Bi-triazole compound, preparation method and application thereof

A compound, bitriazole technology, applied in the field of bitriazole compound and its preparation, to achieve the effect of simple preparation
CN1687059AInactive Publication Date: 2005-10-26WUHAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
WUHAN UNIV
Publication Date
2005-10-26
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to a triazole compound. Said invention provides its general formula. Its preparation method includes the following steps: using 5-triazo-1,2,4 triazol-3-acyl methyl ester and propiolic alcohol ester acetate, p-amyl phenylacetylene, syclohexanol alkyne, cyclohexene alkyne or methoxyphenyl acetylene, and making them be reacted in the tetrahydrofuran or mixed solvent of tetrahydrofuran and water at 10-100 deg.C under the action of Cu(I) catalyst so as to obtain the required triazole compound. Said triazole compound has the activity for directly inhibiting plant virus, in particular inhibiting tobacco mosaic virus.
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Description

technical field

[0001] The invention relates to a bitriazole compound, a preparation method and application thereof, and belongs to the fields of organic chemistry and biochemistry. Background technique

[0002] Plant viral diseases are known as "plant cancers". The proportion of plant diseases is second only to fungal diseases, and they pose a serious threat to agricultural production. Related research is in the ascendant (Whitham, 2004). It is estimated that the annual loss caused by tobacco mosaic virus (Tobacco mosaic virus, TMV) in the world is more than 100 million US dollars. Since viruses are obligately parasitic in plant cells, the materials, energy and places required for their replication are completely dependent on the host, and plants do not have a complete immune metabolism system, making the prevention and treatment of plant virus diseases particularly difficult. In order to effectively prevent and treat plant virus diseases, people have carried out beneficia...

Claims

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