Methods for producing an oralsuspension of teichoplanin or teichoplanin analogs

a technology of teichoplanin and oral suspension, which is applied in the directions of peptide delivery, emulsion delivery, saccharide peptide ingredients, etc., can solve the problems of inconvenient reconstitution process for both the pharmacist and the patient in need of teichoplanin treatment, incomplete administration of dose, and decreased patient compliance, so as to improve patient compliance, taste and stability, and reduce the ability to swallow
US20170065671A1Inactive Publication Date: 2017-03-09MAHER ILLYA KEITH
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
MAHER ILLYA KEITH
Publication Date
2017-03-09
Estimated Expiration
Not applicable · inactive patent

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Abstract

A stable suspension of teicoplanin and one or more pharmaceutically acceptable additives and method for preparation wherein the teicoplanin is mixed with an aqueous or non aqueous suspension base and pharmaceutically acceptable additives and wherein the teicoplanin is milled to obtain a homogeneously dispersed suspension.
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Description

RELATED APPLICATIONS

[0001] This application claims priority to U.S. Provisional Application No. 62 / 215,425 filed Apr. 30, 2015. The entire contents of the above application are hereby incorporated by reference as though fully set forth herein.FIELD

[0002] The present invention relates to the field of medicinal preparations containing peptides. More specifically, the present invention relates to preparations of teicoplanin, which is an antibiotic of the glycopeptide family, more particularly of the ristocetin type.BACKGROUND

[0003] Teicoplanin is an antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, Enterococcus faecalis and Clostridium. It is a semisynthetic glycopeptide antibiotic with a spectrum of activity similar to vancomycin. Its mechanism of action is to inhibit the polymerization of cell wall components in bacterial cell wall synthesis.

[0004] Teicoplanin is complex glycoprotein mix...

Claims

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