Method for inducing pluripotent stem cells and pluripotent stem cells prepared by said method

US20160215269A1Inactive Publication Date: 2016-07-28AMOREPACIFIC CORP +1

Patent Information

Authority / Receiving Office
US ยท United States
Current Assignee / Owner
AMOREPACIFIC CORP
Publication Date
2016-07-28
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The present disclosure relates to a method for inducing pluripotent stem cells by inducing reprogramming and / or dedifferentiation of differentiated adult cells using shikimic acid, a plant extract or plant stem cells containing shikimic acid and an extract of dedifferentiated stem cells (callus), pluripotent stem cells prepared by the method and a composition containing the pluripotent stem cells. In accordance with the present disclosure, ethical concerns implicated with the use of eggs to prepare pluripotent stem cells such as embryonic stem cell can be resolved. And, because the plant stem cell extract unharmful to human is used, pluripotent stem cells with proven safety can be prepared and they may be used to develop immunocompatible cell therapy agents suited for individuals. In addition, by pluripotent stem cells from individuals having diseases, the present disclosure will be very useful in studying the cause of diseases and devolving therapeutic strategy.
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Description

TECHNICAL FIELD

[0001] The present disclosure relates to a method for inducing pluripotent stem cells by reprogramming and / or dedifferentiating a differentiated adult cells, pluripotent stem cells prepared by the method and a composition containing the pluripotent stem cells.

[0002] The present disclosure also relates to a pharmaceutical composition or a cosmetic composition containing pluripotent stem cells.

[0003] The present disclosure also relates to a composition for activating stem cells, proliferating skin cells, regenerating skin or anti-aging.BACKGROUND ART

[0004] Stem cells are undifferentiated cells that can differentiate into various types of cells constituting biological tissues and can be obtained from the tissues of embryos, fetuses and adults. Among the different cell types of the stem cell, pluripotent stem cells refer to the stem cells that can differentiate into any of the three germ layers, i.e., the endoderm, mesoderm and ectoderm.

[0005] The stem cells can be classified ...

Claims

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