Protein WG-SP01 with immunomodulatory activity

A technology of immunomodulatory activity and immunomodulatory agent, applied in the field of protein engineering, can solve problems such as adverse effects on immune function, and achieve the effect of improving ATP activity and increasing proliferation ability
CN114805518APending Publication Date: 2022-07-29HENAN UNIV OF ANIMAL HUSBANDRY & ECONOMY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HENAN UNIV OF ANIMAL HUSBANDRY & ECONOMY
Publication Date
2022-07-29

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Abstract

The invention discloses an immunomodulatory active protein WG-SP01, and the protein WG-SP01 can activate the activity of LDH and ACP, so that macrophages of an organism are in an activated state; the ATP activity of lymphocytes can be obviously improved; the multiplication capacity of T lymphocytes and B lymphocytes of the spleen is obviously improved; the protein WG-SP01 has a remarkable immune regulation effect. Therefore, the protein WG-SP01 can be used as an active ingredient of an immunomodulator or an immunopotentiator for preparing medicines or functional foods for treating immune diseases such as systemic lupus erythematosus, rheumatoid arthritis, scleroderma and hyperthyroidism, and also can be used for other pharmaceuticals or functional foods with an immunoregulation effect.
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Description

technical field

[0001] The invention relates to the field of protein engineering, in particular to a protein WG-SP01 with immunomodulatory activity. Background technique

[0002] Immune diseases refer to diseases caused by the imbalance of immune regulation that affects the immune response of the body. Autoimmune diseases are mainly caused by the accumulation of a large number of immune cells and immunoglobulins produced by an excessive immune response, which damages normal tissues and causes lesions and functional impairments. If it occurs in the skin, it is allergic dermatitis and various skin lesions. If it occurs in the joints, it is arthritis. If it occurs in the kidneys, it is nephritis.

[0003] Common autoimmune diseases are: systemic lupus erythematosus, rheumatoid arthritis, scleroderma, hyperthyroidism, juvenile diabetes, idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, ulcerative colitis, and many disease, chronic liver disease...etc.

[0004] ...

Claims

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