properly divide all areas when the overall grid division of the vascular model is performed. It often requires repeated compromises and attempts to obtain A relatively complete overall grid requires a lot of human-computer interaction; the program in the present invention divides the stl model of the blood vessel according to the vortex area, and each subset after segmentation is divided into independent grids, and there is no difference between different blood vessel units. Grid consistency is required. Therefore, the topological shape and blood flow characteristics of each grid unit are relatively single, and a fluid grid that meets its flow characteristics can be generated for each blood vessel subset, which is the key to the automation of the entire simulation process;

[0059] After the grid subset is genera...

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Abstract

The invention belongs to the field of medical image processing and application, and relates to a medical image follow-up processing analysis technology, in particular to an automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics, in particular to a three-dimensional hemodynamics automatic calculation process. A calculation program of the system comprises a model preprocessing module, a tracer particle module, a track statistics module, a skeleton extraction module, a griding sub-module and a fluid solving module. A main program of the calculation program is based on a python language, and a complex function module is packaged into a dynamic library based on C++ to be called by the main program. According to the process, a user only needs to provide a blood vessel stl model and designate the inlet and outlet surfaces of blood flow in the model and corresponding boundary conditions, and then the blood flow field quantity result can be automatically output. Blood flow simulation calculation can be completed through interaction with clinicians as little as possible, the aneurysm rupture risks are judged to be an extremely high risk group, a high risk group, a medium risk group and a low risk group, a physical simulation technology can be conveniently used for assisting an operation scheme, and clinical application is facilitated.

Description

technical field [0001] The invention belongs to the field of medical image processing and application, and relates to medical image follow-up processing analysis technology, in particular to an automatic cerebral aneurysm rupture risk analysis system based on cerebral hemodynamics, especially a three-dimensional hemodynamics automatic calculation process , its calculation program includes model preprocessing module, tracer particle module, track statistics module, skeleton extraction module, grid sub-module and fluid solution module to design a program that can automatically execute the output of blood flow field results. It can complete the simulation calculation of blood flow, judge the risk of aneurysm rupture, and facilitate the use of physical simulation technology to assist surgical planning, which is helpful for clinical application. Background technique [0002] Studies have reported that the exact cause of intracranial aneurysms is not very clear, and studies have s...

Claims

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Application Information

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IPC IPC(8): G06F30/28G16H50/30A61B5/00A61B5/02A61B5/026
CPCG06F30/28G16H50/30A61B5/02007A61B5/02014A61B5/026A61B5/7235A61B5/7275A61B5/7271
Inventor 朱凤平毛颖
Owner AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
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