Pharmaceutical composition for treating ulcerative colitis and preparation method thereof

A technology for ulcerative colitis and a composition, applied in the field of medicine, can solve the problems of long treatment period, large toxic and side effects, unsatisfactory curative effect, etc., and achieve the effects of relieving abdominal pain symptoms, promoting healing, and relieving symptoms of blood in the stool

Pending Publication Date: 2022-07-08
ZHANGZHOU SHUIXIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment drugs for ulcerative colitis include aminosalicylic acid preparations, glucocorticoids, immunosuppressants, biological agents, etc., which can alleviate the pain of patients to a certain extent, but the treatment cycle is long, the side effects are large, the curative effect is not ideal, and the disease recurs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A pharmaceutical composition for treating ulcerative colitis, comprising Codonopsis pilosula, Astragalus, Atractylodes Rhizoma, Zhigancao, Coix seed, ebony, lotus seed flesh, Cortex Phellodendri, tangerine peel, Bupleurum chinensis, Coptis chinensis, Angelica sinensis, bran fried Atractylodes, Qinpi, Baishao, Wood Fragrance, Sandalwood, Agrimony, Sorrel, Amomum, Fried Burnet and Dendrobium officinale.

[0028] Further, the parts by weight of the medicinal materials in the pharmaceutical composition are: 25 parts of Codonopsis Radix, 20 parts of Astragalus, 10 parts of Atractylodes Rhizoma, 20 parts of Zhigancao, 8 parts of Coix Seed, 13 parts of ebony, 6 parts of lotus seeds, 6 parts of Treats 8 parts, 6 parts of tangerine peel, 25 parts of Bupleurum, 6 parts of Coptis chinensis, 3 parts of Angelica, 8 parts of bran fried Atractylodes, 13 parts of Qin Pi, 20 parts of White Peony, 8 parts of Muxiang, 6 parts of Sandalwood, 10 parts of Agrimony, 6 parts of Paijiangcao, 8 ...

Embodiment 2

[0041] A pharmaceutical composition for treating ulcerative colitis, comprising Codonopsis pilosula, Astragalus, Atractylodes Rhizoma, Zhigancao, Coix seed, ebony, lotus seed flesh, Cortex Phellodendri, tangerine peel, Bupleurum chinensis, Coptis chinensis, Angelica sinensis, bran fried Atractylodes, Qinpi, Baishao, Wood Fragrance, Sandalwood, Agrimony, Sorrel, Amomum, Fried Burnet and Dendrobium officinale.

[0042] Further, the parts by weight of the medicinal materials in the pharmaceutical composition are: 26 parts of Codonopsis Radix, 22 parts of Astragalus, 12 parts of Atractylodes Rhizoma, 23 parts of Zhigancao, 9 parts of Coix Seed, 14 parts of ebony, 7 parts of lotus seed flesh, Phellodendron chinensis 10 parts, 8 parts of tangerine peel, 28 parts of Bupleurum, 7 parts of Coptis chinensis, 5 parts of Angelica root, 11 parts of bran fried Atractylodes, 16 parts of Qin Pi, 22 parts of Baishao, 9 parts of Muxiang, 8 parts of Sandalwood, 13 parts of Agrimony, 7 parts of P...

Embodiment 3

[0055] A pharmaceutical composition for treating ulcerative colitis, comprising Codonopsis pilosula, Astragalus, Atractylodes Rhizoma, Zhigancao, Coix seed, ebony, lotus seed flesh, Cortex Phellodendri, tangerine peel, Bupleurum chinensis, Coptis chinensis, Angelica sinensis, bran fried Atractylodes, Qinpi, Baishao, Wood Fragrance, Sandalwood, Agrimony, Sorrel, Amomum, Fried Burnet and Dendrobium officinale.

[0056]Further, the parts by weight of the medicinal materials in the pharmaceutical composition are: 30 parts of Codonopsis Radix, 24 parts of Astragalus, 15 parts of Atractylodes Rhizoma, 24 parts of Zhigancao, 12 parts of Coix Seed, 18 parts of ebony, 9 parts of lotus seeds, 9 parts of Treats 12 parts, 9 parts of tangerine peel, 30 parts of Bupleurum, 9 parts of Coptis chinensis, 6 parts of Angelica sinensis, 12 parts of bran fried Atractylodes, 18 parts of Qin Pi, 24 parts of Paeonia lactiflora, 12 parts of Muxiang, 9 parts of Sandalwood, 15 parts of Agrimony, 9 parts...

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PUM

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Abstract

The invention provides a pharmaceutical composition for treating ulcerative colitis. The pharmaceutical composition is prepared from codonopsis pilosula, astragalus membranaceus, rhizoma atractylodis macrocephalae, honey-fried licorice roots, coix seeds, smoked plums, lotus seed pulp, cortex phellodendri, pericarpium citri reticulatae, radix bupleuri, coptis chinensis, angelica sinensis, bran-fried rhizoma atractylodis, cortex fraxini, radix paeoniae alba, radix aucklandiae, sandalwood, hairyvein agrimony, herba patriniae, fructus amomi, fried sanguisorba officinalis and dendrobium officinale. Astragalus mongholicus can tonify qi and spleen, strengthen intestines and stop diarrhea, and promote ulcer healing; dendrobium officinale has the effects of resisting inflammation, resisting bacteria and regulating a cardiovascular system; according to the traditional Chinese medicine composition disclosed by the invention, the healing of colon tissues is promoted through the ways of combined use of the medicines, combined application of astringency, simultaneous regulation of qi and blood, qi replenishing and spleen strengthening, inflammation diminishing, cell apoptosis inhibiting, inner wall cell growth promoting, cell factor regulation and the like, so that the hemafecia symptom and stomachache symptom are relieved, liver qi is treated and discharged, the spleen and stomach are regulated, and the regulating ability of the body is fully exerted; the neuroendocrine system is regulated, so that the inflammation symptom at the local lesion position of the large intestine is relieved.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for treating ulcerative colitis and a preparation method thereof. Background technique [0002] Ulcerative colitis is an intestinal disease characterized by local inflammatory lesions of the colonic mucosa. The lesions are limited to the large intestinal mucosa and submucosa, located in the sigmoid colon and rectum, and can also extend to the descending colon or even the entire colon. With blood as the main symptom, the patient may experience gastrointestinal symptoms such as abdominal pain and diarrhea. At the same time, different accompanying symptoms may appear, such as headache, fever and vomiting. At present, the academic community believes that it is related to the patient's immune system. [0003] At present, the treatment drugs for ulcerative colitis include aminosalicylic acid preparations, glucocorticoids, immunosuppressants, biological pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P1/00A61P1/04A61P1/12A61P1/14A61P29/00A61P7/04
CPCA61K36/344A61K36/481A61K36/284A61K36/484A61K36/8994A61K36/736A61K36/62A61K36/756A61K36/752A61K36/233A61K36/718A61K36/232A61K36/63A61K36/71A61K36/65A61K36/285A61K36/185A61K36/73A61K36/84A61K36/9064A61K36/739A61K36/8984A61K36/538A61K36/489A61K36/39A61K36/43A61K36/54A61K36/66A61P1/00A61P1/04A61P1/12A61P1/14A61P29/00A61P7/04A61K2236/13A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00Y02A50/30
Inventor 林聪明
Owner ZHANGZHOU SHUIXIAN PHARMA CO LTD
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