63results about How to "Increase activity level" patented technology

Methods and systems for health and wellness management, including computer programs for implementing such methods and systems, are disclosed. An illustrative system for managing the health and wellness of plan members within a health plan can include a plan sponsor, a behavior modification program targeted to one or more plan members within the health plan, and a plan administrator adapted to monitor the progress of each plan member participating in the behavior modification program. A customizable computer exercise program can be provided as a part of the behavior modification program to promote weight loss, increase activity level, as well as other health related objectives. The computer exercise program can include a compliance module adapted to monitor the plan member's usage of the program, and a communications module for transferring data back and forth between the exercise program and administrator.

The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining α-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of α-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.

A system and method for using biometric data received from a user to generate feedback messages for transmission to the user while the user performs a physical activity. Wireless biometric sensors such as those used to monitor heart rate, blood pressure, and pulse rate are integrated into a user's diet and exercise plan and the personalized instruction that the individual receives. An expert system uses the biometric data to monitor the effectiveness of the physical activity and generate feedback messages. The expert system then sends the messages to the user's mobile device. The messages may inform the user of the biometric data, may provide positive reinforcement related to the user's progress toward a stated goal, or may suggest modifications to the physical activity to assist the user in reaching a stated goal.

The invention is an interactive wearable video game (1), in which one or more players interact with physical objects through physical actions / contact / physiological signals to control a video game. The apparatus includes a series of wireless electronic sensors (7 to 16) to be placed in the user's body / surrounding environment, detecting the user's input actions in real time—output result is visualized on a binocular see-through display glasses system (2). The invention allows for the players to move around by connecting with the physical space, and to use their full bodies to control the game, exercise and share interactions. It allows for the connection between both virtual and physical realities—mixed reality concept by augmenting the user's perceptions among the surrounding environment. Users can either communicate from maximum physical proximity through a Web connection. The invention is rechargeable by converting produced solar energy into electric energy.

A method is provided for improving the condition and / or increasing the longevity of elderly pets. The elderly pet is administered an effective amount of a nutritional composition which contains a calcium source and an antioxidant source, such as of vitamins or vitamin precursors which have antioxidant properties. Examples of such vitamins and precursors include β-carotene and vitamin E.

A method for improving activity in a pet; especially elderly cats and dogs. The pets are administered a nutritional agent which promotes the growth of bifido- and lactic-bacteria in the gastrointestinal tract of a pet. The nutritional agent may be a prebiotic or a probiotic micro-organism, or both.

The invention described herein features methods, compositions, and kits for the use of activators of PKM2 for the treatment, prevention, or amelioration of diseases related to PKM2 function, including, e.g., cancer, diabetes, atherosclerosis, restenosis, obesity, autoimmune disorders, and proliferative disorders.

The invention discloses a low-protein weanling piglet feed which comprises the following raw materials: corns, bean pulp, calcium hydrogen phosphate, dried porcine soluble, fermented bean pulp, fish meal, soybean oil, a premix, sodium chloride, phytase, a compound antioxidant, a compound acidifier, a compound enzyme preparation, a microecological preparation, limestone, L-lysine hydrochloride, L-threonine, DL-methionine, L-tryptophan and a compound traditional Chinese medicine preparation. According to the feed, the crude protein content of piglet full-price daily ration is reduced to 16% from 19%; the compound acidifier, the compound enzyme preparation, the microecological preparation and the compound traditional Chinese medicine preparation are added, so that the immunity of piglets is comprehensively improved and the use of antibiotic drugs is reduced; low-protein high-growth piglet ration is prepared, so that the misunderstanding to the feed consumption caused by farmers is eliminated, the low-protein ration formula technology is really popularized in local, the use of protein raw materials and the diarrhea of the piglets are reduced, and the cost and the N discharge are reduced.

Embodiments of the present invention generally relate to epicardial heart rhythm management. In some embodiments a method is provided for managing heart rhythm by implanting a pa device within the pericardial space of a patient. In some embodiments, an implantable device is provided for pacing the epicardial surface of a patient. The device may include a first module coupled to a second module by a tether. The first and second modules may be selectively placed for bi-ventricular pacing or for dual chamber pacing in some embodiments. Optionally the modules may be separate and may wirelessly communicate with one another and may also communicate with a heart stimulation device programmer. Optionally, a plurality of devices may be implanted in the pericardial space. A delivery device for delivering the implantable device to the pericardial space is also provided. Further embodiments provide implant retrieval devices and methods.

The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining α-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of α-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.

The invention provides an antigravity muscle exerciser comprising a garment which when worn by a user is close-fitting and covers at least the torso of said user. The garment comprises separate top and bottom portions or is a one-piece article, and has incorporated therein first portions of flexible material on each side of the torso which extend from the pelvis to beyond a respective shoulder where the portions are contiguous with a second portion of flexible material which extends across the top of the head of the user in a coronal plane. The portions of flexible material in combination have a length and elasticity which creates axial compression between the top of the head and the pelvis. The invention also provides a method of utilising the garment exercising deep posture and anti-gravity muscles.

The invention described herein features methods, compositions, and kits for the use of activators of PKM2 for the treatment, prevention, or amelioration of diseases related to PKM2 function, including, e.g., cancer, diabetes, atherosclerosis, restenosis, obesity, autoimmune disorders, and proliferative disorders.

Embodiments of the present invention generally relate to epicardial heart rhythm management. In some embodiments a method is provided for managing heart rhythm by implanting a pacing device within the pericardial space of a patient. In some embodiments, an implantable device is provided for pacing the epicardial surface of a patient. The device may include a first module coupled to a second module by a tether. The first and second modules may be selectively placed for bi-ventricular pacing or for dual chamber pacing in some embodiments. Optionally the modules may be separate and may wirelessly communicate with one another and may also communicate with a heart stimulation device programmer. Optionally, a plurality of devices may be implanted in the pericardial space. A delivery device for delivering the implantable device to the pericardial space is also provided. Further embodiments provide implant retrieval devices and methods.

The invention described herein features methods, compositions, and kits that utilize activators of pyruvate kinase M2 (PKM2) for the treatment or amelioration of disorders related to PKM2 function and characterized by abnormally low levels of serine.

This invention relates generally to a method and an apparatus for remote health monitoring of activity of daily living of patients with Type-2 Diabetes. In particular, it relates to a method of capturing vital signs data (Blood-Glucose values, weight) from medical devices, a variety of ambient sensors (on / off sensors, motion sensors, pressure-pad sensors), a body-wearable sensor (arm-band with accelerometer, stress and sleep measurements), and food / diet information uploaded via a web-based interface, then storing all the data in real-time on a secured server, and then processing it to generate short text-messages delivered via cell-phones, iPads or other ambient displays. These messages are designed to be persuasive in nature to alter human behavior. The system can also generate from the data health newsletter that is customized for the patient to educate, inform and empower the patient.

A method for sending prompt information to Social Networking Services (SNS) community users comprises the following steps: acquiring the inactive users in an SNS community; acquiring the friend relationship chains of the inactive users; acquiring the active users in the friend relationship chains; acquiring the writing operations of the active users; sending prompt information related to the writing operations of the active users to the inactive users. The method described above for sending prompt information to SNS community users can increase the success rate for activating the inactive users, and thus effectively reducing the loss of the SNS community users. Besides, a system for sending prompt information to SNS community users is also provided.

Provided are recombinant antibodies comprising one or more peptides fused to the C-terminus of the light chain constant region. Recombinant immunocytokines comprising a cytokine fused to the C-terminus of the light chain constant region are described and shown to be surprisingly active.

An alarm clock comprises at least one sensor for detecting a body activity level of a human being and is provided to produce a sequence of alarm signals. Each alarm signal within said sequence is suppressible on the detection of a predetermined body activity level. The body activity level required to suppress an alarm signal increases with each subsequent alarm signal within said sequence. A corresponding method for controlling a wake-up alarm comprises the production of a sequence of alarm signals, each alarm signal within said sequence being suppressible on the detection of a predetermined body activity level of a human being, wherein the predetermined body activity level required to suppress an alarm signal increases with each subsequent alarm signal within said sequence. The body activity level of a human being is detected during said sequence, and a present alarm signal is suppressed when the body activity level presently detected is greater than the predetermined body activity level required to suppress the present alarm signal.

The present disclosure relates to modified yeast, wherein the yeast has reduced pyruvate decarboxylase polypeptide (PDC) activity and methods of using such yeast to produce malic and / or succinic acid.

The invention relates to wound healing promoting gel and a preparation method thereof. The wound healing promoting gel is prepared by forming a gel matrix by oxidized alginate and diamine or diamidogen matters through a cross-linking reaction and compounding the following components in parts by weight: 5 to 10 parts of carbomer, 10 to 20 parts of isomalto-oligosaccharide, 0.1 to 10 parts of a wound healing promoting drug, 5 to 20 parts of a skin penetration enhancer and 40 to 70 parts of purified water. According to the wound healing promoting gel disclosed by the invention, after alginate is partially oxidized by sodium periodate which is subjected to a specific technology, carboxyl active genes in alginic acid can be activated, occurrence of the cross-linking reaction can be quickened, and the production efficiency of the gel is increased; alginate gel prepared by the invention has higher cohesive energy, is easy to form and not easy to crack, can be suitable for wounds in any parts, and is also capable of inhibiting reproduction of in-vivo harmful bacteria and generation of poisonous corrupt matters, expressing the effects of stopping bleeding, resisting bacteria, clearing wounds and promoting wound healing, and greatly shortening the healing time of the wounds.

Disclosed herein inter alia are compositions and methods useful in the treatment neurodegenerative diseases and cardiomyopathy, and for modulating the activity of PINK1.

The invention pertains to a polypeptide comprising a truncated von Willebrand Factor (VWF) and a half-life extending moiety, for use in the treatment of a blood coagulation disorder, said treatment comprising administering the polypeptide to a subject having a blood coagulation disorder and having endogenous Factor VIII (FVIII), wherein the activity level of endogenous FVIII in said subject beforetreatment with said polypeptide is reduced relative to the activity level of FVIII in normal human plasma (NHP) provided that the activity level of endogenous FVIII in said subject is at least 0.5% of the activity level of endogenous FVIII in normal human plasma (NHP), wherein the polypeptide is capable of binding to endogenous FVIII and wherein the endogenous FVIII level is increased following administration of said polypeptide.

One embodiment provides a method for creating alternative wellness activities based on tracked worker activity, the method including: utilizing at least one processor to execute computer code that performs the steps of: receiving, from one or more device sensors, a user movement pattern; identifying, based on the user movement pattern, an activity; determining, using at least one other device sensor, an alternative user movement pattern to achieve the activity, wherein said alternative increases an activity level of a user; and communicating, over a network, a message suggesting the alternative user movement pattern. Other aspects are described and claimed.

The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining α-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of α-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.

The invention provides an antigravity muscle exerciser comprising a garment which when worn by a user is close-fitting and covers at least the torso of said user. The garment comprises separate top and bottom portions or is a one-piece article, and has incorporated therein first portions of flexible material on each side of the torso which extend from the pelvis to beyond a respective shoulder where the portions are contiguous with a second portion of flexible material which extends across the top of the head of the user in a coronal plane. The portions of flexible material in combination have a length and elasticity which creates axial compression between the top of the head and the pelvis. The invention also provides a method of utilizing the garment exercising deep posture and anti-gravity muscles.

A method is provided for inhibiting or preventing adherence of cancer cells or immunocytes to their target cells or target tissues by reducing the level of activity of FX enzyme in the cells. The reduction may either be in the amount of the FX protein or in the enzymatic activity of the protein in the cells. In addition, methods and agents are provided for down-regulating or up-regulating the level of activity of FX in cancer cells and in immunocytes. The down-regulation of FX in cancer cells is provided for inhibiting or preventing metastasis of cancer cells and the up-regulation of FX activity in cancer cells is useful for increasing the immunogenicity of these cells when used in a cancer vaccine. Down-regulation of FX in immunocytes inhibits or prevents conditions such as undesired inflammatory responses, auto-immunity and transplant rejection. Up-regulation of FX activity in immunocytes is useful for enhancing an immune reaction in cases of reduced immunity of an individual. The regulation of the level of activity of FX in cancer cells and immunocytes may be achieved by contacting the cells with various agents such as antibodies, growth factors, cytokines or various combinations of such agents. The level of activity of FX in cancer cells is also used as a diagnostic and prognostic factor of metastasis and the level of activity of FX in immunocytes is used as a marker of activation useful in determining an individual's response to an immunogen.

The invention provides a multifunctional orthotic plate device for the legs, feet and ankle joints of a hemiplegic patient. The device comprises a bottom plate, a spring reset device, a pedal plate, apositioning frame, a sliding groove, an angle adjustment frame structure, a detachable message wheel structure, an auxiliary rod structure, an auxiliary holding tube structure, an antiskid cushion block and a protective strip, wherein the spring reset device is arranged in the middles of the inner sides of the bottom plate and pedal plate through bolts. The multifunctional orthotic plate device for the legs, the feet and the ankle joints of the hemiplegic patient has the advantages that an auxiliary operating rod is arranged on the upper left portion of an adjustable control rod, thereby being conductive to reducing a gap between a user and a handle when the user is located at the left side, and providing convenience for utilizing the auxiliary operating rod to control the angle of the adjustable control rod; a hook-and-loop fastener mother buckle is attached to a hook-and-loop fastener son buckle, thereby being conductive to fixing a massage lantern ring at the outer side of a rotating roller conveniently, and cooperating with a massage ball to massage the leg of the patient conveniently; and rest springs are arranged at the inner sides of an upper side mounting plate and lower side mounting plate through fixing bolts respectively, thereby being conductive to providing convenience for resetting the pedal plate.

The invention discloses a preparation method of a soil enzyme activity synergist, a product and its application. The preparation method comprises the following steps: firstly hydrolyzing soybean meal by the use of an enzyme expansion solution for soybean meal hydrolysis to obtain a hydrolysate containing active free amino acid, adding fulvic acid, and carrying out spray drying to obtain an active soil enzyme-containing carrier containing 32-35% of water; and mixing the active soil enzyme-containing carrier and soil enzyme, and packaging so as to obtain the soil enzyme activity synergist. By the soil enzyme activity synergist, cracking and degradation of soil organic matter can be raised. It can be known through practice that utilization rate of soil organic matter is raised by 0.4-0.95%. Thus, soil structure can be improved, formation of a granular structure is remarkably promoted, soil fertility and soil moisture content can be regulated, and yield and quality of crops can be enhanced. What is important is that the soil enzyme activity synergist can inhibit pollution of heavy metal in soil.