Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of 2-chloro-1, 1-difluoroethane

A technology of difluoroethane and fluorination, which is applied in the field of preparation of 2-chloro-1,1-difluoroethane, can solve the problems of long synthesis route, complex process, harsh reaction conditions, etc. Simple, high reaction yield effect

Pending Publication Date: 2022-08-05
SHANDONG HUAAN NEW MATERIAL
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The object of the present invention is to provide a synthetic route with simple process and high product yield in view of the problems of long synthetic route, complex process and harsh reaction conditions in the preparation method of 2-chloro-1,1-difluoroethane in the prior art. A new method for the preparation of 2-chloro-1,1-difluoroethane with high yield and high purity and continuous industrial production

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of 2-chloro-1, 1-difluoroethane

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] (1) Preparation of isomerization catalyst: weigh 300 g of activated alumina, fill it into a SUS-316 reaction tube with an inner diameter of 30 mm and a length of 100 mm, and set it in a tubular electric furnace. The temperature was raised to 400°C at 2-5°C / min, and kept at 400°C for 10-20 h for dehydration. Then 20L / h of nitrogen / HF mixed gas of 5 / 1 (volume / volume) was passed through, and the alumina catalyst was fluorinated and circulated for 24 hours, and the bed temperature was controlled to ±5°C. If the bed temperature changed greatly, The nitrogen ratio can be increased until it is all nitrogen. When the bed is stable, gradually reduce the nitrogen ratio until all the gas is HF, and keep it for 100h. Heating was stopped, HF was turned off, nitrogen was started, and the nitrogen flow was about 10 L / h, and the catalyst was naturally cooled to room temperature to complete the catalyst preparation.

[0039] (2) Preparation of crude 2-chloro-1,1-difluoroethane: 65g (6...

Embodiment 2

[0042] On the basis of Example 1, the reaction temperature of step (2) was changed to 250°C, N 2 : R142b=10:1 (mol), the space velocity is 330 / h, after half an hour of reaction, samples were taken at the outlet of the reactor to detect the content of each component. The reaction results are shown in Table 1.

Embodiment 3

[0044] On the basis of Example 1, the reaction temperature was changed to 200°C, N 2 : R142b=5:1 (mol), the space velocity is 330 / h, and the content of each component is detected by sampling at the reactor outlet after half an hour of reaction. The reaction results are shown in Table 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method of 2-chloro-1, 1-difluoroethane, and belongs to the technical field of organic fluorine chemical industry. The preparation method of the 2-chloro-1, 1-difluoroethane comprises the following steps: firstly preparing an isomerization catalyst, isomerizing 1, 1-difluoro-1-chloroethane by using the catalyst to prepare the 2-chloro-1, 1-difluoroethane, then separating to obtain a finished product of the 2-chloro-1, 1-difluoroethane, recovering the unreacted 1, 1-difluoro-1-chloroethane to serve as a raw material, and continuing to react. The preparation method of 2-chloro-1, 1-difluoroethane has the advantages of abundant raw material sources, high reaction yield, simple process, realization of industrial continuous production, easy product separation and the like, reduces the production cost, and is safe and environment-friendly.

Description

technical field [0001] The invention belongs to the technical field of organic fluorine chemicals, in particular to a preparation method of 2-chloro-1,1-difluoroethane. Background technique [0002] 2-Chloro-1,1-difluoroethane (2-chloro-1,1-difluoroethane, referred to as HCFC-142) is a colorless transparent liquid, the molecular formula is C 2 H 3 ClF 2 , molecular weight: 100.5, CAS number: 338-65-8, boiling point: 36°C, melting point: -82.13°C, density: 1.312 g / mL (15°C), refractive index: 1.3528 (15°C). Critical temperature: 204.76 ℃, critical pressure: 4.277 MPa. It is an important aliphatic fluorine-containing intermediate, an intermediate product for the preparation of 2,2-difluoroethanol, etc., and can also be used in the field of aerosols and foaming agents for cleaning, drying and degreasing solid surfaces. , medicine, refrigerant and other aspects also have a wide range of uses. [0003] At present, the synthesis methods of 2-chloro-1,1-difluoroethane in the p...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07C17/358C07C19/12B01J27/125
CPCC07C17/358B01J27/125C07C19/12Y02P20/584
Inventor 王瑞英李丕永邹冉王永千张丽平
Owner SHANDONG HUAAN NEW MATERIAL
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com