Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation for biological packing drainage used for rectocele repairing and its using method

A technology of drainage and rectum, which is applied in medical science, prosthesis, surgery, etc., can solve the problems of unavoidable tension and high recurrence rate in repaired parts, and achieve the effect of reducing hospitalization time, low recurrence rate and promoting healing

Inactive Publication Date: 2008-02-20
杨晓东 +4
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The above-mentioned three kinds of operation methods all directly suture and repair the weak area of ​​the anterior wall of the lower end of the rectum, the rectovaginal septum, and the posterior wall of the vagina. Due to the unavoidable tension in the repaired area, the postoperative recurrence rate is high, as high as 30%.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1: Application of fresh porcine dermal tissue to prepare biological tampon drainage for rectocele repair surgery

[0029] Collect fresh porcine dermal tissue and cut into 1-3cm 3 Small pieces were immediately fixed with 2% formaldehyde solution for 2 to 4 hours, and washed several times with distilled water. Then, the tissue was incubated with 1N sodium hydroxide solution at a constant temperature of 20°C for 24 hours for decellularization. Then, the tissue was washed with sodium phosphate buffer until the tissue became translucent. Then the washed tissue was incubated in glycine-HCl buffer to eliminate residual fixative and lower the pH value until the pH value was 7.35-7.55.

[0030] Soak the treated tissue in a homogeneous aqueous solution of mixed 50 mg / ml gentamicin sulfate and 50 mg / ml metronidazole, take it out after 10 minutes, dry it, and then soak the tissue in 50 mg / ml dodecane After being dried in sodium sulfate solution, crushed, and pressed into...

Embodiment 2

[0031] Example 2: Surgical method for placing hemorrhoidal biotampon drainage

[0032] 1. Take an arc-shaped incision of about 3 cm on the side of the perineum near the vagina, cut open the skin and subcutaneous tissue, and bluntly separate the anal sphincter leading edge to separate the loose tissue of the rectovaginal septum, and the separation range reaches 1 cm above the weak area , to reach the anterior cross of the separated perineal body and levator ani.

[0033] 2. Pre-cut the biotampon drainage prepared in Example 1 into a suitable size with scissors according to the size of the weak area.

[0034] 3. Stuff the cut biological packing drainage in the weak area of ​​the rectovaginal diaphragm, pay attention to spread neatly and fix it.

[0035] 4. Lead the outer end of the biotampon drainage through the perineal incision.

[0036] 5. Suture the subcutaneous tissue and skin.

[0037] 6. Remove the excess part of the outer end of the biotampon drainage so that the oute...

Embodiment 3

[0039] Embodiment 3: curative effect

[0040] Case selection: A total of 15 cases of rectocele were selected from June 2003 to October 2007, all of whom were middle-aged and elderly women. The biotampon drainage prepared in Example 1 was used, and the method provided in Example 2 was used for treatment. After follow-up, the results are as follows:

[0041]Rectal defecography reexamination in 15 patients showed that the rectocele disappeared without stool retention. No recurrence was found in the follow-up of 6 months to 4 years, and the cure rate was 100%. The postoperative hospital stay was 3 to 6 days, with an average of 4.8 days. Postoperatively, 2 cases complained of pain, all of which could be tolerated without treatment. The patient's anal shape returned to normal, without prolapse of hemorrhoids, smooth defecation, no blood in the stool, anal stenosis, infection, and fecal incontinence.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Login to View More

Abstract

The present invention relates to a preparation method of drain of biological plugging applied in the operation of repair rectocele and the application. The drain of biological plugging is made with human or animal skin tissue as the material, preparing in the procedures of fixing, cell extraction and coating with antibiotic layer; the drain is placed in the weak area of rectovaginal septa via operation, realizing the unstressing defect repair, eliminating the weak area and rebuilding the anterior wall of rectum. The present invention provides a biological scaffold for concrescence of repaired wound surface, remarkably advances the concrescence of wound surface and greatly shortens the concrescence time of wound surface as well as reduces the hospitalizing time; in addition, the drain of biological plugging of the present invention is coated with an antibiotic layer and has the drain effect, therefore, the infection of the wound surface is remarkably decreased; the efficiency of the drain of biological plugging of the present invention is 100 percent with a low recurrence rate. And the incident ratio of pains, fecal incontinence, stenosis of anal canal and other complicating diseases are reduced after the operation.

Description

Technical field: [0001] The invention relates to a preparation method and application of a biological tampon drainage used in rectocele repair surgery. The biological tampon drainage is prepared from human or animal skin tissue through fixation, decellularization, and introduction of antibiotic coating. The defect is repaired tensionally, eliminating areas of weakness and reconstructing the anterior wall of the rectum. It provides a biological scaffold for the healing of the repaired wound, which can significantly promote the healing of the wound, significantly reduce the healing time of the wound, and reduce the length of hospitalization; in addition, the biological tampon drainage has an antibiotic coating, and can play the role of drainage, thus significantly Reduce wound infection; the effective rate of applying the biological tampon drainage provided by the invention is as high as 100%, and the recurrence rate is low. Moreover, it significantly reduces the incidence of ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L27/36A61L31/14
Inventor 杨晓东杨新庆王振军陈朝文赵博
Owner 杨晓东
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com