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Liquid dressing for repairing skin wound as well as preparation method and application of liquid dressing

A liquid dressing and skin wound technology, applied in medical science, bandages, absorbent pads, etc., can solve the problems of poor antibacterial and anti-infection effects, avoid secondary infection and allergic reactions, enhance soothing effect, and increase the ability of Effect

Active Publication Date: 2022-03-18
湖南银华棠医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the prior art, there is no report on the use of nano-scale hydroxyapatite ultrafine powder in a specific particle size range for anti-bacterial infection and promotion of wound repair.
[0006] In view of the generally poor effects of antibacterial, anti-infection, and wound healing promotion of medical dressings for wound repair used clinically and in the field of medical cosmetology, the inventor first proposed a device for skin wound repair. Modified Liquid Dressing

Method used

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  • Liquid dressing for repairing skin wound as well as preparation method and application of liquid dressing
  • Liquid dressing for repairing skin wound as well as preparation method and application of liquid dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] A liquid dressing for repairing skin wounds. In terms of weight percentage, the liquid dressing is made of the following raw materials: 0.15 grams of D-(+)-trehalose dihydrate, 0.15 grams of zinc hyaluronate, and 2 grams of butanediol , 3 grams of glycerin, 1 gram of carbomer, 1 gram of xanthan gum, 0.04 gram of disodium EDTA, 0.15 gram of allantoin, 1 gram of BP20, 0.1 gram of triethanolamine and purified water to 100 grams, among which the low molecular weight ≤ 10kDa The molecular weight zinc hyaluronate accounts for more than 40% of the total weight of the zinc hyaluronate.

[0050] The medical dressing prepared with the above-mentioned liquid dressing for skin wound repair is a facial mask, an eye mask or an applicator, and the preparation method comprises the following steps:

[0051] Step (1): Weigh the carbomer and purified water respectively according to the weight percentage, pump the purified water into the emulsification pot, turn on the homogenization speed...

Embodiment 2

[0056] A liquid dressing for repairing skin wounds. In terms of weight percentage, the liquid dressing is made of the following raw materials: 0.15 grams of D-(+)-trehalose dihydrate, 0.15 grams of zinc hyaluronate, and 2 grams of butanediol , 3 grams of glycerin, 5 grams of carbomer, 0.1 gram of allantoin, 0.3 gram of triethanolamine and purified water to 100 grams, wherein the low molecular weight zinc hyaluronate with a molecular weight≤10kDa accounts for 40% of the total weight of the zinc hyaluronate %above.

[0057] The medical dressing prepared from the liquid dressing for skin wound repair is a gel for external use on the skin, and the preparation method comprises the following steps:

[0058] Step (1): Weigh the carbomer and purified water respectively according to the weight percentage, pump the purified water into the emulsification pot, turn on the homogenization speed at 20-30Hz, then add the carbomer into the emulsification pot to obtain the mixture 1, statically...

Embodiment 3

[0062] A liquid dressing for repairing skin wounds. In terms of weight percentage, the liquid dressing is made of the following raw materials: 0.15 grams of D-(+)-trehalose dihydrate, 0.15 grams of zinc hyaluronate, and 2 grams of butanediol , 3 grams of glycerin, 0.03 gram of disodium EDTA and purified water to 100 grams, wherein the low molecular weight zinc hyaluronate with molecular weight≤10kDa accounts for more than 40% of the total weight of the zinc hyaluronate.

[0063] The medical dressing prepared with the above-mentioned liquid dressing for skin wound repair is a skin repair liquid, and the preparation method comprises the following steps:

[0064] Step (1): Weigh purified water and disodium EDTA by weight percentage, pump the purified water into an emulsification pot, add disodium EDTA, stir at 180r / min for 10min at room temperature to obtain a mixture 1, and let it stand for later use;

[0065] Step (2): Weigh glycerin, butanediol, zinc hyaluronate, and D-(+)-tre...

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Abstract

The invention belongs to the field of medical dressings, and particularly relates to a liquid dressing for skin wound repair and a preparation method and application thereof. The liquid dressing for skin wound repair is prepared from the following raw materials in percentage by weight: 0.05 to 0.2 percent of D-(+)-trehalose dihydrate, 0.05 to 0.2 percent of hyaluronate, 1 to 5 percent of butanediol, 1 to 5 percent of glycerol and the balance of purified water. Experimental results show that the liquid dressing prepared by the technical scheme of the invention is safe and non-irritant, can protect skin wounds from being invaded by external pollutants and bacteria, and has the effects of moisturizing and repairing wound skin at the same time.

Description

technical field [0001] The invention belongs to the field of medical dressings, and in particular relates to a liquid dressing for repairing skin wounds, a preparation method and application thereof. Background technique [0002] With the development of society, people's pursuit of beauty is getting higher and higher, so medical cosmetology has gradually become a hot spot for public consumption. At present, the research on laser, fruit acid peeling, microdermabrasion, hydrolight, and microneedling is being deepened and widely used. The damage of the skin affects the barrier function of the skin, thus prone to skin symptoms such as skin erythema, edema, scars, and pigmentation. Therefore, how to effectively repair wounds after laser, fruit acid peeling, microdermabrasion, hydrotherapy, and microneedling has become an important research hotspot. [0003] The existing medical dressings for wound repair have a relatively single formula, most of which are a single sodium hyalur...

Claims

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Application Information

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IPC IPC(8): A61L15/18A61L15/20A61L15/24A61L15/28A61L15/44A61L15/46
CPCA61L15/20A61L15/28A61L15/24A61L15/18A61L15/44A61L15/46A61L2300/112A61L2300/404A61L2300/41A61L2300/412
Inventor 陈冲
Owner 湖南银华棠医药科技有限公司
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