One-step addition technique for vitamin K3

Abstract

The invention relates to a novel vitamin K3 one-step processing technology; the technology is a one-step processing method; the reasonable organic solvent and catalyst are chosen to make vitamin K3. The invention reduces the refining, secondary freezing and cooling, and the secondary centrifugal processes of the product; the simple screening process replaces the complex crushing process. The concrete steps are: in the reactor, the beta menadione is put into the ethanol solution; the sodium metabisulfite and catalyst is put according to the proportion; after keeping two hours under the condition of 65 to 75 Celsius system, the solution is put into the crystallizer; the material is put at 0 Celsius system and done with the centrifugal separation; the process is to dry the wet VK3; then screen and get about 319 kilograms of dry VK3, with the content of 101.77 percent. The advantages are: first, the process is short and the operation is simple; secondly, the production rate of the single-kettle is high; thirdly, the collection rate of the product is high; fourthly, the solvent consumption is low; fifthly, the energy consumption is low; sixthly, the product quality is high.

Description

technical field [0001] The invention relates to a production process of a feed grade vitamin K3 product, in particular to a process for preparing vitamin K3 in one step in an addition process. Background technique [0002] The product trade name that the present invention relates to is vitamin K3 (VitaminK3), and chemical name is menadione sodium bisulfite (Menadione Sodium Bisulfite-MSB), and its molecular formula is C 11 h 8 o 2 ·NaHSO 3 ·3H 2 O, molecular weight 330.29. [0003] This product belongs to vitamin medicine and belongs to the most dynamic field of specialty fine chemicals. Its properties are white to light yellow crystalline powder; bitter, no odor or slight odor, easily soluble in water, hardly soluble in ethanol, almost insoluble in ether and benzene, stable at room temperature, easy to absorb moisture, easy to decompose when exposed to light , is irritating to the skin and respiratory tract. [0004] Vitamin K3 participates in the synthesis of thromb...

AI Technical Summary

Problems solved by technology

[0008] Process 1, two-step addition method: the main process (oxidation→sulfonation→refining→drying→crushing→packaging) uses one solvent for purification; low production capacity; addition and purification time: 12 to 15 hours (single batch ); comprehensive energy consumption is high

[0009] Process 2, extraction and addition method: main process: (oxidation→extraction→addition→drying→crushing→packaging) two solvents are used for purification; production capacity is low; addition and purification time: 9 to 12 hours (single batch ); comprehensive energy consumption is high