Feed additive composition

Abstract

A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-β-d-xylanase) and a β-glucanase (and optionally a further fibre degrading enzyme), wherein the DFM is selected from the group consisting of an enzyme producing strain; a C5 sugar-fermenting strain; a short-chain fatty acid-producing strain; a fibrolytic, endogenous microflora-promoting strain; or combinations thereof. The DFM may be selected from the group consisting of: Bacillus subtilis AGTP BS3BP5, Bacillus subtilis AGTP BS442, B. subtilis AGTP BS521, B. subtilis AGTP BS918, Bacillus subtilis AGTP BS1013, B. subtilis AGTP BS1069, B. subtilis AGTP 944, B. pumilus AGTP BS 1068 or B. pumilus KX11-1, Enterococcus faecium ID7, Propionibacterium acidipropionici P169, Lactobacillus rhamnosus CNCM-I-3698, Lactobacillus farciminis CNCM-I-3699, a strain having all the characteristics thereof, any derivative or variant thereof, and combinations thereof and the further fibre degrading enzyme may be selected from the group consisting of a cellobiohydrolase (E.C. 3.2.1.176 and E.C. 3.2.1.91), a β-glucosidase (E.C. 3.2.1.21), a β-xylosidase (E.C. 3.2.1.37), a feruloyl esterase (E.C. 3.1.1.73), an α-arabinofuranosidase (E.C. 3.2.1.55), a pectinase (e.g. an endopolygalacturonase (E.C. 3.2.1.15), an exopolygalacturonase (E.C. 3.2.1.67) or a pectate lyase (E.C. 4.2.2.2)), or combinations thereof.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]The present application is a divisional of U.S. patent application Ser. No. 14 / 609,911, filed Jan. 30, 2015, which is a 371 of International Patent Application No. PCT / EP2013 / 066254, filed Aug. 2, 2013, which claims priority to U.S. Provisional Patent Application No. 61 / 679,084, which was filed on Aug. 3, 2012, and all of which are herein incorporated by reference.FIELD OF INVENTION[0002]The present invention relates to methods for improving feed compositions using a specific direct fed microbial in combination with a xylanase and a β-glucanase, and to a feed additive composition comprising a direct fed microbial in combination with a xylanase and a β-glucanase. The present invention further relates to uses and kits.BACKGROUND OF THE INVENTION[0003]Supplemental enzymes are used as additives to animal feed, particularly poultry and swine feeds, as a means to improve nutrient utilization and production performance characteristics. Enzyme bl...

AI Technical Summary

Benefits of technology

The present invention relates to a combination of enzymes and specific direct fed-microorganisms (DFMs) that can improve the conversion of dietary material derived from plant cell wall particles to short-chain fatty acids (SCFAs) in the gastrointestinal tract (GIT) of animals. The combination of enzymes includes xylanase and β-glucanase, which can solubilize fibre from the diet, leading to improved animal performance. The DFMs can produce enzymes and promote the growth of fibrolytic microflora in the GIT, which can further enhance the conversion of NSPs to SCFAs. The combination of enzymes and DFMs can also optimize energy value from plant products and improve the efficiency of animal performance.

Problems solved by technology

This solubilisation of hemicellulose would not always be sufficient to increase performance because C5-sugars released are not an efficient source of energy for animals when they are absorbed (Savory C., J. Br. J. Nut. 1992, 67: 103-114), but they are a more efficient source of energy when converted into short chain fatty acids (SCFA) either by microorganisms in the GIT or by DFMs.

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