The invention relates to a pulley guide loading device, in particular to a pulley guide loading device for testing an airplane structure. The pulley guide loading device comprises anchor bolts, a first actuating cylinder mounting seat, fixing bolts, an actuating cylinder, a sensor, double connecting lugs, connecting bolts, a steel wire rope, a guide pulley seat, a pulley, pressing beams, gaskets, a turn buckle, double fixing lugs and a second actuating cylinder mounting seat. According to the pulley guide loading device, the perpendicular loading of a near-surface downward loading point of a test piece is converted into horizontal ground loading, so that the problem that the actuating cylinder cannot be perpendicularly arranged or a reserved stroke of a piston rod of the actuating cylinder is insufficient after the actuating cylinder is perpendicularly arranged, and a perpendicular test load cannot be applied due to the fact that the near-surface download loading point of the test piece is close to the ground in a test in the airplane structure is solved.