Pharmaceutical composition for sustained or continuous releasing therapeutic active components

An active ingredient, sustained release technology, applied in the direction of drug combinations, organic active ingredients, medical formulations containing active ingredients, etc., can solve the problem of drug release at a meaningful and beneficial rate, and rarely reported drug release with limited water solubility and other problems, to achieve the effects of easy mass production, improved drug release, and easy dissolution
CN1622799AInactive Publication Date: 2005-06-01科学和工业研究委员会
22 Cites 13 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
科学和工业研究委员会
Publication Date
2005-06-01
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

A pharmaceutical composition useful for sustained / extended release of a therapeutically active ingredient to an environment of use, said composition comprises a tablet core composition consists of a therapeutically active ingredient that is weakly acidic in nature and has a limited solubility in the aqueous environment, said the therapeutically active ingredient is in immediate contact with the agents that are capable of improving the solubility of the agent within the core, for e.g., by changing the micro environmental pH of the core and the tablet core is surrounded by a release rate controlling membrane consisting of a semi-permeable membrane forming polymer, permeable membrane forming polymer, and at least one plasticizer capable of modulating the film formation properties of the polymers.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to pharmaceutical compositions for sustained / delayed release of therapeutically active ingredients.

[0002] The present invention relates to novel, useful pharmaceutical compositions for the sustained release of therapeutically active ingredients into the environment of use. More particularly, the present invention relates to oral pharmaceutical compositions that function according to the principle of osmotic pressure, the principle of diffusion, or a combination of both. The pharmaceutical composition of the present invention comprises a tablet core containing a therapeutically active ingredient, a solubility modifier, an osmagent and other conventional excipients. The tablet core is coated with a controlled-release membrane wall made of a semipermeable membrane-forming polymer and a permeable membrane-forming polymer. The therapeutically active ingredients of the present invention are slightly acidic and have limited so...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More