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93 results about "Glass Syringe" patented technology

A device for the administration of parenteral drug products that consists of a rigid glass barrel fitted with septum with a plunger at one end and a seal or needle at the other end. The needle assembly may be part of the device or separate.

Injection Device

An injection device is described. A syringe 114 is received within a housing, the syringe having a bore terminating at a forward end in a hypodermic needle 118 and at a rearward end in a flared opening 210 in which a bung 134a having a bore 206 surrounded by a skirt 208 is inserted. A drive element 134 has a forward end consisting of a substantially flat annular region 200 that bears upon the skirt 208 of the bung 134a and surrounds a conical middle region 202 that is received in the bore 206 of the bung 134a. An actuator advances the drive element 134 so as to advance the bung 134a and discharge the contents of the syringe through the needle 118. The opening 210 in the rear of the glass syringe is flared by being provided with a radius. The combination of the radius at the opening 210 and the projecting conical middle region 202 of the drive element allows misalignments of the two to be managed during automated assembly. This is because the conical middle region 202 either pass straight into the opening 210 of the syringe, or contact the radius, which guides them towards the centre of the syringe bore. The radius and the substantially flat annular region 200 and the central conical portion 202 of the drive element 134 are so shaped and dimensioned that axial misalignment between the syringe 114 and the drive element 134 during assembly of the injection device are corrected by, firstly, the conical middle region 202 of the drive element 134 riding up the radius to a point at which, secondly, the substantially flat annular region 200 also makes contact with and rides up the radius, to align the drive element 134 in the bore of the syringe 114.
Owner:CILAG GMBH INT

Method for producing nano-fibre bracket material with levorotation polylactic acid as base material

The invention relates to a method for preparing a nanofiber bracket material using levorotatory polylactic acid as matrix. The method comprises the following steps: dissolving the levorotatory polylactic acid as the matrix in a solution of dichloromethane and dimethyl formamide, and stirring and centrifuging the mixture to obtain an electrostatic spinning solution; placing a polylactic acid solution into a 5 milliliter glass syringe, and applying high voltage on the glass syringe; advancing the levorotatory polylactic acid solution in the glass syringe; preparing the mixed solution into a nanofiber material film through a electrostatic spinning technology; and modifying the nanofiber material film to obtain the nanofiber bracket material of which the fiber diameter is between 50 and 500 nanometers and the fiber porosity is more than 90 percent. The method solves the defects that a PLLA porous bracket still has too long degradation time, and degradation products can cause tissue inflammations easily and the like. The method has the advantages of flexible texture, better water permeability and air permeability, excellent tissue compatibility, controllable biodegradability, and no antigenicity.
Owner:THE AFFILIATED DRUM TOWER HOSPITAL MEDICAL SCHOOL OF NANJING UNIV

Disposable self-shielding unit dose syringe guard

An improved guard for a medical cartridge, such as a unit dose pre-filled glass syringe, comprising a body for receiving the cartridge, and a shield slidably attached to the body which are pre-assembled and ready to receive a cartridge therein. The body has a mechanism on a proximal end thereof which holds the cartridge therein. The body and shield have cooperating detents and detent pockets which allow the shield to be directed distally, from an unguarded position in which the needle on the cartridge is uncovered for delivery of medication, to a guarded position in which the needle is permanently covered for disposal. The body may also include a substantially rectangular-shaped finger grip on its proximal end for receiving a similarly shaped proximal flange on the cartridge, whereby the cartridge is received in a predetermined orientation. The body may also include one or more ribs within the cavity for accommodating a cartridge with a large needle cap, such as a 0.5 mL capacity pre-filled syringe. In addition, the guard may include a finger grip plug lockably attachable to the proximal end of the body, and a plunger insertable through the finger grip plug to engage a piston in a cartridge not having its own plunger. The plunger may include a one-way locking member to prevent removal of the plunger from the finger grip plug after assembly.
Owner:SAFETY SYRINGES

Electrostatic spinning device for preparing axial orderly arranged tubes by means of magnetic field inducement

InactiveCN105200540ABending Instability SuppressionGood orientationFilament/thread formingFiberHigh pressure
The invention provides an electrostatic spinning device for preparing axial orderly arranged tubes by means of magnetic field inducement. The device can be used for preparing three-dimensional orderly arranged tubular tissue engineering scaffold materials. The device comprises a micro-injection pump, a reservoir, a conductive capillary tube, a direct-current high-voltage power supply, a receiving device and annular ferrite magnets, wherein the reservoir is a glass injector and fixed to the micro-injection pump, the micro-injection pump can accurately control spinning solution extrusion rate, the conductive capillary tube is a stainless steel injection needle with the top end ground flat, the receiving device is a roller connected with a motor, the positive pole of the direct-current high-voltage power supply is connected with the stainless steel injection needle, and the roller serving as the receiving device is grounded through a wire so that a high-voltage electric field can be generated between the head of the stainless steel injection needle and the receiving device; the roller is sleeved with a pair of annular ferrite magnets which rotate together with the roller, and the distance between the two magnets is 4-10 cm so that the receiving device can be in a stable magnetic field. Compared with the single roller method for preparing a tubular support, the device has the advantages that the orderliness of prepared fibers is improved greatly, and the application range of electrostatic spinning is widened.
Owner:BEIHANG UNIV

Pre-encapsulating glass syringe vacuum plugging machine

The invention discloses a pre-encapsulating glass syringe vacuum plugging machine which comprises a sealing box body, wherein the box body is provided with a door which can be opened, and a contact part of the door and a side plate of the box body is provided with a sealing piece; the side wall of the middle lower part in the box body is provided with a positioning tool plate, and a plugging mechanism is arranged above the positioning tool plate; the side surface of the box body is provided with a connector which is communicated with the interior of the box body; and the plugging mechanism and a vacuum generator are both connected with a controller. According to the pre-encapsulating glass syringe vacuum plugging machine, air in the lower part of liquid medicine in a glass syringe can all be exhausted to avoid the overflowing of the liquid medicine, and the lower edge of a rubber plug connected with a push rod in the glass syringe is just contacted with the upper surface of the liquid medicine, so that when the glass syringe is used by working personnel, after a packing is opened and a syringe needle is loaded, the syringe can be directly used by pushing the push rod without worrying about the problem that the liquid medicine contains bubbles; and the pre-encapsulating glass syringe vacuum plugging machine has the advantages of time saving, working efficiency improvement and improvement of the liquid medicine use safety and is suitable for long-distance transport and long-time storage.
Owner:山东淄博民康药业包装有限公司

Pre-encapsulating glass syringe vacuum plugging method

The invention discloses a pre-encapsulating glass syringe vacuum plugging method which comprises the following steps of: (1) loading a liquid product tool plate into a box; (2) tool positioning: clamping a part of edge of a glass syringe tool plate in a stage of positioning clamp trough of a positioning tool plate; (3) rubber plug charging tool plate positioning: placing a rubber plug tool plate filled with rubber plugs on the upper part of the glass syringe tool plate, and clamping a part of edge of the rubber plug tool plate in the other stage of positioning clamp trough of the positioning tool plate; (4) closing a door of the box body; (5) pumping with vacuum to eliminate liquid medicine bubbles; (6) releasing pressure and charging plugs; and (7) encapsulating. According to the pre-encapsulating glass syringe vacuum plugging method, air in the lower part of the liquid medicine in a glass syringe can all be exhausted to avoid the overflowing of the liquid medicine, and the lower edge of the rubber plug connected with a push rod in the a syringe is just contacted with the upper surface of the liquid medicine, so that when the glass syringe is used, after a packing is opened and a syringe needle is loaded, the syringe can be directly used by pushing the push rod, and the pre-encapsulating glass syringe vacuum plugging method has the advantages of time saving, working efficiency improvement, use safety improvement of the liquid medicine and is suitable for long-distance transport and long-time storage.
Owner:山东淄博民康药业包装有限公司

High-elasticity PHA porous fiber material and preparing method thereof

The invention relates to a high-elasticity PHA porous fiber material and a preparing method of the high-elasticity PHA porous fiber material. The method is characterized by comprising the steps that (1), PHA (P3HB4HB, 10-18 mol%4HB) is added into a mixed solvent of chloroform and acetone under the condition of stirring, and a mixed solution is obtained through stirring; (2), the temperature of the mixed solution is risen to 50 DEG C-80 DEG C under the condition of stirring, and through sufficiently stirring the mixed solution for 5-8 minutes, a P3HB4HB electrostatic spinning solution evenly dissolved is obtained, wherein the concentration of polymer is 6 wt%-12 wt%; (3), the P3HB4HB spinning solution is transferred into a glass syringe, then the glass syringe where the P3HB4HB spinning solution is contained is fixed to an electrostatic spinning device for electrostatic spinning, collected fibrous membranes are dried for 6-12 hours under a vacuum condition at the temperature of 40 DEG C-60 DEG C, and the high-elasticity P3HB4HB porous fiber membrane is obtained through preparation, wherein the elongation at break can reach above 500%. The preparing process is simple, controllable and efficient, biological degradability and biological compatibility are good, the diameter and elongation mechanical property of fibers are adjustable within a certain range, and the high-elasticity PHA porous fiber material has the good elasticity and the high elongation at break.
Owner:JIANGNAN UNIV

Pipettor close performance detection device

The invention relates to a pipettor close performance detection device. The detection device is formed by a transparent reagent bottle, a glass syringe, a right latex tube, a right three-way valve, a right glass tube, a vacuum pressure gauge, a left glass tube, a left three-way valve, a left latex tube, a liquid-absorbing nozzle and a soft rubber bottle plug. A pipettor close performance detection method of the pipettor close performance detection device is characterized by adjusting a pipettor to be detected to nominal capacity; installing the liquid-absorbing nozzle to the pipettor to be detected and screwing the liquid-absorbing nozzle tightly; carrying out connection according to the installation connection step; adjusting rotary knobs of the left and right three-way valves and extracting air with the glass syringe and repeating the operation until a pointer of the vacuum pressure gauge points to -0.04 MPa; and carrying out close performance detection of the pipettor to be detected through a closed loop formed by the pipettor to be detected, the left three-way valve, the transparent reagent bottle, the vacuum pressure gauge and the b end of the right three-way valve in sequence. The detection device solves the problems that it is troublesome and not easy to carry out the detection and efficiency is not high when carrying out close performance detection on the pipettor.
Owner:ZUNYI INST OF PROD QUALITY INSPECTION & TESTING

Method for preparing microencapsulated drink of Nanguo pear liver-protecting anti-alcohol agent

InactiveCN101756312BBright colorStrong pear fragranceFood preparationWater bathsMixed materials
The invention relates to a method for preparing a microencapsulated drink of a Nanguo pear liver-protecting anti-alcohol agent, which is particularly used for Nanguo pear fruit and provides a theoretical basis for quantification of ethanol and acetaldehyde dehydrogenase in Nanguo pear liver-protecting anti-alcohol drink production. The process of the method comprises: raw material selection, washing, block cutting, water-bath soakage, ice-bath grinding, ice-bath homogenization, one-hour 0 to 4 DEG C extraction, 15-minute 400-rpm centrifugation, freezing concentration, the preparation of enteric microencapsulates of mixed concentrates of the ethanol, the acetaldehyde dehydrogenase and the like and the preparation of the drink by blending according to required package. The preparation of enteric microencapsulates of the mixed concentrates of the ethanol, the acetaldehyde dehydrogenase and the like is implemented by the following steps: mixing a wet enzyme paste mixture and 10 percent gelatin and 5 percent xanthan gum in a volume ratio of 1:5.5; fully and uniformly mixing the materials; uniformly mixing the mixed materials with a certain amount of 2-percent sodium alga acid; injecting the mixed solution into cooled solution of CaCl2 by using a glass syringe with a No.4 syringe needle to perform emulsification for 10 minutes with a stirring speed or 400rpm to obtain colloid-calcium alginate double-layer gel beads; subjecting the colloid-calcium alginate double-layer gel beads to a film forming reaction with solution of chitosan for 30 minutes; removing unreacted chitosan by washing to obtain wet Nanguo pear-dehydrogenase combined microencapsulate gel beads; and placing the microencapsulated dehydrogenase microencapsulate gel beads in a regulation tank for regulating concentration according to an anti-alcohol ratio, adding a proper amount of sugar and other seasoning matters, homogenizing the mixture, and automatically filling and sealing the resulting product.
Owner:LIAONING UNIVERSITY OF PETROLEUM AND CHEMICAL TECHNOLOGY
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