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Nano silver antiseptic gel for treating women's genital tract infection and its prepn and application

A technology of nano silver gel and reproductive tract infection, applied in the field of external use of antibacterial nano silver gel, can solve the problems of complex process, complex composition, no public treatment of women's lower reproductive tract infection, etc., and achieves good permeability and fast onset. , excellent curative effect

Inactive Publication Date: 2005-09-28
SHENZHEN AGT PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the Chinese invention patent application CN01129507.4, the nano-silver prostatitis anti-bacterial and anti-inflammatory gel made by using the above-mentioned antibacterial nano-silver powder as an active ingredient is disclosed. Active agent, dispersant, the composition is more complex, and in the process of processing, heating is required, and the process is more complicated
[0007] Korean patent PCT / KR2003 / 002855 discloses a nano-silver colloid, the nano-particle size is 1-20 nanometers, the carrier of the colloid is silica gel, the silver content of the nano-silver colloid can reach 1000-50000ppm, the nano-silver colloid It has good antibacterial performance and is used in various fibers or daily necessities as an antibacterial and disinfectant component, but it has not been publicly used to treat women's lower reproductive tract infections

Method used

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  • Nano silver antiseptic gel for treating women's genital tract infection and its prepn and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Ingredients: nano-silver colloid: containing nano-silver particle size 1-20 nm, nano-silver content 35000ppm, 10g;

[0036] Polyethylene glycol: 10g

[0037] Glycerin: 10g

[0038] Deionized water: 970g

[0039] Sodium dodecyl sulfonate: 0.005g

[0040] Add the above raw materials into the blender, stir for 2 hours, make it mix evenly, and form a gel; then pack it into the gel dispenser, add outer packaging, and obtain a gel containing 350ppm of nano-silver, each gel The container contains 3g of product. The gel giver, such as figure 1 As shown, it is mainly composed of cap 1, gel supply body 2, and push rod 3. The gel supply body 2 is a hollow cylinder with a length of 10-12cm and an outer diameter of 11mm. The front end is a spherical surface , there is a hole on the spherical surface, a cap 1 is placed on the hole, antibacterial nano-silver gel is housed in the gel body 2, and a push rod 3 is inserted in the middle of the gel body 2, and the push rod 3 can be us...

Embodiment 2

[0042] Ingredients: nano-silver colloid: containing nano-silver particle size 1-20 nm, nano-silver content 4000ppm, 10g;

[0043] Polycarbophil: 20g

[0044] Glycerin: 10g

[0045] Deionized water: 960g

[0046] Sodium dodecyl sulfate: 0.003g

[0047] Other conditions were the same as in Example 1, except that the stirring time was 1 hour to obtain a gel containing 40 ppm of nanosilver.

Embodiment 3

[0049] Ingredients: nano-silver colloid: containing nano-silver particle size 1-20 nm, nano-silver content 1000ppm, 10g;

[0050] Carbomer: 30g

[0051] Glycerin: 10g

[0052] Deionized water: 950g

[0053] Sodium dodecyl sulfate: 0.001g

[0054] Other conditions are with embodiment 1. Only the stirring time is 0.5 hour, and a gel containing 10 ppm of nano-silver is obtained.

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Abstract

The present invention discloses one kind of nanometer antiseptic silver gel for external application to treat women's genital tract infection. The nanometer antiseptic silver gel contains nanometer silver colloid of silver particles in size 1-20 nm, pharmaceutically acceptable excipient and diluent. The present invention also discloses the preparation process and application of the gel. The product of the present invention is applied through vagina to treat vaginitis, cervicitis or mixed infection, and may be used as externally applied medicine for treating skin infection and surgical infection and as the antiseptic component in cosmetics.

Description

technical field [0001] The invention relates to a medicine for treating women's lower reproductive tract infection, in particular to an external antibacterial nano-silver gel for treating women's lower reproductive tract infection. The invention also relates to the preparation method and application of the medicine. Background technique [0002] Women's lower reproductive tract infections, mainly vaginitis and cervicitis, have a high incidence and have a great impact on the physical and mental health of women and their family members. At present, there are many therapeutic products on the market, which are divided into direct administration or indirect administration. Drug type, but its active ingredient is common broad-spectrum antibacterial antibiotics, long-term use, prone to drug resistance, and will have side effects on the human body, so the general treatment effect is not good, the treatment cycle is long, and the recurrence rate is high. [0003] Skin disease is als...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K33/38A61P15/02
Inventor 陈虎
Owner SHENZHEN AGT PHARM
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