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Flavone composition for sobering and liver protection and its use

A technology for detoxifying and protecting the liver and a composition is applied in the field of preventing and treating injuries caused by excessive drinking, and can solve problems such as injuries, increasing family and social burdens, and the like

Inactive Publication Date: 2005-10-19
SHANXI PUDE PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Excessive drinking has serious harmful effects on health. Studies have shown that excessive drinking can lead to liver cirrhosis, liver cancer, high blood pressure, stroke and other diseases. It also includes injuries in traffic accidents caused by drunk driving, which increases the family and society. burden

Method used

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  • Flavone composition for sobering and liver protection and its use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1, the preparation of flavone composition phospholipid solid dispersion

[0037] Proportion of main ingredients:

[0038] Puerarin 100g

[0039] Silymarin 100g

[0040] Soy Lecithin 20g

[0041] Weigh the main ingredient and auxiliary material soybean lecithin according to the above ratio, put it in a 2000ml round bottom flask, add 800ml of 95% ethanol, heat until all the substances are dissolved, evaporate the solvent under reduced pressure, and dry to obtain the solid dispersion of the flavonoid composition .

Embodiment 2

[0042]Embodiment 2, flavone composition tablet preparation 1

[0043] Tablet prescription:

[0044] Puerarin 200g

[0045] Silymarin 100g

[0046] Microcrystalline Cellulose 75g

[0047] Lactose 80g

[0048] Hypromellose 25g

[0049] 95% ethanol q.s.

[0050] Croscarmellose Sodium 25g

[0051] Micronized silica gel 3g

[0052] Made into 1000 pieces

[0053] Preparation method: according to the above preparation prescription, weigh the main ingredients puerarin and silymarin, add microcrystalline cellulose, lactose and 15g hydroxypropyl cellulose, granulate with 95% ethanol, dry at 60°C, and granulate; add the rest of the auxiliary materials and mix Press evenly and make 1000 tablets.

Embodiment 3

[0054] Embodiment 3, flavone composition tablet preparation 2

[0055] Tablet prescription:

[0056] Puerarin 240g

[0057] Silybin 60g

[0058] Vc 20g

[0059] Inosine 50g

[0060] Microcrystalline Cellulose 75g

[0061] 75g pregelatinized starch

[0062] Hypromellose 25g

[0063] Calcium sulfate 50g

[0064] Micronized silica gel 3g

[0065] Made into 1000 pieces

[0066] Preparation method: according to the above preparation prescription, weigh the main drug and pass through a 100-mesh sieve, and pass the auxiliary materials through a 100-mesh sieve, fully mix the sieved main drug and auxiliary materials, directly compress tablets, make 1000 tablets, pack, and get ready.

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PUM

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Abstract

The present invention discloses a kind of flavone composition with the function of reducing the body damage caused by excessive indigestion of alcohol obviously, and the composition consists of pueraria flavonid and silybum marianum flavone. Research shows that pueraria flavonid and silybum marianum flavone have obvious cooperative effects of resisting oxidation, protecting liver and promoting elimination of alcohol in body. The present invention also discloses the application of the composition in health food and medicine.

Description

technical field [0001] The invention discloses a flavonoid composition used in the field of medicine and health food, and specifically relates to the application of the composition in different preparation carriers to prevent and treat damage caused by excessive drinking. Background technique [0002] Drinking alcohol is an ancient and common social custom with a long tradition in China. my country is one of the first countries in the world to start brewing wine. In the Xia Dynasty more than 4,000 years ago, there was a record of using grain as raw material to brew wine. At present, China is still the country with the largest production and sales volume of alcoholic beverages in the world. Accompanied by the strong growth of China's economy, the production and sales of alcoholic beverages have increased by more than 25% every year. [0003] Moderate alcohol intake can reduce the inhibitory function of the brain, thereby achieving the effect of physical and mental relaxatio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K9/10A61K9/16A61K9/20A61K9/46A61K9/48A61K31/352A61K31/7048A61P1/16A61P25/32
Inventor 董诗文
Owner SHANXI PUDE PHARMA CO LTD
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