Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

49 results about "Kidney Insufficiency" patented technology

Alprostadil composite medicine, preparation method thereof, quality controlling method thereof, and purpose thereof

The invention relates to an alprostadil composite medicine comprising high-purity alprostadil and a mixture of aspirin-DL-lysine and sodium salicylate, wherein a weight ratio of aspirin-DL-lysine to sodium salicylate is 90-95:5-10. The invention also provides a weight ratio of the raw materials of the composite medicine. The invention also provides a preparation method of the alprostadil composite medicine, and a quality controlling method of the alprostadil composite medicine. With a pharmaceutically acceptable alprostadil composite medicine dosage, the medicine can be prepared into lyophilized injections, oral preparations, aerosols, suppositories, or enemas of the acceptable alprostadil composite medicine. The invention discloses chromatographic conditions for determining the contents of alprostadil, prostaglandin A1 and prostaglandin B1. Three peaks before an alprostadil peak are characteristic peaks of alprostadil composite medicine auxiliary materials. The alprostadil composite medicine is used for treating and preventing diseases such as coronary heart disease, myocardial infarction, brain infarction, hypertension, hyperlipemia, atherosclerosis, angiitis, tumour, hepatitis, diabetic angiopathies, kidney insufficiency, bronchial asthma, pancreatitis, gastric ulcer, and vertebrobasilar insufficiency.
Owner:蔡海德

Kidney-tonifying, collateral-dredging and brain-nourishing paste and preparation method thereof

The invention discloses kidney-tonifying, collateral-dredging and brain-nourishing paste and a preparation method thereof. The kidney-tonifying, collateral-dredging and brain-nourishing paste is characterized by being prepared from the following crude drugs: radix rehmanniae preparata, rhizoma dioscoreae, fructus corni, poria cocos, cortex moutan, rhizoma alismatis, fructus lycii, semen cuscutae,ganoderma lucidum, fructus ligustri lucidi, herba ecliptae, fructus mori albae, mantidis ootheca, fructus alpiniae oxyphyllae, raw radix astragali seu hedysari, radix polygonati officinalis, lily bulb, semen persicae, safflower, red paeony root, rhizoma chuanxiong, radix bupleuri, fried fructus aurantii, radix achyranthis bidentatae, radix platycodonis, rhizoma anemones altaicae, prepared radix polygalae, rhizoma atractylodis, bighead atractylodes rhizome, semen nelumbinis, scorched fructus crataegi, medicated leaven, fried rice sprout, fried malt, pericarpium citri reticulatae, radix curcumae, radix clematidis, Chinese angelica root, processed rhizoma pinelliae, fructus liquidambaris, radix et rhizoma salviae miltiorrhizae, fructus amomi, American ginseng, syngnathus, hippocampus, tortoise-plastron glue, turtle shell glue, radix notoginseng, bulbus fritillariae cirrhosae, sugar and yellow rice wine. The kidney-tonifying, collateral-dredging and brain-nourishing paste is used for treating kidney insufficiency and essence deficiency, qi and blood deficiency, dizziness and tinnitus caused by stagnation of phlegm and blood stasis, insomnia and dreaminess, amnesia and somnolence, waistsoreness and limp legs, spermatorrhea and premature ejaculation, sterility infertility, hypertension, stroke sequelae, senile dementia, Parkinson's disease, paralysis agitans, multiple sclerosis andthe like, and also can be used for premature senility of middle-aged people or weakness of old people and the like.
Owner:RIZHAO HOSPITAL OF TCM

Method for determining concentrations of vancomycin and degradation product in human serum

The invention belongs to the technical field of drug concentration monitoring, and relates to a method for simultaneously determining concentrations of vancomycin and a crystalline degradation productCDP-1 in human serum by LC-MS/MS. According to the method, norvancomycin is used as an internal standard, formic acid is used for acidifying serum, quantitative acetonitrile precipitated protein is added, acetonitrile and formic acid water are used as mobile phases, and the concentrations of human serum vancomycin and CDP-1 are determined through an LC-MS/MS method. According to the method, the sampling amount is small, and pretreatment is simple and rapid. The method can be used for determining the concentrations of vancomycin and degradation products CDP-1 in serum samples of conventional clinical patients. Particularly, different degrees of CDP-1 generated after hemodialysis of patients with renal insufficiency can be quantified, so that the concentration of the antibacterial active ingredient vancomycin is reduced, an individualized vancomycin dosing scheme can be made and adjusted clinically, the clinical curative effect and the bacterial clearance rate can be improved, the generation of bacterial drug resistance is reduced, and toxic and side effects such as renal toxicity and the like are reduced.
Owner:AFFILIATED HUSN HOSPITAL OF FUDAN UNIV

Chestnut fermentation virgin pulp wine and fermentation method thereof

The invention relates to a chestnut fermentation virgin pulp wine made from chestnut as the raw material and a fermentation method thereof. The method comprises the following steps: washing, peeling and crushing chestnut, steaming for 5-6 hours, cooling to 23-27 DEG C by spreading out, saccharifying for 24 hours at the constant temperature of 25-30 DEG C after a caky starter is added, fermenting for 10-12 days at the constant temperature of 25-30 DEG C after water is added inside, and then distilling to obtain the chestnut fermentation virgin pulp wine. Based on the method disclosed by the invention, the technology and technological parameters of fermenting wine with chestnut as the raw material are optimized, and saccharomyces cerevisiae cultured with chestnut as the culture medium is used as the caky starter which is more suitable for wine fermentation technology with chestnut as the raw material. As a result, the method disclosed by the invention has the advantages of high yield, low cost and short period; the chestnut fermentation virgin pulp wine disclosed by the invention has the functions of nourishing the stomach and strengthening the spleen, promoting appetite, reinforcing the kidney, activating blood circulation and restraining bleeding, is especially suitable for aged people with liver depression and kidney insufficiency, and can achieve the efficacy of strengthening the body and curing diseases after being drunk for long time.
Owner:张建平

Traditional Chinese medicine particle for treating spleen-kidney insufficiency type IgA kidney disease as well as preparation method and application of traditional Chinese medicine particle

The invention relates to technical field of traditional Chinese medicines and particularly discloses a traditional Chinese medicine particle for treating spleen-kidney insufficiency type IgA kidney disease as well as a preparation method and application of the traditional Chinese medicine particle. Based on traditional application of radix astragali-cassia twig five-component soup, different extraction and purification process routes are compared and investigated under the guidance of a traditional Chinese medicine theory according to the monarch, minister, assistant and guide rules of traditional Chinese medicines in a prescription and an effective component group, and an optimal extraction route is optimally selected from pesticide effect screening experiments; by comprehensively utilizing testing methods of orthogonal test, single factor investigation and the like, the influences caused by a pretreatment method, extraction process parameters (extraction time, extraction number of times and solvent adding amount and the like), a purification method and relevant parameters of medicinal materials on the yield and purity of the index components in the radix astragali-cassia twig five-component soup are compared and analyzed, and optimal process parameters are obtained; and by researching a preparation process, the dose form and a preparation method are determined; and by carrying out trial production on three batches of pilot test samples, the process amplification has stability and feasibility.
Owner:SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M

Preparation method of traditional Chinese medicine for treating vomit type reflux oesophagitis

The invention provides a preparation method of a traditional Chinese medicine for treating vomit type reflux esophagitis, and belongs to the technical field of preparation methods of traditional Chinese medicines. Currently, colloidal bismuth subcitrate is adopted to treat vomit type reflux oesophagitis, and contraindicated for use by patients allergic to the medicament, patients with serious renal insufficiency and pregnant women. The preparation method is characterized by comprising the following steps of immersing the following 27 traditional Chinese medicines in water, namely bamboo shavings, tabasheer, panax pseudo-ginseng wsll. var, apricot kernel, loquat leaf, momordica grosvenori, adenophora tetraphylla, trachelioides, bamboo juice, pinellia ternate, exocarpium, concha arcae, oroxylum indicum, trichosanthes kirilowii maxim, longstamen onion bulb, tangerine seed, tangerine peel, orange, buckeye, tobacco, citron, nutgrass galingale rhizome, mangnolia officinalis, lychee seed, lychee, costustoot and liquorice; and decocting with slow fire to obtain decoction to obtain the traditional Chinese medicine for treating vomit type reflux esophagitis. The traditional Chinese medicine has the advantages of short course of treatment and high cure rate. Monarch, minister, assistant and guide medicines are compatible. Adverse reactions, allergy reactions and toxic reactions caused by Western medicaments sulfonamides and antibiotics can be avoided while the traditional Chinese medicine is administrated.
Owner:张贞美

Chronic nephritis traditional Chinese medicine for treating symptoms of edema due to kidney insufficiency and facial and general edema

The invention discloses a chronic nephritis traditional Chinese medicine for treating symptoms of edema due to kidney insufficiency and facial and general edema. The chronic nephritis traditional Chinese medicine is prepared from the following components by weight: 10 to 25g of radix et rhizoma salviae miltiorrhizae, 10 to 20g of rhizoma atractylodis macrocephalae, 20 to 30g of radix astragali seu hedysari, 10 to 25g of rhizoma imperatae, 15 to 25g of semen plantaginis, 25 to 35g of poria cocos, 15 to 25g of cortex eucommiae, 12 to 18g of cortex lycii, 15 to 30g of rhizoma alismatis, 5 to 10g of cortex cinnamomi, 10 to 15g of radix aconite lateralis praeparatae, 6 to 15g of fructus psoraleae and 8 to 15g of ootheca mantidis. According to the invention, the chronic nephritis traditional Chinese medicine is free from toxic and side effects and has good treatment effects; all medicines are cooperated, so that the effects of inducing diuresis for removing edema, tonifying spleen and regenerating body fluid, nourishing liver and kidney, and replenishing qi and blood are realized; in addition, local common medicinal materials are selected, so that the medicine is low in cost and reduces the economic burden of patients.
Owner:姚富江

Traditional Chinese medicine composition for curing liver depression and kidney insufficiency type depression disease

The invention discloses a traditional Chinese medicine composition for curing liver depression and kidney insufficiency type depression disease. The traditional Chinese medicine composition comprisesthe following raw materials in parts by weight: 3 to 8 parts of roasted radix astragali, 4 to 10 parts of mulberries, 1 to 5 parts of radix ginseng, 5 to 10 parts of semen Cuscutae, 3 to 8 parts of fructus lycii, 5 to 10 parts of fructus ligustri lucidi, 10 to 15 parts of fructus tritici levis, 5 to 10 parts of radices stellariae dichotomae, 3 to 8 parts of radix polygoni multiflori, 3 to 8 partsof rhizoma curcumae longae, 5 to 10 parts of radix curcumae, 1 to 6 parts of semen vaccariae, 3 to 8 parts of Chinese trumpet creeper, 3 to 8 parts of semen boitae, 3 to 8 parts of cortex albiziae and10 to 15 parts of fructus ziziphi jujubae. The traditional Chinese composition disclosed by the invention is high in operability, convenient to take, reasonable in matching, small in toxic and side effects and effective in treatment, has the mutual coordination effects of moistening lung, promoting the secretion of saliva or body fluid, reinforcing qi, nourishing blood, tonifying the liver and kidney, clearing deficient heat, dredging meridians and collaterals, tonifying heart and calming the nerves, and has a therapeutic action for symptoms caused by liver depression and kidney insufficiencytype depression diseases, so that the depression diseases are solved from the roots of the diseases, and the treatment cycles for the depression diseases are shortened.
Owner:尹爱兵
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products