Moisturizing or anti-atopic composition comprising fatty acid or fatty acid derivative
A composition and atopic technology, applied in the directions of drug combinations, medical preparations containing active ingredients, applications, etc., can solve the problems of stem and leaf physiological activity and rare ingredients, and achieve low cytotoxicity and moisturizing factor. The effect of increased production
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
manufacture example 1
[0044] Production Example 1. Production of carrot aerial part extract
[0045] After washing and drying the carrot aerial parts with distilled water, they were pulverized with a mixer to obtain a fine powder sample. About 10 times the sample weight of each carrot aerial fine powder (200 g) was added with a solvent in which ethanol and purified water were mixed at a ratio of 7:3, followed by two extractions. After the extraction was performed, filtration was carried out with a 400-mesh filter cloth, and then the obtained filtrate was 100% concentrated with a vacuum concentrator to obtain the carrot aerial part extract (65 g), which was used for test.
manufacture example 2
[0046] Production Example 2. Compound isolation from extract
[0047] After suspending the carrot aerial part extract (60 g) produced in the above-mentioned production example 1 in 1 L of distilled water, adding 1 L of n-hexane, and vigorously mixing, the n-hexane layer was fractionated using a separating funnel, followed by passing Reduced-pressure concentration and fractional distillation were performed to obtain a n-hexane fraction (3 g). Vacuum liquid chromatography (VLC) was performed in order to subdivide the fractions according to polarity, and a solvent of n-Hexane-ethyl acetate (n-Hexane-EtOAc) (0-50%) was performed. 200 mL were eluted with 3 or 5% increase in polarity each, resulting in 15 fractions (V1-V15). Among them, V3 (384 mg) was compound 1, and 74.5 mg and 96.8 mg of compound 2 were obtained in V7 (491.6 mg) and V8, respectively. 3 :MeOH=15:1) to obtain compound 3 (48.3 mg) and used in the experiment. For each compound, compound 1 (ethyl linoleate, Ethyl l...
preparation example 1
[0095] Formulation example 1. Manufacture of skin softening lotion
[0096] Ethyl linoleate 0.1% by weight
[0097] Alpha-linolenic acid 0.1% by weight
[0098] Linoleic acid monoglyceride 0.1% by weight
[0099] Butanediol 2.0% by weight
[0100] Propylene glycol 2.0% by weight
[0101] Acrylates / C10-C30 Alkyl Acrylate Crosspolymer 0.1 wt%
[0102] Polysorbate 80 0.4% by weight
[0103] Arginine 0.1% by weight
[0104] Xanthan gum 0.1% by weight
[0105] Hyaluronic acid 1.0% by weight
[0106] Appropriate amount of preservatives, colors and flavors
[0107] Add purified water to 100
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More