Solar radiation protection composition

A compound, polyphenolic compound technology, used in cosmetics, skin care preparations, cosmetic preparations, etc., to reduce skin cancer and facilitate separation

Inactive Publication Date: 2002-04-24
NOUVAB
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

To date, these organisms have not been exploited as a source of sun-shielding compounds applied to human skin

Method used

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  • Solar radiation protection composition
  • Solar radiation protection composition
  • Solar radiation protection composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Example 1 Identification of sun-shielding compounds

[0070] We have pointed out that when cyanobacteria and Plectonema boryanum are exposed to too much light radiation (and thus the photosynthetic system is exposed to too much light radiation), the culture will increase the production of the following three important sun-shielding factors: carotenoids (cyanobacteria lutein) , Bifidobacterium and Bacterosporine amino acids. When these cyanobacteria are exposed to excessive radiation, ( figure 1 .15 / 150), and the control group ( figure 1 .29 / 150), the body produces 5 times or more cyanobacteria lutein. This response is specific to cyanobacteria lutein, because the other major carotenoids, β-carotene and zeaxanthin show only minimal increases. In addition, when these cultures are reduced from radiation ( figure 1 .15 / 6), cyanobacteria lutein was reduced to a level equivalent to that of the control group ( figure 1 , Compare 15 / 6 and 29 / 150). In addit...

Embodiment 2

[0080] Example 2 Modification of Cyanobacteria Sunshine Shielding Factors and Related Sunshine Shielding Factors

[0081] Compounds similar to carotenoids, polyphenol compounds and mycosporine amino acids as well as light-absorbing amino acids such as tyrosine (Tyr) and tryptophan (Trp) described in the present invention can be applied to the composition. The derivative can be prepared by the following methods, steps, or other steps. For example, the carbonyl groups of bifidin and mycosporin can be reduced or reductive amination can be achieved by administration of alcohol and amine compounds. These alcohols and amine-based compounds can optionally be further derivatized by reaction. For example, acid halides, acyl acyl, formate and isocyanate can provide esters, amides, ureas or the like. Amino compounds can also be reductively alkylated from subunit amine groups with aldehydes and ketones. The derivatization reactions of these alcohols and amines are qu...

Embodiment 4

[0085] Example 4 Preparation of Sunshine Shielding Components

[0086] In the past two decades, a large number of effective methods for formulating solar radiation protection products have emerged (Flick, 1984, Cosmetic and Toiletry Formulations, pp513, Noyes Pub., New Jersey; Casparro et al., 1998, Photochem.Photobiol.68 : 243). Sunshine shielding products can contain a wide range of ingredients. These ingredients do not absorb solar radiation, but they can help control the characteristics of the product. These characteristics include film hardness, transparency, anti-friction, water resistance, and uniformity. The sun-shielding factor of the present invention, carotenoids, such as cyanobacteria lutein, polyphenolic compounds such as bifidophytes and mycosporine amino acids or derivatives of these compounds, are formulated together with known compounds to obtain the best Performance of sun shielding function (Sun Care Products Formulary, 1998, Cosmetics...

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PUM

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Abstract

The invention relates to sunscreen compositions for humans including naturally occurring sunscreen agents from plants, algae, cyanobacteria, fungi and bacteria that protect against exposure to solar radiation. The active sunscreen agents are compounds that naturally occur in plants, algae, cyanobacteria, fungi and bacteria and derivatives of these compounds.

Description

Technical field [0001] The invention relates to a formula for protecting humans and articles from sunlight radiation damage. The invention also relates to active ingredients and their derivatives extracted from plants, algae and cyanobacteria, which can avoid damage caused by sunlight. Background technique [0002] Different layers of the earth’s atmosphere can absorb most of the solar radiation reaching the earth, especially the ozone layer can absorb high-energy ultraviolet rays. Among the sunlight radiation related to biology that reaches the surface of the earth, only 2% of the radiation is ultraviolet B (UV-B), and its characteristic wavelength range is 280-315nm. The rest are mainly ultraviolet A (UV-A), whose characteristic wavelength range is 315-400nm; visible light (wavelength range is 400-700nm), and infrared (characteristic wavelength greater than 740nm). The destruction of the stratospheric ozone layer by humans (Madroinichetal, 1995. Ambio 24:143) has led to an incr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/44A61K8/49A61K8/99A61Q17/04C12P7/22C12P13/04C12P23/00
CPCA61K8/602A61K8/975C12P23/00A61K8/97C12P13/04A61Q17/04C12P7/22A61K8/99A61K8/492A61K8/44
Inventor 罗曼·汉勒玛瑞拉·克罗尔亚历山大·伊万诺夫法勒·撒汉
Owner NOUVAB
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