Novel fluorescence detection reagent and technology for quantitatively detecting in-vivo and in-vitro CO
A fluorescence detection and reagent technology, applied in the field of analysis and detection, can solve the problems of limited large-scale use, weak tissue penetration ability, short emission wavelength, etc., and achieve strong practical application value, low cytotoxicity, and high specificity
Pending Publication Date: 2022-03-01
HUNAN TARGETING DETECTION TECH CO LTD
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Abstract
The invention discloses a novel fluorescence detection reagent and a technology for quantitatively detecting in-vivo and in-vitro CO, and relates to a near-infrared fluorescence probe, the chemical structural formula of the near-infrared fluorescence probe is shown in the specification, and the fluorescence detection reagent can realize high-sensitivity and high-specificity detection of CO in environment, cells or organisms. Meanwhile, the probe used in the invention is a near-infrared probe, has good biological tissue permeability, low cytotoxicity and excellent water solubility, can avoid interference from biomacromolecule background fluorescence, can also be applied to detection of endogenous CO in living cells so as to realize in-vivo and in-vitro quantitative analysis and detection of CO, and has wide application.
Application Domain
Organic chemistryFluorescence/phosphorescence +1
Technology Topic
Biological tissueBackground fluorescence +14
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